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이용상 교수

Yong Sang Lee

연세대학교 외과 · 의학

연구실 소개

이용상 교수의 연구실은 주로 갑상선암의 수술적 치료 전략과 병변의 생물학적 특성에 초점을 맞추고 있습니다. 특히 소형 갑상선암에서의 림프절 확장 절제의 임상적 유의성, 갑상선암의 이환율과 병행되는 잠재성 암의 특성 비교, 그리고 고도로 악성도가 높은 낭성 갑상선암의 표적 치료제 개발까지 다각도로 연구를 진행하고 있습니다. 특히 수술 범위와 합병증, 호르몬 이상 반응, 암세포의 약물 내성 메커니즘 등 임상적 실용성을 기반으로 한 정밀의료 전략 수립이 핵심 목표입니다.

갑상선암수술 범위림프절 절제약물 내성소형 갑상선암

연구 현황

논문 수
412
총 인용 수
5,420
최근 5년 논문
51
주요 분야
의학

연구 성과 추이

표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.

5개년 연도별 논문 게재 수
51총합
2022
2023
2024
2025
2026
5개년 연도별 피인용 수
203총합
20222023202420252026

주요 논문

15
1
논문|인용수 159·2010
Postoperative Complications of Thyroid Cancer in a Single Center Experience
Yong Sang Lee, Kee‐Hyun Nam, Woong Youn Chung, Hang‐Seok Chang, Cheong Soo Park
SJR Q2Journal of Korean Medical ScienceOA

The aim of this study was to investigate the complications following surgical treatment of thyroid cancer and the association between the extent of surgery and complication rates. A total of 2,636 patients who underwent surgery due to thyroid cancer were retrospectively reviewed to identify surgical complications. Complication rates were assessed according to the extent of surgery, which was classified as follows; less-than-total thyroidectomy with central compartment node dissection (CCND) (Gro

SurgeryMedicine
2
논문|인용수 139·2007
Extent of Routine Central Lymph Node Dissection With Small Papillary Thyroid Carcinoma
Yong Sang Lee, Seok Won Kim, Sun Wook Kim, Seok Ki Kim, Han‐Sung Kang, Eun Sook Lee, Ki‐Wook Chung
SJR Q1World Journal of Surgery

The indications for and extent of routine lymph node dissection in patients with papillary thyroid carcinoma (PTC) are unclear. The aim of this study was to investigate the association between the extent of central lymph node dissection (CLND) and the therapeutic effects and potential risks in patients with a small PTC. A total of 103 patients with a PTC <2 cm who underwent total thyroidectomy with routine CLND were divided into those who underwent routine bilateral CLND (group I) and those with

Endocrinology, Diabetes and MetabolismMedicine
3
논문|인용수 72·2009
Papillary Carcinoma Located in the Thyroid Isthmus
Yong Sang Lee, Jong Ju Jeong, Kee‐Hyun Nam, Woong Youn Chung, Hang‐Seok Chang, Cheong Soo Park
SJR Q1World Journal of SurgeryOA

BACKGROUND: The purpose of the present study was to evaluate the clinicopathologic characteristics and short-term outcomes of papillary thyroid carcinomas (PTC) located in the isthmus compared to tumors located in other thyroid regions, and to use those findings to establish a surgical strategy for treating these tumors. PATIENTS AND METHODS: Thyroidectomy was performed in 1,973 thyroid cancer patients in our hospital between January 2006 and December 2007. The patients were analyzed in two grou

Endocrinology, Diabetes and MetabolismMedicine
4
논문|인용수 51·2015
Some Elements in Thyroid Tissue are Associated with More Advanced Stage of Thyroid Cancer in Korean Women
Hye-Kyung Chung, Ji Sun Nam, Chul Woo Ahn, Yong Sang Lee, Kyung Rae Kim
SJR Q1Biological Trace Element ResearchOA
Health, Toxicology and MutagenesisEnvironmental Science
5
리뷰|인용수 49·2014
Papillary Thyroid Microcarcinomas Are Different from Latent Papillary Thyroid Carcinomas at Autopsy
Yong Sang Lee, Hyunsun Lim, Hang‐Seok Chang, Cheong Soo Park
SJR Q2Journal of Korean Medical ScienceOA

