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함태수 교수

Tae Soo Ham

성균관대학교 의학과

연구실 소개

함태수 교수의 연구실은 주로 통증 관리와 관련된 신경생물학적 메커니즘을 규명하고, 이를 바탕으로 비약리적 통증 완화 전략을 개발하는 데 초점을 맞추고 있습니다. 특히 전기자극 침술, 페퍼민트 냄새, 신경병성 통증 모델에서의 약물 치료 등 다양한 통증 완화 방법의 효과와 기전을 실험적으로 분석하고 있으며, 특히 마취 및 통증 완화에 영향을 주는 뇌파 지표(BIS, AAI)와의 연관성에 대해서도 연구를 진행하고 있습니다. 이는 환자의 조기 회복과 안정적인 마취 유지를 위한 임상적 응용을 목표로 하고 있습니다.

통증 관리신경병성 통증전기자극 침술마취 깊이 모니터링비약리적 통증 완화

연구 현황

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32
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최근 5년 논문
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연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
10총합
2009
2010
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2015
5개년 연도별 피인용 수
27총합
20092010201120132015

주요 논문

15
1
논문|인용수 22·2007
The Effect of 2 Hz and 100 Hz Electrical Stimulation of Acupoint on Ankle Sprain in Rats
함태수
http://kmbase.medric.or.kr/Main.aspx?d=KMBASE&m=VIEW&i=0191120070220020347

The electrical stimulation of acupoint (ESA) releases several endogenous neuropeptides, which play important roles in management of pain and inflammation. ESA with low and high frequencies has been shown to release different neuropepides, suggesting its various therapeutic effects. Pain and edema are major problems for ankle sprain. However, there have been few reports on the effects of ESA for ankle sprain. We aimed to investigate that ESA can reduce pain and edema resulting from ankle sprain,

2
논문|인용수 21·2006
A Correlation between Low Back Pain and Associated Factors: A Study Involving 772 Patients who Had Undergone General Physical Examination
Min A Kwon, 심우석, 김명희, 곽미숙, 함태수, 김갑수, 김정수, 최윤호, Jeong Heon Park, 조현성, Tae Hyeong Kim
http://kmbase.medric.or.kr/Main.aspx?d=KMBASE&m=VIEW&i=0191120060210061086

Many factors are associated with the development of low back pain. Among them, exercise, obesity, smoking, age, educational level and stress are the most common. This study examined the association of these factors with low back pain. An additional aim was to determine a procedure for preventing low back pain. This study analyzed the responses to a questionnaire sent to 772 individuals who had undergone a medical examination at this hospital in 2003 and excluded the individuals who had shown sym

3
논문|인용수 11·2007
Risk Factors for an Intraoperative Arrhythmia during Esophagectomy
함태수, 이정진, 양미경, 김지애
http://kmbase.medric.or.kr/Main.aspx?d=KMBASE&m=VIEW&i=0311120070480030474

Purpose: Arrhythmias after an esophagectomy (most commonly atrial fibrillation) are a significant contributing factor to patient morbidity. However, the significance of an intraoperative arrhythmia is not completely understood. The aim of this retrospective study was to determine the occurrence and risk factors for developing intraoperative arrhythmias in patients undergoing an esophagectomy. Materials and Methods: We reviewed the records of 427 patients who underwent a transthoracic esophagecto

4
논문|인용수 11·2011
Effect of Combined Single-Injection Femoral Nerve Block and Patient-Controlled Epidural Analgesia in Patients Undergoing Total Knee Replacement
Ae-Ryung Lee, Sangwook Ko, 최덕환, 최수주, 함태수, 김가현, 문영완
http://kmbase.medric.or.kr/Main.aspx?d=KMBASE&m=VIEW&i=0311120110520010145

Purpose: Total knee replacement is one of the most painful orthopedic procedures, and effective pain relief is essential for early mobility and discharge from hospital. The aim of this study was to evaluate whether addition of single-injection femoral nerve block to epidural analgesia would provide better postoperative pain control, compared to epidural analgesia alone, after total knee replacement. Materials and Methods: Thirty-eight patients received a single-injection femoral nerve block with

5
논문|인용수 10·2009
Protective Effects of Gabapentin on Allodynia and α2δ1-Subunit of Voltage-dependent Calcium Channel in Spinal Nerve-Ligated Rats
함태수, 안현주, 배창대, 임승운, 조현성, 이상민, 심우석, 김지애, 곽미숙, 최수주, 김한섭
Journal of Korean Medical Science

This study was designed to determine whether early gabapentin treatment has a protective analgesic effect on neuropathic pain and compared its effect to the late treatment in a rat neuropathic model, and as the potential mechanism of protective action, the α2δ1-subunit of the voltage-dependent calcium channel (α2δ1-subunit) was evaluated in both sides of the L5 dorsal root ganglia (DRG). Neuropathic pain was induced in male Sprague-Dawley rats by a surgical ligation of left L5 nerve. For the ear

6
논문|인용수 6·2004
슬관절 전치환 성형술을 받는 정형외과 환자의 척추마취에서Propofol 목표 농도 조절 주입을 이용한 단계적 진정 시BIS, AEP와 진정점수의 상관관계
이상민, 강진구, 임승운, 정익수, 함태수, 김진경, 신병섭, 안현주, 윤소정

Background: We performed a prospective, randomized study to investigate the relations between BIS (bispectral index, BISTM monitor), AAI (mid-latency AEP, A-line ARX index) and depth of sedation, and assessed two different memory functions at OAA/S score 2 under spinal anesthesia. Methods: 44 ASA physical status 1-2 patients, scheduled for elective total knee replacement arthroplasty were randomly allocated to either the BIS group (22) or the AEP group (22). Under spinal anesthesia, patients we

