김수지 교수

In this study, we used a continuity theory of aging to examine bridge employment. Excellent health, organizational tenure, and having working spouses and dependent children were positively associat...

OBJECTIVES: To analyze the treatment outcomes and the effects of adjuvant radiotherapy (RT) in patients with synovial sarcoma (SS). MATERIALS AND METHODS: The medical records of 103 patients treated with definitive surgery for SS, with/without RT, from August 1982 to July 2013 were reviewed retrospectively. The median age of the patients was 33 years (range, 5 to 72 y). The most frequent tumor location was the extremities (79 patients, 77%). Seventy-five patients (73%) received adjuvant RT and 2

BACKGROUND: The purpose of this retrospective study is to compare the treatment results of locally advanced hypopharyngeal carcinoma according to treatment modalities. METHODS: Seventy-three patients with locally advanced hypopharyngeal carcinoma treated at the Department of Therapeutic Radiology, Seoul National University Hospital, between August 1979 and July 1997 were retrospectively analyzed. Twenty-three patients were treated with radiotherapy (RT) alone, 18 patients were treated with surge

Preeclampsia (PE) is a pregnancy-specific disorder associated with hypertension and proteinuria. Since there is no proven method to treat PE, early prediction and accurate diagnosis are essential for appropriate management of the disease. Thus, reliable biomarkers for diagnosing PE need to be identified and evaluated. We analyzed serum-soluble factors and miRNAs in 92 patients with PE and an equal number of healthy controls to identify new useful biomarkers for PE. Serum miR-31-5p, miR-155-5p, a

The radioprotective effects of granulocyte colony-stimulating factor (GCSF) were further investigated with respect to the testicular system. Recombinant human GCSF (100 μg kg(-1) body weight/day) was administrated to male C3H/HeN mice by subcutaneous injection for three consecutive days before pelvic irradiation (5 Gy) and histopathological parameters were assessed at 12 h and 21 days post-irradiation (pi). The GCSF protected the germ cells from radiation induced- apoptosis (P < 0.01 vs. irradia

During the founding of North Korea, competing visions of an ideal modern state proliferated. Independence and democracy were touted by all, but plans for the future of North Korea differed in their ideas about how everyday life should be organized. Daily life came under scrutiny as the primary arena for social change in public and private life. In Everyday Life in the North Korean Revolution, 1945–1950 , Kim examines the revolutionary events that shaped people's lives in the development of the D

Hyperthermia therapy is a treatment modality in which tumor temperatures are elevated to higher temperatures to cause damage to cancerous tissues. Numerical simulations are integral in the development of hyperthermia treatment systems and in clinical treatment planning. In this study, simulations in radiofrequency hyperthermia therapy are reviewed in terms of their technical development and clinical aspects for effective clinical use. This review offers an overview of mathematical models and the

본 연구의 목적은 도시와 농어촌 노인의 고독감과 죽음불안, 사회적 자본에 대한 인식을 비교하고 고독감과 죽음불안 간 관계에서 사회적 자본의 조절 효과가 있는지 검증하는 데에 있다. 이를 위해 SSK 고령사회와 사회자본 연구센터에서 전국 만 65세 이상의 노인을 대상으로 2018년도에 실시된 「노인의 건강한 노화 및 웰다잉에 관한 연구」 설문 데이터를 바탕으로 서울특별시 및 6개의 광역시에 거주하는 총 839명의 도시 노인과 군단위 지역에 거주하는 322명의 농어촌 노인을 연구 대상자로 사용하였다. 주요 통계분석방법으로는 인구학적 특성과 주요 변수에 대한 도시와 농어촌 노인의 비교를 위해 기술 통계 및 t-test와 χ2 test를 실시하였고, 고독감과 죽음불안과의 관계와 사회자본의 조절효과를 검증하기 위하여 집단 별 이항 로지스틱 회귀분석을 실시하였다. 연구 결과, 주요 연구 변인에서 도시와 농어촌 노인들의 유의미한 차이가 발견되었다. 도시 노인은 농어촌 노인에 비해 죽음불안을 보고

Higher TLG (&gt;19.0) on FDG PET/CT during RT was a poor prognostic factor for overall survival (OS) (p = 0.001) and progression-free survival (PFS) (p = 0.007). In the multivariate analysis, TLG during RT as a continuous variable was significantly associated with OS and PFS rate (p = 0.023 and p = 0.016, respectively). Tumor response worse than partial remission at 1 month after RT was another independent prognostic factor for PFS (p = 0.024). Conclusions: Higher TLG of the primary tumor on FDG

Recent advances in sarcoma genomics have identified novel mutations in the PI3K pathway in human sarcomas. Here, we use a mouse model of primary soft-tissue sarcoma for preclinical testing of doxorubicin and inhibitors of the PI3K pathway: BKM120 (PI3K inhibitor) and BEZ235 (a dual PI3K/mTOR inhibitor). Doxorubicin-treated tumors (n = 15) showed a partial response rate of 6.6%, just as the majority of human sarcomas do not respond to doxorubicin. Treatment with BKM120 elicited a partial response

Women today are struggling with all their passion and all their strength day and night for the creation of a new history of a democratic country. Today in the streets, men, women, the old, the young, everyone stops to listen to the women. ———Nam Hyǒn-sǒ, “Women of a New Country,” January 1947 In Korea from ancient times, the master of the home was thought to refer to the husband … we now realize that the master of the home must be the woman, that is, the wife or mother. ———Chang Chǒng-suk, “The

While North Korea accused South Korea of starting a “civil war” ( naeran ) during the Korean War, it has now moved away from such depictions to paint the war as an American war of imperialist aggression against Korea that was victoriously thwarted under the leadership of Kim Il Sung. In this regard, it may be more than a coincidence that the Victorious Fatherland Liberation War Museum in Pyongyang was built in the early 1970s, just as the Vietnam War drew to a close with a Vietnamese victory. Th