장원진 교수
Wonjin Jang
서울대학교 소아과 · 의학
연구실 소개
장원진 교수의 연구실은 소아 환자의 조기 위험도 평가 및 중환자 관리의 정밀화를 목표로 하며, 특히 소아 중환자에서의 퇴행성 상태 조기 탐지, 안정적 진통 및 수면 조절을 위한 인공지능 기반 모델 개발, 그리고 신생아 및 소아에서의 심각한 호흡기 합병증에 대한 생명유지 치료 전략을 중심으로 연구를 진행하고 있습니다. 특히 심전도 파라미터와 생체신호를 기반으로 한 딥러닝 기반 예측 모델 개발과 함께, ECMO를 활용한 만성 폐질환 및 급성 호흡부전의 치료 사례 분석을 통해 임상적 실천에 기여하고자 합니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
6Early identification of clinical deterioration in hospitalized children is essential to improve outcomes and prevent critical events. Over the past two decades, structured approaches such as pediatric early warning scores and rapid response systems have provided a framework for systematic risk detection in general wards. More recently, artificial intelligence and continuous monitoring technologies have begun to transform this field, offering the potential for more timely and accurate recognition
Background Allogeneic HSCT may improve survival in pediatric ALL patients who relapse. In this study, we analyzed the outcome and prognostic factors of 62 ALL patients (35 male, 56.5%) who received allogeneic HSCT in second complete remission (CR) at our institution between April 1st 2009 and December 31st 2019. Methods The median time from diagnosis to relapse was 35.1 months (range, 6.0‒113.6 mo). Fifty-three patients (85.5%) experienced bone marrow relapse only. The number of patients who rec
Background:Optimal sedation assessment in critically ill children remains challenging due to the subjective nature of behavioral scales and intermittent evaluation schedules. This study aimed to develop a deep learning model based on heart rate variability (HRV) parameters and vital signs to predict effective and safe sedation levels in pediatric patients.Methods: This retrospective cross-sectional study was conducted in a pediatric intensive care unit at a tertiary children’s hospital. We devel
Background: Various rapid response systems have been developed to detect clinical deterioration in patients. Few studies have evaluated single-parameter systems in children compared to scoring systems. Therefore, in this study we evaluated a single-parameter system called the acute response system (ARS).Methods: This retrospective study was performed at a tertiary children’s hospital. Patients under 18 years old admitted from January 2012 to August 2023 were enrolled. ARS parameters such as syst
Bronchopulmonary dysplasia (BPD) and pulmonary hypertension (PH) are potentially fatal complications in prematurely born infants. Extracorporeal membrane oxygenation (ECMO) may be a life-saving option for managing infants with BPD and PH. We present 2 patients who were successfully weaned off mechanical ventilators (MVs) through the application of ECMO. The patients were transferred to our institution after receiving MV care for 8 and 10 months, respectively, for BPD and PH. We were able to remo
Laundry detergent pod (LDP) exposure has been reported to be fatal in children younger than 2 years, leading to respiratory or central nervous system depression. While gastrointestinal irritation is the most common symptom, there are reported cases of severe acidosis with respiratory depression or pneumonia, resulting in mortality. To our best knowledge, there is no report on a case of LDP exposure presenting with acute respiratory distress syndrome requiring extracorporeal membrane oxygenation
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