7
논문|인용수 6·2006
두부 하강, 외회전 자세에서의 내경정맥과 경동맥의 관찰
정익수, 권민아, 황희윤, 박정헌, 여진석, 김정수, 함태수, 이상민, 조현성

Background: This study evaluated the position and relationship between the right internal jugular vein (IJV) and the surrounding external landmarks using ultrasonography. Methods: Fifty-four patients undergoing central vein access for cardiac surgery were enrolled in this study. The IJV, carotid artery (CA) and sternocleidomastoid muscle (SCM) at the cricoid cartilage level in 15o trendelenburg position with 30o head rotation were examined using a two dimensional ultrasound transducer of a TEE

8
논문|인용수 2·2007
백서의 족관절 염좌모델에서 동시에 적용한 전기침구가 염좌 통증에 미치는 효과
함태수, 조현성, 곽미숙, 이숙영

Simultaneous acupuncture to two or more acupoints has been used to improve acupuncture-induced effects in clinical practice. However, there is little evidence supporting the effects of simultaneous electroacupuncture (EA). This study examined whether simultaneous EA with 2 and 2 Hz or 2 and 100 Hz can produce synergic effects on ankle-sprained pain in rats. Methods: Ankle sprain pain was induced by manually overextending the lateral ligament of the right ankle in rats. Electrical stimulation wi

9
논문|인용수 2·2006
추간판 탈출증 환자에서 길잡이철사가 삽입된 경막외카테터를 이용한 미추경막외조영술
심우석, 김지애, 함태수, 김갑수, 조현성, 김태형, 고상욱, 이석진, 황희윤, 최수주, 김정수

=Caudal Epidural Injection with a Guidewire-Reinforced Epidural Catheter inPatients with Herniated Nucleosus PulposeJustin Sangwook Ko, M.D., Seok Jin Lee, M.D., Hee Youn Hwang, M.D., Woo Seok Sim, M.D.,Soo Joo Choi, M.D., Jie Ae Kim, M.D., Chung Su Kim, M.D., Tae Soo Hahm, M.D.,Gaab Soo Kim, M.D., Hyun Sung Cho, M.D., and Tae Hyeong Kim, M.D.

10
논문|인용수 2·2010
Unilateral massive hydrothorax in a gynecologic patient with pseudo-Meigs’ syndrome -A case report-
함태수, 함지선, 강지영

Pseudo-Meigs’ syndrome is characterized by the presence of a benign ovarian tumor associated with ascites and a right-sided hydrothorax. The major problem associated with pseudo-Meigs’ syndrome is the respiratory distress caused by a giant mass in the peritoneal space, massive ascites and pleural effusion. Even if there are no respiratory problems prior to surgery, potential respiratory dysfunction can occur during the peri-anesthetic period, leading to hypoxia, hypercapnea and respiratory acido

11
논문|인용수 1·2010
고비중 0.5% Bupivacaine의 척추마취 후에 발생된 지속적인 신경손상 -증례 보고-
함태수, 고저스틴상욱, 진현승

Persistent neurologic injury is a rare but feared complication of neuroaxial anesthesia.Local anesthetics are believed to be an important cause.A 68-year-old man with an ASA physical status of 2 was scheduled to undergo elective knee arthroplasty.He had no clinical evidence of neurological deficits before the operation. Spinal anesthesia was administered using 10 mg of 0.5% bupivacaine and 20μg of fentanyl without difficulty or complications during the procedure.On the second postoperative day,

12
논문|인용수 1·2006
백서의 족관절 염좌모델에서 전기침구에 효과적인 침구점
조현성, 양미경, 유래근, 함태수

Background: The stimulation and selection of an effective acupoint is important for producing effective analgesia in electraoacupuncture. This study examined the effect of electroacupuncture to different acupoints and investigated the effective acupoint for ankle-sprained pain in rats. Methods: A Sprain was produced by manually overextending the lateral ligament of the right ankle in rats. Electrical stimulation was delivered individually to five acupoints: bilateral Yangno (SI6s), contralater

13
논문|인용수 1·2005
수술 전 불안지수와 혈중 Potassium 농도와의 상관관계
조현성, 함태수, 서성원

Background: Patients experience preoperative anxiety which stimulates the release of catecholamines. They have influences on serum K+ level by shifting them into the intracellular space. The purpose of this study is to determine whether there is a correlation between anxiety and the serum potassium level immediately before induction of anesthesia. Methods: Thirty patients were asked about their anxiety levels at 7:00 pm of the day before surgery and immediately before induction of anesthesia: 0

14
논문|인용수 1·2011
Involuntary movements after ramosetron injection during propofol anesthesia −A case report−
김영순, 함태수, 정양훈, 이정진

We report here on a case of a female patient with involuntary movements that lasted for approximately 8 hours after being administered a single dose of ramosetron, a highly selective serotonin 5-hydroxytryptamine type 3 (5-HT3) receptor antagonist,to prevent postoperative nausea and vomiting (PONV) at the end of general anesthesia with using propofol. To the best of our knowledge, this is the first report of involuntary movement related to ramosetron. (Anesth Pain Med 2011; 6: 143∼145)

15
논문|인용수 1·2009
전기침구법
함태수

Electrical stimulation of acupoint (EA), a form of electrotherapy, involves passing an electrical current via pairs of acupuncture needles attached to a device that generates an electrical pulse. This electrical generator is used to control and adjust the stimulus parameters. EA is quite similar to traditional acupuncture in that the same points are stimulated. However, EA stimulates a larger area than a specific point. In addition, greater control of stimulus parameters is possible with EA, whi

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