The aim of this study was to review the literature of latent papillary thyroid carcinomas (PTCs) discovered at autopsy and describe the available pathologic and demographic differences from a group of papillary thyroid microcarcinomas (PTMCs) the reported in a previous publication. We searched the PubMed for published articles describing latent thyroid carcinomas detected at autopsy. Meta-analysis was performed to identify differences between the clinicopathologic features of PTMCs analyzed prev

Endocrinology, Diabetes and MetabolismMedicine
6
논문|인용수 44·2018
Anti-cancer Effects of HNHA and Lenvatinib by the Suppression of EMT-Mediated Drug Resistance in Cancer Stem Cells
Yong Sang Lee, Seok‐Mo Kim, Bup‐Woo Kim, Ho Jin Chang, Soo Young Kim, Cheong Soo Park, Ki Cheong Park, Hang‐Seok Chang
SJR Q1NeoplasiaOA

Anaplastic thyroid cancer (ATC) constitutes less than 2% of total thyroid cancers but accounts for 20-40% of thyroid cancer-related deaths. Cancer stem cell drug resistance represents a primary factor hindering treatment. This study aimed to develop targeted agents against thyroid malignancy, focusing on individual and synergistic effects of HNHA (histone deacetylase), lenvatinib (FGFR), and sorafenib (tyrosine kinase) inhibitors. Patients with biochemically and histologically proven papillary t

Endocrinology, Diabetes and MetabolismMedicine
7
리뷰|인용수 37·2022
Aggressive Subtypes of Papillary Thyroid Carcinoma Smaller Than 1 cm
Jin Seok Lee, Jun Sung Lee, Hyeok Jun Yun, Seok‐Mo Kim, Hojin Chang, Yong Sang Lee, Hang‐Seok Chang, Cheong Soo Park
SJR Q1The Journal of Clinical Endocrinology & MetabolismOA

CONTEXT: Tumor size is important in determining the range of surgery in papillary thyroid carcinomas (PTCs), especially those smaller than 1 cm. OBJECTIVE: We aimed to analyze the features of small PTCs with aggressive subtypes based on histological characteristics. METHODS: In this retrospective study, we reviewed the medical records of 11 570 patients with PTCs smaller than or equal to 1 cm who underwent thyroidectomy between January 2009 and December 2016. Aggressive subtypes included diffuse

Endocrinology, Diabetes and MetabolismMedicine
8
논문|인용수 37·2020
Thyroid Hormone Supplementation Therapy for Differentiated Thyroid Cancer After Lobectomy: 5 Years of Follow-Up
Soo Young Kim, Hee Jun Kim, Seok‐Mo Kim, Hojin Chang, Yong Sang Lee, Hang‐Seok Chang, Cheong Soo Park
SJR Q1Frontiers in EndocrinologyOA

<b>Background:</b> Lobectomy with preservation of the contralateral lobe has already become the most preferred surgical method for patients with low-risk thyroid cancer. The incidence of and risk factors for the development of hypothyroidism after lobectomy for thyroid cancer remains unclear. The previous practice of levothyroxine supplementation post-thyroidectomy, to bring about thyroid stimulating hormone (TSH) suppression, had some serious side effects. This study aimed to evaluate the incid

Endocrinology, Diabetes and MetabolismMedicine
9
논문|인용수 34·2010
Adrenal Injury Following Blunt Abdominal Trauma
Yong Sang Lee, Jong Ju Jeong, Kee‐Hyun Nam, Woong Youn Chung, Hang‐Seok Chang, Cheong Soo Park
SJR Q1World Journal of SurgeryOA

BACKGROUND: Adrenal injury secondary to abdominal trauma is quite rare because the adrenal gland is located deep in the retroperitoneum and is well cushioned by surrounding soft tissues. This report presents our experiences of managing patients with adrenal injury following abdominal blunt trauma. METHODS: The medical records of 11 patients who had been treated for adrenal gland injury between January 1998 and June 2009 were retrospectively reviewed. RESULTS: Of the 11 patients, nine were male a

SurgeryMedicine
10
논문|인용수 32·2008
Soft Tissue Implantation of Thyroid Adenomatous Hyperplasia after Endoscopic Thyroid Surgery
Yong Sang Lee, Ji‐Sup Yun, Jong Ju Jeong, Kee‐Hyun Nam, Woong Youn Chung, Cheong Soo Park
SJR Q1ThyroidOA
SurgeryMedicine
11
논문|인용수 30·2012
Factors predisposing to chyle leakage following thyroid cancer surgery without lateral neck dissection
Yong Sang Lee, Bup‐Woo Kim, Hang‐Seok Chang, Cheong Soo Park
SJR Q1Head & NeckOA

