임용택 교수

Conjugated polymer nanoparticles were successfully capped with a commercially available triblock copolymer Pluronic F127® to form stable nanoparticles with the potential for photodynamic therapy (PDT) of cancer cells. PDT is known as an effective, simple treatment method without the need for surgery. Investigations on the particle structure revealed that the nanoparticles were fabricated with a core-shell structure of ~192 nm. The PDT effects of the nanoparticles on HeLa cancer cells were invest

BACKGROUND: Bone marrow-derived mesenchymal stem cells (BMSCs) and bone morphogenetic protein-2 (BMP-2) have been studied for bone repair because they have regenerative potential to differentiate into osteoblasts. The development of injectable and in situ three-dimensional (3D) scaffolds to proliferate and differentiate BMSCs and deliver BMP- 2 is a crucial technology in BMSC-based tissue engineering. METHODS: The proliferation of mouse BMSCs (mBMSCs) in collagen/poly-c-glutamic acid (Col/c-PGA)

The unique properties of graphene quantum dots (GQDs) make them interesting candidate materials for innovative applications. Herein, we report a facile method to synthesize aminofunctionalized graphene quantum dots (AF-GQDs) by a hydrothermal reaction. Graphene oxide (GO) was synthesized by Hummer's method where ultra-small GO sheets were obtained by a prolonged oxidation process followed by sonication using an ultrasonic probe. Subsequently, graphene hydrogel (GH) was also obtained by a hydroth

In the quest of extending isostructural hybridization approach to organic–inorganic nanocomposite-based photocatalytic systems, a unique strategy of replacing the traditional inorganic semiconductors with naturally produced mycosporine-like amino acids (MAA) is proposed. The main motivation of incorporating MAA in symbiotically configured nanocomposites is with regard to MAA green, nontoxic nature, UV absorption and photostability. Our facile one-pot solvothermal method is to facilitate the amal

Gold particles have been widely used in the treatment of prostate cancer due to their unique optical properties, such as their light-heat conversion in response to near-infrared radiation. Due to well-defined synthesis mechanisms and simple manufacturing methods, gold particles have been fabricated in various sizes and shapes. However, the low photothermal transduction efficiency in their present form is a major obstacle to practical and therapeutic uses of these particles. In the current work,

Owing to its precise manipulation in nanoscale, DNA as a genetic code becomes a promising and generic material in lots of nanotechnological outstanding exploitations. The nanoscale assembly of nucleic acids in aqueous solution has showed very remarkable capability that is not achievable from any other material resources. In the meantime, their striking role played by effective intracellular interactions have been identified, making these more attractive for a variety of biological applications.