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이원재 교수

Wan Jae Yi

성균관대학교 의학과 · 의학

연구실 소개

이원재 교수의 연구실은 주로 진단 영상의학과 분야에서 암 및 간담도계 질환의 조기 진단을 위한 첨단 영상 기반 기술 개발에 집중하고 있습니다. 특히 산성 병변을 정밀하게 타겟팅하는 pH 민감성 나노입자 기반 MRI 대조제 개발과 함께, 담도암의 이형성 허혈성 병변 및 간질환의 영상 소견 분석을 통해 정밀의료를 실현하고자 합니다. 또한 응급실 접근성과 환자 이동 거리의 영향 분석을 통해 의료 접근성 향상 전략을 모색하고 있습니다.

MRI 대조제산성 타겟팅담도암응급의료 접근성영상 기반 진단

연구 현황

논문 수
427
총 인용 수
13,087
최근 5년 논문
29
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
29총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
150총합
20222023202420252026

주요 논문

15
1
리뷰|인용수 143·2001
Radiologic Spectrum of Cholangiocarcinoma: Emphasis on Unusual Manifestations and Differential Diagnoses
Won Jae Lee, Hyo Keun Lim, Kyung Mi Jang, Seung H. Kim, Soon Jin Lee, Jae Hoon Lim, In Wook Choo
SJR Q1Radiographics

Most cholangiocarcinomas are ductal adenocarcinomas that arise from both intra- and extrahepatic bile duct epithelium, and their typical growth pattern can be classified as exophytic, infiltrative, polypoid, or a combination of these. Those of unusual histologic type (eg, mucin-hypersecreting cholangiocarcinoma, squamous adenocarcinoma, biliary cystadenocarcinoma, and mucinous carcinoma) show a growth pattern different from that of the typical ones (ie, ductal). Cholangiocarcinomas frequently de

SurgeryMedicine
2
논문|인용수 127·1994
Emergency Percutaneous Nephrostomy: Results and Complications
Won Jae Lee, Uresh Patel, Smita S. Patel, George Pillari
SJR Q2Journal of Vascular and Interventional RadiologyOA

PURPOSE: Percutaneous nephrostomy is a well-established standardized procedure in the management of patients with various urologic problems. The goal of this study was to evaluate the effectiveness and safety of percutaneous nephrostomy in an emergency setting. PATIENTS AND METHODS: Emergency percutaneous nephrostomy was performed in 160 patients with ages ranging from 2 to 89 years (mean, 52 years). Access to the kidney was planned and achieved with C-arm fluoroscopic guidance. RESULTS: The ini

Pulmonary and Respiratory MedicineMedicine
3
논문|인용수 116·2012
Fe3O4/MnO hybrid nanocrystals as a dual contrast agent for both T1- and T2-weighted liver MRI
Geun Ho Im, Soo Min Kim, Dong-Gyu Lee, Won Jae Lee, Jung Hee Lee, In Su Lee
SJR Q1Biomaterials
Materials ChemistryMaterials Science
4
논문|인용수 112·2012
The use of pH-sensitive positively charged polymeric micelles for protein delivery
Guanghui Gao, Min Jung Park, Yi Li, Geun Ho Im, Jaehoon Kim, Hun Nyun Kim, Won Jae Lee, Won Jae Lee, Pyoung Jeon, Oh Young Bang, Jung Hee Lee, Jung Hee Lee
SJR Q1Biomaterials
BiomaterialsMaterials Science
5
논문|인용수 107·2010
Magnetite‐Nanoparticle‐Encapsulated pH‐Responsive Polymeric Micelle as an MRI Probe for Detecting Acidic Pathologic Areas
Guanghui Gao, Geun Ho Im, Min-Sang Kim, Won Jae Lee, Won Jae Lee, Jehoon Yang, Hyesung Jeon, Jung Hee Lee, Jung Hee Lee, Doo Sung Lee
SJR Q1Small

A facile and powerful pH-responsive polymeric micelle encapsulates Fe3O4 nanoparticles as an acid-targeting MRI contrast agent for pathologic diagnosis. This MRI probe remains in a micellar state in the physiological environment whereas it can be dissolved in acidic pathological areas. More biomedical applications will be possible owing to its unique ability to target an acidic pathologic environment.

