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이선욱 교수

Sung Wook Lee

고려대학교 신경과 · 신경과학

연구실 소개

이선욱 교수의 연구실은 내과성 어지럼이와 메니에르병을 비롯한 내이성 전정질환의 기전 규명과 정밀 진단을 목표로 합니다. 특히 전정반사 기능 평가, 혈관성 뇌경색의 전정신경핵 영역 영향 분석, 내이신경종 등의 희귀 전정질환의 임상적 특성과 영상유전자적 특징을 다각도로 연구하고 있습니다. 고해상도 전정기능검사 및 뇌경색 환자에서의 혈관교착 상태 분석을 통해 예후 예측 모델을 구축하고 있습니다.

메니에르병전정반사기능내이신경종뇌간경색어지럼증

연구 현황

논문 수
134
총 인용 수
1,264
최근 5년 논문
67
주요 분야
신경과학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
67총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
259총합
20222023202420252026

주요 논문

15
1
논문|인용수 76·2016
Comparison of caloric and head‐impulse tests during the attacks of Meniere's disease
Sun‐Uk Lee, Hyo‐Jung Kim, Ja‐Won Koo, Ji‐Soo Kim
SJR Q1The Laryngoscope

OBJECTIVES/HYPOTHESIS: To aid in diagnosis of Meniere's disease (MD) during the attacks using caloric and head-impulse tests (HITs). STUDY DESIGN: Retrospective case series review. METHODS: We analyzed the results of bithermal caloric and HITs during the attacks in 16 patients with MD. Quantitative analyses of HITs were conducted using a magnetic search coil technique. RESULTS: In unilateral MD (14 patients, 42 semicircular canals), the head impulse gain of the vestibulo-ocular reflex (VOR) was

NeurologyNeuroscience
2
논문|인용수 76·2015
Dorsal Medullary Infarction
Sun‐Uk Lee, Seong-Ho Park, Jeong-Jin Park, Hyo Jung Kim, Moon‐Ku Han, Hee‐Joon Bae, Ji‐Soo Kim
SJR Q1Stroke

BACKGROUND AND PURPOSE: The characteristics of infarctions restricted to the dorsal medulla have received little attention. This study aimed to define the distinct clinical features of dorsal medullary infarction. METHODS: Of the 172 patients with a diagnosis of medullary infarction at Seoul National University Bundang Hospital from 2003 to 2014, 18 patients with isolated dorsal medullary infarction were subjected to analyses of clinical and laboratory findings. RESULTS: All patients presented a

NeurologyNeuroscience
3
논문|인용수 48·2016
Impaired Tilt Suppression of Post-Rotatory Nystagmus and Cross-Coupled Head-Shaking Nystagmus in Cerebellar Lesions: Image Mapping Study
Sun‐Uk Lee, Jeong‐Yoon Choi, Hyo‐Jung Kim, Jeong-Jin Park, David S. Zee, Ji‐Soo Kim
SJR Q1The Cerebellum
NeurologyNeuroscience
4
논문|인용수 42·2016
Differentiating Carotid Terminus Occlusions into Two Distinct Populations Based on Willisian Collateral Status
Sun‐Uk Lee, Ji Man Hong, Sun Yong Kim, Oh Young Bang, Andrew M. Demchuk, Jin Soo Lee
SJR Q1Journal of StrokeOA

Favorable outcomes in STO group suggested that the outcomes of acute ICA terminus occlusions depend on Willisian collateral status. Documenting the subtypes on computed tomographic angiography would help predict patient outcome.

EpidemiologyMedicine
5
논문|인용수 40·2015
Head-shaking and Vibration-induced Nystagmus During and Between the Attacks of Unilateral Ménière’s Disease
Sun‐Uk Lee, Hyun-Ju Kee, Seung Soo Sheen, Byung Yoon Choi, Ja‐Won Koo, Ji‐Soo Kim
SJR Q1Otology & Neurotology

The characteristic patterns of HSN and VIN during each phase of MD would aid in defining the acute phases of MD and understanding the underlying vestibular pathophysiology.

NeurologyNeuroscience
6
논문|인용수 34·2018
Recurrent spontaneous vertigo with interictal headshaking nystagmus
Sun‐Uk Lee, Jeong‐Yoon Choi, Hyo‐Jung Kim, Ji‐Soo Kim
SJR Q1Neurology

The clinical features and characteristics of HSN in our patients indicate a hyperactive and asymmetric velocity-storage mechanism that gives rise to intermittent attacks of spontaneous vertigo probably when marginal compensation of underlying pathology is disrupted by endogenous or exogenous factors.

