편욱범 교수
Wook-beom Pyeon
이화여자대학교 의학과 · 의학
연구실 소개
편욱범 교수의 연구실은 고혈압 및 심혈관계 질환의 예방과 정책적 접근을 중심으로, 약물 치료의 장기적 영향과 환경 요인의 심장병 유발 메커니즘을 분석합니다. 특히 항고혈압제의 암 유발 위험, 레이저 영상에서의 심장조직 변화, 기후 환경 요인과 심근경색의 연관성 등 실생활 데이터 기반의 대규모 인구 연구를 수행합니다. 고령 환자에서의 약물 부작용과 감염 시 혈압 조절의 역할 등 임상적 실무에 밀접한 연구를 지속하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15LGE confined to the RVIP among NICM patients did not significantly increase the risk of adverse cardiac events, and also showed a better outcome than the same extent of LGE located in the LV. Identification of this unique LGE distribution may help refine the current risk stratification.
We sought to assess the association between common antihypertensive drugs and the risk of incident cancer in treated hypertensive patients. Using the Korean National Health Insurance Service database, the risk of cancer incidence was analyzed in patients with hypertension who were initially free of cancer and used the following antihypertensive drug classes: Angiotensin-converting enzyme inhibitors (ACEIs); angiotensin receptor blockers (ARBs); beta blockers (BBs); calcium channel blockers (CCBs
Antihypertensive drugs are one of the most widely used pharmacologic agent in the world and it is predominantly used in the elderly subjects. Pneumonia is the most common cause of death in the extremely old subject. During infection and its complication such as sepsis, hypotension could be exacerbated by antihypertensive drugs because homeostasis mechanisms such as sodium balance, renin angiotensin aldosterone system and/or sympathetic nervous system can be mitigated by antihypertensive drug the
BACKGROUND/AIM: Previous studies have suggested that the short-term ambient air pollution and temperature are associated with myocardial infarction. In this study, we aimed to conduct a time-series analysis to assess the impact of fine particulate matter (PM2.5) and temperature on acute myocardial infarction (AMI) among adults over 20 years of age in Korea by using the data from the Korean National Health Information Database (KNHID). METHODS: The daily data of 192,567 AMI cases in Seoul were co
Background It is unclear what office blood pressure (BP) is the optimal treatment target range in patients with hypertension. Methods and Results Using the Korean National Health Insurance Service database, we extracted the data on 479 359 patients with hypertension with available BP measurements and no history of cardiovascular events from 2002 to 2011. The study end point was major cardiovascular events (MACE), a composite of cardiovascular death, myocardial infarction, or stroke. This cohort
Takayasu's arteritis is a chronic inflammatory disease of unknown etiology involving the aorta, major branches of aorta, and pulmonary arteries and leads either stenosis and occlusion of the involved artery or aneurysm formation or both.The clinical course and prognosis are variable according to two major prognostic factors, ie, complications and the pattern of the past clinical course, as well as by ESR.Though the aggressive medical and surgical treatment are required for patients with a major
More women have died from cardiovascular disease since middle 1980’s than men due to the women’s older age and multiple comorbid conditions. Additionally, women with acute coronary syndrome have worse outcomes, including sudden cardiac death and death before arriving to the hospital, due to the women’s atypical symptoms and the delayed diagnosis and treatment. There are many reports on the gender-specific differences in the pathophysiology of ischemic heart disease. In addition to the previous r
There is a tremendous amount of evidence about the beneficial roles of statins, as related to primary and secondary prevention, for patients with ischemic heart disease. Many cardiologists are prescribing these drugs to their patients regardless of the left ventricular systolic function, and especially for patients with old myocardial infarction. After the report on the post-hoc analysis of the Scandinavian Simvastatin Survival Study, there have been many reports about the roles of statins for t
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