Materials ChemistryMaterials Science
6
논문|인용수 97·2010
The value of PET/CT for preoperative staging of advanced gastric cancer: Comparison with contrast-enhanced CT
Eun Young Kim, Won Jae Lee, Dongil Choi, Soon Jin Lee, Joon Young Choi, Byung‐Tae Kim, Hyung Sik Kim
SJR Q1European Journal of Radiology
Pulmonary and Respiratory MedicineMedicine
7
논문|인용수 76·2008
Detecting recurrence of gastric cancer: the value of FDG PET/CT
Min Jung Park, Won Jae Lee, Hyo Keun Lim, Ko Woon Park, Joon Young Choi, Byung‐Tae Kim
Abdominal Imaging
Pulmonary and Respiratory MedicineMedicine
8
논문|인용수 63·2013
Mn2+-doped silica nanoparticles for hepatocyte-targeted detection of liver cancer in T1-weighted MRI
Soo Min Kim, Geun Ho Im, Dong-Gyu Lee, Jung Hee Lee, Won Jae Lee, In Su Lee
SJR Q1Biomaterials
BiomaterialsMaterials Science
9
논문|인용수 58·2007
Utilization of the emergency room: impact of geographic distance
Jae Eun Lee, Jung Hye Sung, William B. Ward, Peter J. Fos, Won Jae Lee, Jae Chang Kim
SJR Q2Geospatial healthOA

The aim of this study was to estimate the distance Mississippi patients must travel to access hospital-based emergency rooms (ERs) and to determine whether an association exists between geographic distance and ER utilization. To that end, great circle distances between Census Block Group Centroid Points and 89 hospitals with emergency departments were calculated for the State of Mississippi. Data on the socio-demographic characteristics of each block group came from the 2000 US Census data. Logi

Emergency MedicineMedicine
10
논문|인용수 53·1986
Percutaneous nephrolithotomy: Analysis of 500 consecutive cases
Won Jae Lee, Arthur D. Smith, Vincent Cubelli, Frances Vernace
Urologic Radiology
Pulmonary and Respiratory MedicineMedicine
11
논문|인용수 48·2010
Differentiation of Nonneoplastic and Neoplastic Gallbladder Polyps 1 cm or Bigger With Multi-Detector Row Computed Tomography
Ko Woon Park, Seong Hyun Kim, Seong‐Ho Choi, Won Jae Lee
SJR Q3Journal of Computer Assisted Tomography

Size bigger than 1.5 cm, sessile shape, and perception on unenhanced images are the main factors that differentiate neoplastic from nonneoplastic gallbladder polyps 1 cm or bigger.

SurgeryMedicine
12
논문|인용수 47·1999
Foci of eosinophil-related necrosis in the liver: imaging findings and correlation with eosinophilia.
Won Jae Lee, Hyo Keun Lim, Jae Hoon Lim, S H Kim, Seon-Hee Choi, S J Lee
SJR Q1American Journal of Roentgenology

Foci of eosinophil-related necrosis cause focal hepatic lesions of varying size, shape, and number on helical CT and sonography. The number and extent of these foci were closely correlated to eosinophil counts in the peripheral blood.

RheumatologyMedicine
13
논문|인용수 43·1994
Emergency Percutaneous Nephrostomy: Technical Success Based on Level of Operator Experience
Won Jae Lee, David J. Mond, Mahendra P. Patel, George Pillari
SJR Q2Journal of Vascular and Interventional Radiology
Pulmonary and Respiratory MedicineMedicine
14
논문|인용수 37·1976
Mediastinal Lipomatosis in Simple Obesity
Won Jae Lee, G. A. Fattal
SJR Q1CHEST Journal
SurgeryMedicine
15
논문|인용수 35·2002
Assessment of Therapeutic Response in Hepatocellular Carcinoma Treated With Percutaneous Radio Frequency Ablation
Dongil Choi, Hyo Keun Lim, Seung Hoon Kim, Won Jae Lee, Hyun‐Jung Jang, Hana Kim, Soon Jin Lee, Jae Hoon Lim
SJR Q2Journal of Ultrasound in Medicine

OBJECTIVE: To compare the results of multiphase helical computed tomography and power Doppler ultrasonography with a microbubble contrast agent in the assessment of the therapeutic response to radio frequency ablation in hepatocellular carcinoma. METHODS: In 66 patients with 73 nodular hepatocellular carcinomas ranging from 1.0 to 4.0 cm (mean, 2.6 cm) in diameter, contrast-enhanced power Doppler ultrasonography was performed after intravenous bolus injection of a galactose-based microbubble con

HepatologyMedicine

대표 연구 분야

HepatologySurgeryRadiology, Nuclear Medicine and ImagingEpidemiologyOncologyPulmonary and Respiratory Medicine

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