박양진 교수
Yangjin Park
성균관대학교 의학과 · 의학
연구실 소개
박양진 교수의 연구실은 대동맥aneurysm, 혈관성 혼란(데릴리움), 혈관 수술 후 합병증 등 정형외과 및 일반외과 분야의 혈관 질환에 중점을 두고 있습니다. 특히 복합적이고 위험도가 높은 대동맥aneurysm의 진단, 치료 전략 및 재발 예방에 관한 연구를 지속적으로 수행하고 있으며, 신경섬유종증과 같은 희귀 유전성 혈관질환의 임상적 특성과 병리학적 소견을 분석하는 데에도 기여하고 있습니다. 또한 혈관 수축성 병변의 병리 생물학적 기전을 규명하고, 이의 치료를 위한 약물(예: 이마티닙, 라파미신)의 효과를 실험적으로 평가하는 기초 연구도 진행 중입니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15Delirium is a common complication of vascular surgery. The protective effect of preoperative statins on delirium after vascular surgery is controversial. The authors hypothesized that preoperative statin administration would decrease the incidence of delirium after vascular surgery. From May 2010 to May 2015, 1,132 patients underwent vascular surgery. Postoperative delirium was diagnosed from patients' medical records. The incidence of delirium was 11.5%. The preoperative statin exposure was not
As a curative surgery for ACD, vessel excision with interposition grafting is a better strategy to prevent recurrence than simple cyst excision alone.
Neurofibromatosis type I (NF-1) is a rare autosomal dominant genetic disorder occurring in 1 in 3,000 individuals. Vasculopathy is a rarely reported finding in patients with NF-1. Here, we report a case of recurrent aortic pseudoaneurysm after endovascular aneurysm repair in a 49-year-old male patient with NF-1. On the sixth postoperative day following a successful open surgical repair of an aortic pseudoaneurysm, he developed hemoperitoneum due to a delayed rupture of the mesenteric artery bran
Purpose: To know the current trend of the annual number of AAA patients in Korea and treatment modality, we attempted to investigate the numbers of patients diagnosed with AAA and the number of patients who underwent open or endovascular treatment of AAA in Korea during the last 6 years. Methods: To investigate the number of AAA patients, we searched for ruptured AAA and AAA without description of rupture disease from the database of Health Insurance Reimbursement Association (HIRA) by searching
Purpose: To know the current trend of the annual number of AAA patients in Korea and treatment modality, we attempted to investigate the numbers of patients diagnosed with AAA and the number of patients who underwent open or endovascular treatment of AAA in Korea during the last 6 years. Methods: To investigate the number of AAA patients, we searched for ruptured AAA and AAA without description of rupture disease from the database of Health Insurance Reimbursement Association (HIRA) by searching
Purpose: Intimal hyperplasia (IH) is the main cause of restenosis or occlusion after vascular procedures. Imatinib mesylate and rapamycin are known to prevent IH. The purpose of this study was to evaluate the effect of these drugs on the regression of preformed IH in rat carotid injury model. Methods: IH was established in rat carotid arteries using a balloon catheter. The drug effects were assessed in vitro on proliferation, migration, and apoptosis of vascular smooth muscle cells (VSMC) in the
Combined treatment of with imatinib and rapamycin induced reduction of cell mass in preformed intimal hyperplasia, but failed to induce regression of intimal mass in this short-term medication study. Further studies will be needed with additional strategies of inducing lysis of the extracellular matrix.
Objective Limb salvage is an important concern following complete oncologic resection for extremity soft tissue sarcoma (STS). Vascular reconstruction is essential for limb salvage. The purpose of this study was to evaluate the outcomes of vascular reconstruction in patients with extremity STS. Methods This is a retrospective, multi-center, case series of consecutive patients who underwent vascular reconstruction during extremity STS resection at 2 major centers in Korea. Demographics, reconstru
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