BACKGROUND: The aims of this study were to assess the clinicopathologic features of patients with chyle leakage following thyroid cancer surgery without lateral neck dissection and to evaluate the factors associated with chyle leakage. METHODS: Of 3137 patients who underwent thyroid surgery between January 2006 and December 2007, 2314 patients (73.8%) satisfied our inclusion criteria. Patients were divided into those with (group I, n = 14) and without (group II, n = 2300) chyle leakage. RESULTS:

SurgeryMedicine
12
논문|인용수 30·2010
Parathyroid carcinoma: a 16-year experience in a single institution
Yong Sang Lee, Soon Won Hong, Jong Ju Jeong, Kee‐Hyun Nam, Woong Youn Chung, Hang‐Seok Chang, Cheong Soo Park
SJR Q2Endocrine JournalOA

INTRODUCTION: This study aims to describe our experiences of parathyroid carcinoma. MATERIALS AND METHODS: The data of clinicopathological features, surgical treatment and outcomes of seven cases of parathyroid carcinoma among 171 patients who underwent surgery for primary hyperparathyroidism over a 16-year period were analyzed. RESULTS: The major symptoms at the diagnosis included a neck mass in three cases and multiple bone pain in five. Two patients were asymptomatic. No remarkable increases

NephrologyMedicine
13
논문|인용수 27·2023
Primary thyroid lymphoma: A single-center experience
Jin Seok Lee, Su‐Jin Shin, Hyeok Jun Yun, Seok‐Mo Kim, Hojin Chang, Yong Sang Lee, Hang‐Seok Chang
SJR Q1Frontiers in EndocrinologyOA

Background: Primary thyroid lymphoma (PTL) is a very rare entity accounting for 5% of all thyroid malignancies and less than 2% of lymphomas. PTLs are classified as non-Hodgkin's B-cell lymphomas in the majority of cases, although Hodgkin's lymphoma of the thyroid has also been identified. This study aimed to identify the clinical, biochemical, and pathological features of primary thyroid lymphomas. Methods: From January 2008 to December 2020, data from patients diagnosed with PTL treated at the

Endocrinology, Diabetes and MetabolismMedicine
14
논문|인용수 25·2011
Computed Tomography Is Useful for Preoperative Identification of Nonrecurrent Laryngeal Nerve in Thyroid Cancer Patients
Yong Sang Lee, Eun Ju Son, Hang‐Seok Chang, Woong Youn Chung, Kee‐Hyun Nam, Cheong Soo Park
SJR Q1OtolaryngologyOA

OBJECTIVE: Nonrecurrent laryngeal nerve (NRLN) is a risk factor for nerve injury during thyroid or parathyroid surgery and is usually associated with vascular anomalies. This study investigated the usefulness of computed tomography (CT) scans for preoperative identification of NRLN in thyroid cancer patients. STUDY DESIGN: Case series with chart review. SETTING: Academic university hospital. SUBJECTS AND METHODS: Of the 6546 patients, 20 (0.3%) were intraoperatively identified with NRLN, and the

SurgeryMedicine
15
논문|인용수 24·2021
Serum Calcitonin-Negative Medullary Thyroid Carcinoma: A Case Series of 19 Patients in a Single Center
Sun Jung Kim, Hyeok Jun Yun, Su‐Jin Shin, Yong Sang Lee, Hang‐Seok Chang
SJR Q1Frontiers in EndocrinologyOA

Introduction: Medullary thyroid carcinoma (MTC) is a rare cancer that accounts for 5% of thyroid cancers. Serum calcitonin is a good biomarker for MTC, which is used for diagnosis, prognosis, and monitoring of recurrence. Calcitonin-negative MTC (CNMTC) is rare but confounds diagnostic and prognostic directions. This study introduces 19 cases of CNMTC in a single center. Method: From 2002 March to 2020 July, more than 76,500 patients had undergone thyroid surgery due to thyroid cancer at the Sev

Endocrinology, Diabetes and MetabolismMedicine

대표 연구 분야

Endocrinology, Diabetes and MetabolismAerospace EngineeringSurgeryStrategy and ManagementCivil and Structural EngineeringOncology

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