표원경 교수
Won Kyung Pyo
연세대학교 흉부외과 · 의학
연구실 소개
표원경 교수의 연구실은 심장 밸브 질환, 특히 대동맥판막 협심증과 감염성 endocarditis에 중점을 두고 있으며, 수술적 치료와 항생제 요법의 최적화를 위한 임상 연구 및 생체역학적 분석을 수행하고 있습니다. 특히 투석이 필요한 환자나 당뇨병 환자와 같은 고위험군에서의 감염성 심내막염 발생 위험과 운동량의 관계, 그리고 생체재료 기반 심장판막의 내구성에 대한 기계적 분석까지 다각도로 연구를 확장하고 있습니다. 최근에는 TAVI와 SAVR의 임상적 결과 비교 및 장기적 생존율 분석을 통해 최적의 수술 전략을 모색하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15PVE carried significant perioperative risks, and was an independent risk factor of overall mortality.
Appropriate postoperative antibiotic treatment in patients with infective endocarditis (IE) reduces the risks of recurrence and mortality. However, concerns about adverse drug reactions arise due to prolonged antibiotic usage. Therefore, we compared the recurrence and mortality rates according to the duration of postoperative antibiotic therapy in patients with IE. From 2005 to 2017, we retrospectively reviewed 416 patients with IE treated at a tertiary hospital in South Korea; among these, 216
Mini-access open arch repair is technically feasible and achieved excellent early outcomes.
Patients with diabetes mellitus (DM) are at a higher risk of infectious diseases, and exercise is an important treatment modality for DM. Despite their susceptibility to infection in diabetic patients, the association between the amount of physical activity and the incidence of infective endocarditis (IE) is unclear. We attempted to demonstrate risk reduction by physical activity in diabetic patients with IE. From the National Health Insurance database, patients with DM were verified, and the in
In this propensity-matched cohort of patients who underwent AVR for severe AS, we did not detect significant differences in the rates of the primary composite of death, stroke, or rehospitalization at 12 months when comparing RD-AVR with SAVR and TAVR. Because the study was underpowered, the results should be considered as hypothesis generating highlighting the need for further research. (ASAN Medical Center Aortic Valve Replacement Registry [ASAN-AVR]; NCT03298178).
Since the introduction of transcatheter aortic valve (AV) implantation as a viable option, surgical bioprosthetic AVs have recently started incorporating shorter struts considering future valve-in-valve procedures. However, the effect of leaflet coaptation geometry on the longevity of these valves remains unexplored. To address this gap, we performed a finite element analysis on bioprosthetic AVs with varying strut heights using a two-way fluid-structure interaction method. To establish a baseli
Congenital atresia of the left main coronary artery (LMCA) is an extremely rare coronary anomaly that necessitates surgical correction. Patients with LMCA atresia may have various clinical symptoms, which are determined by the degree of collateral vessel development from the right coronary system, the metabolic demands of the heart, and concomitant mitral insufficiency caused by myocardial ischemia. Unlike in adults, there are limited surgical options for coronary artery disease in children. Her
Central MessageA 3-dimensional printing model may be an important guiding tool for establishing surgical planning in complex cardiac tumors.See Commentaries on pages 41 and 43. A 3-dimensional printing model may be an important guiding tool for establishing surgical planning in complex cardiac tumors. See Commentaries on pages 41 and 43. The primary cardiac tumor is extremely rare, constituting 0.3% to 0.7% of all cardiac tumors.1Castello J. Silvay G. Characterization and management of cardiac t
BACKGROUNDS: The association between weight change in patients with diabetes, and the development of infective endocarditis (IE) has never been studied. Therefore, we evaluated the associations of weight changes in patients with diabetes with the development of IE. METHODS: In this Korean population-based cohort study, we included patients with diabetes aged ≥20 years who underwent health screenings twice in a 2-year interval between 2009 and 2012. Patients were categorized into five groups acco
Diabetic patients may require rigorous blood pressure control and simultaneous avoidance of excessive weight loss to prevent IE.
As mediastinal sarcomas commonly present as large tumors invading adjacent vital structures, complete resection is frequently challenging. For such tumors, aggressive surgical strategies, such as the resection and reconstruction of the invaded vital structures under cardiopulmonary bypass, may be required to achieve complete resection and to improve survival. Herein, we report a case of recurrent mediastinal sarcoma invading the aortic arch and arch vessels that was successfully removed by total
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