김용휘 교수
Yong Hwy Kim
서울대학교 신경외과 · 의학
연구실 소개
김용휘 교수의 연구실은 뇌신경외과 분야에서 주로 활동하며, 뇌간 및 척추기저부에 위치한 난치성 종양, 특히 척추기저부 종양(CNP), 뇌간 림프종, 척추기저부 악성 종양 등에 대한 미세외과적 및 내시경적 접근법을 중심으로 연구를 진행하고 있습니다. 특히 뇌신경통, 뇌종양의 방사선외과적 치료(라우팅 레이저 수술, Gamma Knife) 및 뇌전이성 종양의 다학제 치료 전략 개발에 초점을 맞추고 있으며, 환자의 삶의 질 향상과 장기적인 신경학적 예후 개선을 목표로 하고 있습니다. 최근에는 뇌종양의 분자표적치료 및 레지온 기반 치료 전략에 대한 기초 연구도 함께 진행하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15The long-term clinical outcomes of CN after multimodal treatment seem to be excellent. Our study suggests that treatment strategies for CN should focus on the patient's quality of life, as well as on tumor control, because of the benign nature of CN.
OBJECTIVE The endoscopic endonasal approach for treating primary skull base malignancies involving the clivus is a formidable task. The authors hypothesized that tumor involvement of nearby critical anatomical structures creates hurdles to endoscopic gross-total resection (GTR). The aim of this study was to retrospectively review the clinical outcomes of patients who underwent an endoscopic endonasal approach to treat primary malignancies involving the clivus and to analyze prognostic factors fo
OBJECTIVE: In order to assess the effect of raising gamma knife radiosurgery (GKS) doses from 80 to 85 Gy for the treatment of trigeminal neuralgia (TN), the authors analyzed the outcomes of GKS in each group. PATIENTS AND METHODS: The authors retrospectively collected follow-up data of 104 GKS procedures conducted for TN. Doses of 80 and 85 Gy were prescribed for 60 and 44 patients, respectively. The target was 2-4 mm anterior to the junction of the trigeminal nerve and pons. Outcomes were quan
Papillary tumor of the pineal region (PTPR) is a recently recognized and rare pineal tumor, presenting as a solitary mass with or without hydrocephalus. Here, we report a case of c-Kit expressing PTPR with leptomeningeal seeding. A 39-year-old woman presented with a 1-month history of headache and decreased visual acuity. MRI showed a large, 4 cm-diameter solid and cystic enhancing mass at the pineal region with associated ventriculomegaly. Smaller nodular lesions were also found at the pituitar
Renal cell carcinoma (RCC) is one of primary cancers which metastasis to the brain frequently, although RCC accounts for only 1% of all cancer. The metastatic tumor from RCC has the propensity of intratumoral hemorrhage and relatively massive surrounding edema compared with other metastatic tumors. These characteristics make an emphasis on the surgical resection in the management of metastatic tumor. However, the surgery is not always possible due to the characteristics of tumor and patient. The
Short-term VD secondary to the surgical insult and the recurrence of the tumor were strong predictors of long-term visual outcomes after surgical treatment for CRP. STR alone may be an ineffective strategy for achieving tumor control and optimal visual outcomes in patients with CRP.
The endoscopic endonasal approach (EEA) has been popularized in adults and has been applied to an expanding range of surgical modules and indications in this population. However, its clinical application in pediatric neurosurgery has been impeded by the differences in anatomical features and the relatively low incidence of diseases to which it is applicable. In this review article, we mainly discuss the surgical indications, feasibility, and complications of EEA for suprasellar lesions in childr
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