NeurologyNeuroscience
7
논문|인용수 34·2019
Intralabyrinthine Schwannoma: Distinct Features for Differential Diagnosis
Sun‐Uk Lee, Yun Jung Bae, Hyo‐Jung Kim, Jeong‐Yoon Choi, Jae‐Jin Song, Byung Yoon Choi, Byung-Se Choi, Ja‐Won Koo, Ji‐Soo Kim
SJR Q2Frontiers in NeurologyOA

<b>Objectives:</b> The aim of this study was to delineate the clinical and laboratory features suggestive of intralabyrinthine schwannoma (ILS). <b>Methods:</b> We compared the clinical features of 16 patients with ILS, who had been diagnosed at the Seoul National University Bundang Hospital from 2003 to 2018, with those of 18 patients with symptomatic unilateral intracanalicular schwannoma and randomly selected 20 patients with definite or probable unilateral Meniere's disease (MD). <b>Results:

NeurologyNeuroscience
8
논문|인용수 33·2024
Expanding Clinical Spectrum of Anti-GQ1b Antibody Syndrome
Sun‐Uk Lee, Hyo‐Jung Kim, Jeong‐Yoon Choi, Kwang‐Dong Choi, Ji‐Soo Kim
SJR Q1JAMA Neurology

Importance: The discovery of the anti-GQ1b antibody has expanded the nosology of classic Miller Fisher syndrome to include Bickerstaff brainstem encephalitis, Guillain-Barré syndrome with ophthalmoplegia, and acute ophthalmoplegia without ataxia, which have been brought under the umbrella term anti-GQ1b antibody syndrome. It seems timely to define the phenotypes of anti-GQ1b antibody syndrome for the proper diagnosis of this syndrome with diverse clinical presentations. This review summarizes th

NeurologyMedicine
9
논문|인용수 32·2014
Pseudo-Spontaneous and Head-Shaking Nystagmus in Horizontal Canal Benign Paroxysmal Positional Vertigo
Sun‐Uk Lee, Hyo‐Jung Kim, Ji‐Soo Kim
SJR Q1Otology & Neurotology

HSN is more common and mostly contralesional in apogeotropic HC-BPPV. HSN may be a lateralizing sign in apogeotropic HC-BPPV. Different prevalence and patterns of HSN in apogeotropic and geotropic HC-BPPV suggest dissimilar cupular dynamics in those disorders.

NeurologyNeuroscience
10
논문|인용수 31·2014
Epileptic nystagmus: A case report and systematic review
Sun‐Uk Lee, Hong-Il Suh, Jun Young Choi, Kyun Huh, Hyo‐Jung Kim, Ji‐Soo Kim
Epilepsy & Behavior Case ReportsOA

Even though the localizing value of epileptic nystagmus seems limited in previous reports, the fast phase of epileptic nystagmus was almost always directed away from the epileptic focus that mostly arose from the posterior part of the cerebral hemisphere.

Psychiatry and Mental healthMedicine
11
리뷰|인용수 29·2019
Acute vestibular syndrome associated with anti-GQ1b antibody
Sun‐Uk Lee, Hyo‐Jung Kim, Jeong‐Yoon Choi, Jong Kuk Kim, Ji‐Soo Kim
SJR Q1Neurology

Anti-GQ1b antibody may cause acute vestibulopathy by involving either the central or peripheral vestibular structures. AVS may constitute a subtype of anti-GQ1b antibody syndrome.

NeurologyMedicine
12
논문|인용수 26·2016
Normal Caloric Responses during Acute Phase of Vestibular Neuritis
Sun‐Uk Lee, Seong-Ho Park, Hyo‐Jung Kim, Ja‐Won Koo, Ji‐Soo Kim
SJR Q2Journal of Clinical NeurologyOA

Normal findings in caloric tests should be interpreted with caution during the acute phase of suspected VN. Follow-up evaluation should be considered when the findings of the initial caloric test are normal, but VN remains the most plausible diagnosis.

NeurologyNeuroscience
13
논문|인용수 24·2020
Evolution of the vestibular function during head impulses in spinocerebellar ataxia type 6
Sun‐Uk Lee, Ji‐Soo Kim, Hyo‐Jung Kim, Jeong‐Yoon Choi, Ji‐Yun Park, Jong‐Min Kim, Xu Yang, Jong‐Min Kim, Xu Yang
SJR Q1Journal of Neurology
NeurologyNeuroscience
14
리뷰|인용수 24·2020
Bilateral Vestibular Dysfunction
Sun‐Uk Lee, Hyo‐Jung Kim, Ji‐Soo Kim
SJR Q2Seminars in Neurology

Bilateral vestibular dysfunction (BVD) refers to hypofunction of the vestibular nerves or labyrinths on both sides. Patients with BVD present with dizziness, oscillopsia, and unsteadiness, mostly during locomotion, which worsen in darkness or on uneven ground. Although aminoglycoside ototoxicity, Meniere's disease, infection, and genetic disorders frequently cause BVD, the etiology remains undetermined in up to 50% of the patients. The diagnosis of BVD requires both symptoms and documentation of

NeurologyNeuroscience
15
논문|인용수 21·2020
Evolution in the Findings of Head-Impulse Tests During the Attacks of Menière's Disease
Sun‐Uk Lee, Hyo‐Jung Kim, Jeong‐Yoon Choi, Ja‐Won Koo, Xu Yang, Ji‐Soo Kim
SJR Q1Otology & Neurotology

OBJECTIVE: To determine the vestibulo-ocular reflex (VOR) performance during the attacks of Menière's disease (MD) using video head-impulse tests (video-HITs) according to each ictal phase. STUDY DESIGN: Retrospective case series review. METHODS: We analyzed the results of video-HITs in 24 patients with unilateral definite MD during and between the attacks. RESULTS: The head impulse gain of the VOR was usually normal (81%, 39 of the 48 semicircular canals [SCCs] in 16 patients) in the affected e

NeurologyNeuroscience

대표 연구 분야

NeurologyPathology and Forensic MedicineSurgeryOphthalmologyCellular and Molecular NeuroscienceEpidemiology

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