최의경 교수

Usefulness of Early Neurodevelopmental Testing

Objective: Preterm births in the late preterm period comprise more than half of all preterm births. However, perinatal outcome evaluation between singleton and multiple pregnancies is limited. This study aimed to compare the perinatal outcomes of preterm pre-labor rupture of membranes (PPROM) between twin and singleton pregnancies at 34 weeks to 36 weeks and 6 days. Methods: This retrospective case-control study included women with preterm births at the Tertiary Hospital between July 2006 and De

Purpose: Neutrophil gelatinase-associated lipocalin (NGAL) has been identified as an early marker of acute kidney injury (AKI). This study was designed to evaluate the clinical utility of the rapid plasma NGAL assay for diagnosing AKI in critically ill newborn infants in the neonatal intensive care unit (NICU). Methods: The medical records of 178 critically ill newborn infants >34 weeks of gestational age who underwent plasma NGAL measurement during the first week of life in the Korea University

Umbilical venous catheters (UVCs) are frequently used in extremely low birth weight (ELBW) infants for intravenous access. It is important to position correctly to prevent complications, including arrhythmia, pleural effusion, pericardial effusion, and cardiac tamponade. Pericardial effusion remains asymptomatic in the early stages and cardiac tamponade suddenly appears as a cardiac arrest. The authors report a case of successful management of malpositioned UVC-related cardiac tamponade in an EL

Trans-placental neonatal human immunodeficiency virus (HIV) infection is common in Africa; however, it is not yet reported in the Republic of Korea. With the increasing incidence of HIV infection, especially in the reproductive age group, the risk of the vertical transmission of HIV is also increasing. We report the first case of HIV infection acquired in-utero in a newborn in Korea. The baby is growing well with normal development.

Respiratory distress syndrome (RDS) is the leading cause of neonatal respiratory morbidity and mortality. Advancements in neonatal care, along with extended insurance coverage, have resulted in increased utilization of surfactant replacement therapy (SRT) for RDS. This has contributed to a decrease in neonatal mortality. The primary mode of respiratory support in infants with RDS has dramatically changed over the last decades, transitioning from invasive to noninvasive support. Therefore, less i

Objectives: This study compared the nutritional intakes of early and late preterm infants in a neonatal intensive care unit (NICU) and at home. The dietary problems and the need for community care services for premature infants were further investigated. Methods: This is a cross-sectional and descriptive study on 125 preterm infants and their parents (Early preterm n = 70, Late preterm n = 55). The data were collected by surveying the parents of preterm infants and from hospital medical records.

Purpose: To identify the significance of the 12-month developmental assessment in high-risk neonates by comparing their 12 month and later childhood...

목적: 극소 저체중 출생아에서 갑상샘 저하증이 생후 초기 식이 진행에 미치는 영향에 대해 연구하였다. 방법: 2007년 1월부터 2009년 8월까지 서울대학교 어린이병원에 입원한 극소 저체중 출생아 중 갑상샘 저하증으로 진단받고 갑상샘 호르몬을 투여 받은 14명을 대상으로 한 후향적 사례 조절 연구로 체중 증가 정도, 완전 장관 영양에 도달한 날, 위 내 수유 잔류량의 빈도와 중심 정맥 도관의 사용 일수를 포함한 병력을 조사하여 갑상샘 기능이 정상이면서 재태 연령과 출생 체중을 짝지은 대조군 14명과 비교하였다. 결과: 완전 장관 영양에 도달하는데 걸리는 기간은 두 군간에 유의한 차이는 없었으나 생후 14일까지 평균 수유량은 갑상샘 저하증군이 더 적었으며[14.7 (0.5-84.0) vs 49.3 (8.2-98.1) mL/kg/day, P=0.041], 위 내 수유 잔류량의 횟수도 더빈번하게[10.8 (1.0-51.0) vs 5.9 (0-27.0)회, P=0.036] 나타났다. 또한

Objective: The different patterns of ductal shunt flow by Doppler echocardiography are useful for the diagnosis and prediction of risk of hemodynamically significant patent ductus arteriosus (PDA), especially growing or pulsatile patterns. We examined whether the ductal flow patterns might represent a reliable guide for PDA management in preterm infants with respiratory distress, using a comparison of traditional echocardiographic parameters. Methods: Thirty-one preterm infants with gestational

Purpose: This study was performed to determine the clinical features of full-term infants with hypoxemia detected by pulse oximetry and to establish the diagnosis of critical congenital heart disease (CCHD). Methods: We retrospectively reviewed the medical records of neonates who had been admitted to the neonatal intensive care unit within 2 weeks of birth at Korea University Ansan Hospital between January 2013 and October 2017 (n=450). We classified these neonates based on the presence of hypox

이 연구는 연구실안전관리사 국가자격종목 개발을 위해 데이컴(DACUM: Developing A Curriculum) 기 법을 활용하여 연구실안전관리사의 직무를 분석하는데 목적이 있다. 이를 위해 데이컴 분석가(facilitator) 1명, 산업계 현업 내용전문가로 이루어진 데이컴 패널(panel) 11명, 데이컴 실무자(recorder) 1명으로 데 이컴 위원회를 구성하여 직무분석을 실시하여 연구실안전관리사의 직무정의, 직무모형, 직업명세서, 직무명 세서, 작업명세서 등을 도출하고, 응시자격, 검정기준, 시험과목, 검정방법 등의 구성 내용을 추출하였다. 주 요 연구결과는 다음과 같다. 첫째, 직무모형에 분석된 연구실안전관리사의 책무는 연구실 안전관리규정 제·개정, 연구실 안전관리 계획 및 시스템 구축, 연구실 안전교육, 연구실 안전점검 및 정밀안전진단, 연구 실 안전관리, 연구실 안전환경개선, 사전유해인자위험분석, 연구실 보건·환경관리, 사고관리, 안전관리 우 수연구실 인증으로 구성

Objective: We investigated the usefulness of the plasma B-type natriuretic peptide (BNP) levels measured 24 hours after the last ibuprofen dose in predicting the need for an additional dose to prevent the recurrence of symptomatic patent ductus arteriosus (PDA) following completion of the planned pharmacological treatment. Methods: Seventy-one preterm infants with hemodynamically significant (hs) PDA, whose plasma BNP levels were measured just before and 24 hours after the last ibuprofen dose we