나성원 교수
Sung-Won Na
연세대학교 의료법윤리학과 · 의학
연구실 소개
나성원 교수의 연구실은 중환자 치료 및 집중치료 분야에서 핵심적인 임상 문제를 해결하고자 하는 연구를 지속적으로 수행하고 있습니다. 특히 패혈성 쇼크 환자에서 팀 기반 치료 모델이 치료 성과에 미치는 영향, 내시경적 심장초음파 검사 시 부상 위험 최소화 전략, 폐동맥고혈압에서 교감신경 차단이 항산화 기전을 통해 유용한 치료법이 될 수 있는지에 대한 기전 연구를 중심으로 진행되고 있습니다. 또한 집중치료실의 소음 환경 분석과 기도 삽입 시 치아 손상 위험 요인 분석을 통해 임상 현장에서의 안전성 향상에도 기여하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15OBJECTIVE: To examine the impact of implementing sepsis bundle in multiple Asian countries, having 'team' vs. 'non-team' models of patient care. DESIGN: Prospective cohort study. SETTING: Eight urban hospitals, five countries in Asia. PARTICIPANTS: Adult patients with severe sepsis or septic shock. INTERVENTIONS: Implementation was divided into six quartiles: Baseline, Education and four Quality Improvement quartiles. MAIN OUTCOME MEASURES: Quarterly bundle compliance and in-hospital mortality w
BACKGROUND: Intraoperative transesophageal echocardiography has become a routine part of monitoring in patients with cardiac disease. However, insertion of a transesophageal echocardiography probe can be associated with oropharyngeal, esophageal, and gastric injuries. The purpose of this study was to determine whether insertion of a transesophageal echocardiography probe under direct laryngoscopic visualization can reduce the incidence of oropharyngeal mucosal injury. METHODS: Eighty patients un
It has been recognized that the sympathetic nervous system is activated in pulmonary arterial hypertension (PAH), and abnormal sympathetic hyperactivity leads to worsening of PAH via endothelial dysfunction. The purpose of this study was to examine whether sympathetic ganglion block (SGB) can treat PAH by increasing the availability of nitric oxide (NO). PAH was induced in rats by 50 mg/kg of subcutaneous monocrotaline. After 2 weeks, daily injections of ropivacaine into the left superior cervic
The study was registered at ClinicalTrials.Gov (number NCT03156205).
Noise generated in the intensive care unit (ICU) adversely affects both critically ill patients and medical staff. Recently, several attempts have been made to reduce ICU noise levels, but reliable and effective solutions remain elusive. This study aimed to provide evidence on noise distributions in the ICU to protect patient health. For one week, we measured noise levels in isolated rooms, open units, and nursing stations in medical, surgical, and pediatric ICUs, respectively. We additionally a
In this retrospective case-control study, we evaluated peri-operative dental injury risk factors following tracheal intubation. Ninety-four of 290,415 patients experienced dental injury following tracheal intubation over a 10-y period. A control group was matched for surgery type and intubating anaesthetist. The incidence of dental injury was 0.03%. Univariate analysis revealed that previous and current difficult intubation, male gender, hepatitis, neurological disease, anticonvulsant use, pre-e
BACKGROUND: Contrast medium used for radiologic tests can decrease renal function. However there have been few studies on contrast-associated acute kidney injury in intensive care unit (ICU) patients. The objective of this study was to evaluate the incidence, characteristics, and outcome of contrast-associated acute kidney injury (CA-AKI) patients using the Risk, Injury, Failure, Loss, and End-stage kidney disease (RIFLE) criteria in critically ill patients in the ICU. METHODS: We conducted a re
BACKGROUND: Although active infective endocarditis (IE) is known as a risk factor for decreased heparin responsiveness during cardiopulmonary bypass (CPB), evidence is lacking in patients with stabilized IE. We investigated whether heparin responsiveness was still altered in stabilized IE patients undergoing cardiac surgery in a prospective, controlled trial. METHODS: A total of 16 patients with stabilized IE without signs of active inflammation (IE group) and 48 patients without systemic infect
BACKGROUND: Pneumoperitoneum-induced oxidative stress and organ injury are known to be associated with nitric oxide (NO) inactivation. Because arginase competes with NO synthase (NOS) for a common substrate, L-arginine, arginase inhibition may increase NO bioavailability. Therefore, we evaluated the ability of the arginase inhibitor, 2 (S)-amino-6-boronohexanoic acid (ABH), to attenuate pneumoperitoneum-induced decrease of NO bioavailability and lung injury. METHODS: Thirty rats were randomly di
OBJECTIVE: Milrinone has been known to dilate the internal thoracic artery (ITA) and the radial artery (RA). The effect of milrinone, however, on each graft is unclear when the left ITA (LITA) and the RA form a Y-graft. This study evaluated the changes in blood flow of a composite Y-graft in response to milrinone. METHODS: Thirty-two patients undergoing an isolated coronary artery bypass graft surgery were included in this study. A Y-graft was created with an in situ LITA and free RA graft attac
Na, Sungwon; Kim, Chang Siok; Kim, Ji Young; Cho, Hin Seon; Kim, Ki Jun Author Information
최근 무선 센서 네트워크(WSN)이 침입 탐지와 생태, 환경, 대기, 산업, 교통, 화재 감시 등에 다양하게 적용되어 사용되고 있다. 본 논문에서는 에너지 효율적인 클러스터링 알고리즘을 제안한다. 제안 알고리즘은 수신전력을 바탕으로 하여 최적위치의 클러스터헤드를 선출하고 이를 통해 균일한 클러스터사이즈를 가지도록 한다. 또한 최대 깊이가 제한된 MST를 이용한 라우팅 트리를 구성하고 멀티 홉 전송을 통해 센서 노드의 위치에 관계없이 균일한 에너지 소모를 유도하도록 하였다. 이를 통해 제안 알고리즘은 기존의 LEACH나 HEED에 비해 노드의 에너지 소모를 감소시키고 균등한 에너지 소모를 유도하여 네트워크 수명을 증대시킬 수 있다. 시뮬레이션 결과 제안 알고리즘이 공평한 에너지 소모를 통해 네트워크 수명을 증대시킬 수 있음을 확인하였다. Recently, wireless sensor networks(WSNs) are widely used for intrusion detection an
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