신승호 교수
Sungho Shin
연세대학교 · 의학
연구실 소개
신승호 교수의 연구실은 주로 청력 및 청각 기능의 평가와 보존, 특히 청소추종성 난청과 중이질환의 진단 및 치료 전략 개발에 초점을 맞추고 있습니다. 기존의 보조 청력 측정 기기와의 정확도 비교 및 신뢰도 검증을 통해 보다 정밀한 보행 및 청력 평가 기술의 표준화를 추구하고 있으며, 특히 Wnt/β-catenin 경로를 조절하는 소분자 약물이 탈모 치료에 활용될 수 있는 가능성을 탐색하고 있습니다. 이와 더불어 만성 중이염 환자의 수술 결과 평가 및 장기적 추적 관찰을 통해 최적의 치료 전략 수립에 기여하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15[Purpose] The purpose of this study was to investigate the concurrent validity and test-retest reliability of the recently introduced OPTOGait Photoelectric Cell System for the assessment of spatio-temporal parameters of gait. [Subjects] Twenty healthy young adults (mean age = 27.35, SD = 7.4) were asked to walk 3 times on walkway at a comfortable speed. [Methods] Concurrent validity was assessed by comparing data obtained using the OPTOGait and GAITRite systems, and reliability was assessed by
Our findings indicate that small molecules that activate the Wnt/β-catenin pathway, such as VPA, can potentially be developed as drugs to stimulate hair re-growth.
This proposed staging is simple and easily applicable for use when deciding the treatment plan for patients with EACC.
There is considerable debate in the management of almost every complication of cholesteatoma. Multicentric studies to compare the efficacies of various treatment modalities are the need of the hour to come to definitive conclusions regarding the best treatment options.
The data from KNHANES 2010-2012 showed gender differences at hearing thresholds of 3 kHz, 4 kHz, and 6 kHz in a highly-screened population. The most significant gender difference in relation to hearing threshold was observed at 4 kHz. The hearing thresholds at all of the tested frequencies worsened with increasing age. The mean hearing thresholds suggested in this study will be useful for the formulation of healthcare-related hearing policies and used as reference data for disability ratings for
A retraction pocket was observed in three cases (6.7%). Slight protrusion of partial ossicular replacement prosthesis (PORP) and lateral healing of drum was observed in one case each, and there were two cases of postoperative infection. The number of cases with an air-bone gap (ABG)<20 dB increased from 9 (23%) cases before operation, to 20 cases (51%) after operation. The ABG average statistically decreased from 30.0 dB to 24.0 dB, and the mean air conduction thresholds decreased from a preoper
In this study, full electrode insertion was achieved in all cases where the same type of electrode was used during initial and revision CI. In contrast, we noticed incomplete insertion in 4 of 5 patients who had revision electrodes that differed from initial electrodes. While incomplete electrode insertion does not necessitate poor speech performance, some patients with incomplete electrode insertion certainly experience it. Therefore, electrode selection requires circumspection in revision CI.
Cochlea macrophages regulate cochlea inflammation and may harbors the potentials to protect hearing function from injury, including acoustic overstimulation. Cochlea macrophage numbers increase at 3–7 days after acoustic stimulation. However, the exact timing of macrophage infiltration and maturation from inflammatory monocytes is unclear. Furthermore, neutrophils may also be involved in this process. Therefore, in this study, we investigated time-dependent immune cell infiltration, macrophage t
OBJECTIVES: Noise exposure leads to an increase in the macrophage population. This increment is thought to be caused by the transformation of infiltrated monocytes into macrophages rather than by proliferation of the cochlear resident macrophages. However, studies on infiltrated monocytes in the cochlea are scarce. Thus, we aimed to investigate the infiltration of monocytes and their transformation into macrophages after noise exposure. METHODS: In wild-type and CX3CR1+/GFP C57/B6 mice, inflamma
To study the effects of gait training with additional weight and gait training with non-additional weight on balance ability and gait ability in patients with chronic stroke through comparative analysis.
Neuroendocrine tumors originating in the middle ear are rare, and presentation with facial paralysis is extremely uncommon. A 19-year-old woman with a history of transient facial paralysis presented with a right-sided middle ear mass. Surgical exploration of the tympanic cavity was performed using a transcanal endoscopic approach. Histopathologic examination confirmed the diagnosis of a middle ear neuroendocrine tumor. After surgical excision of the tumor, no recurrence or facial paralysis occur
Merkel cell carcinoma is an extremely rare neuroendocrine neoplasm of the external auditory canal (EAC) skin, which requires wide excision and adjuvant radiation due to a high recurrence rate. In this report, we describe a case of Merkel cell carcinoma arising from the EAC which was successfully treated with endoscopic excision. A 32-years-old female patient with a history of papillary thyroid cancer was diagnosed with an EAC tumor incidentally. There was a erythematous papular lesion on the pos
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