유희준 교수
Yoo Hee Joon
한양대학교 피부과 · 의학
연구실 소개
유희준 교수의 연구실은 주로 피부질환의 진단 및 병리학적 특성에 중점을 두고 있으며, 특히 희귀 피부질환과 임상적으로 특이한 병변의 분류 및 메커니즘 규명을 핵심 연구 방향으로 삼고 있습니다. 고령자나 면역저하자에서 발생하는 공격성 피부암, 퇴행성 피부병변, 그리고 스테로이드 오남용에 의한 변형된 피부감염 등 다양한 임상 유형의 병리학적 분석을 통해 정확한 진단 기반의 치료 전략을 모색하고 있습니다. 특히 희귀병리학적 병변의 임상·세균학적 특성과 조직형광검사, 유전자 분석을 융합한 종합적 접근이 특징입니다.
연구 현황
연구 성과 추이
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주요 논문
15Tinea incognito (TI) is a dermatophytic infection which has lost its typical clinical appearance because of improper use of steroids or calcineurin inhibitors. The incidence of TI is increasing nowadays. We conducted retrospective review on 283patients with TI from 25 dermatology training hospitals in Korea from 2002–2010to investigate the demographical, clinical, and mycological characteristics of TI,and to determine the associated risk factors. More than half (59.3%) patients were previously t
Pigmented Bowen’s disease is characterized by increased melanin pigment in the epidermis or papillary dermis, in addition to the typical findings of Bowen’s disease. This disorder has been infrequently reported and it represents less than 2% of all cases of Bowen’s disease. Thus far, there has been only 1 case of pigmented Bowen’s disease on the umbilicus in the medical literature, and no such case has been reported in Korea. Pigmented Bowen’s disease develops on sun-exposed areas of the face an
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Myopericytoma (MP) is a benign tumor composed of cells that show apparent differentiation towards putative perivascular myoid cells called myopericytes. It arises most commonly in the dermis or subcutaneous tissue of the extremities in adults. The most common presentation is a well-circumscribed, slow-growing painless firm mass. A 45-year-old woman presented with a 2-year history of a painless, slowly growing 0.9×0.7 cm sized firm mass in the subcutaneous tissue of the posterior side of the righ
Merkel cell carcinoma (MCC) is a rare, aggressive cutaneous malignancy of the elderly and immunocompromised patients. It is occasionally found coexisting with other diseases, such as squamous cell carcinoma, basal cell carcinoma, actinic keratosis, miscellaneous adnexal tumors,and rarely Bowen disease. A 75-year-old woman presented with a 6-month history of an irregularly shaped erythematous patch on the left mandibular angle. Three months later, a 1.5×1.0 cm sized painless and rapidly growing e
Kimura's disease is a rare inflammatory disorder of unknown etiology primarily seen in young Asian males. It is characterized by painless subcutaneous masses, blood and tissue eosinophilia, and markedly elevated serum immunoglobulin E (IgE) levels. Clinically, the subcutaneous nodules occur predominantly in the head and neck. However, we report the case of a five-year-old boy presenting with an asymptomatic solitary brown pigmented nodule on the left buttock diagnosed with Kimura’s disease. Here
Background: Acute pain can severely interfere with the activities of daily living (ADL) of patients with herpes zoster, but until now, little has been published in the Korean medical literature about the impact of herpes zoster on the ADL. Objective: The objective of this study was to identify the nature and severity of the acute pain of herpes zoster patients and its relationship to the patients’ ADL. Methods: 86 patients with herpes zoster and who visited our hospital from August 2009 to June
Onychomycosis is not uncommon among nail diseases. A review of the reports between 1985 and December 2004 found it to be increasing (0.86%) until 1988 among the outpatients in the department of dermatology, but it decreased thereafter to the current average of 0.48% (0.43~0.53%). No difference was found in the occurrence between the genders. It was most frequently seen in patients aged 40~49 (22%) followed by those aged 50~59 (19.6%), 30~39 (19.3%) and 20~29 (13.6%) respectively, although some d
Background: The presence of serum varicella zoster virus (VZV) immunoglobulin M and G (IgM and IgG) aid diagnosis of and confirmation of immunization against varicella and herpes zoster. However, the relationship between serum VZV IgM and IgG and the clinical characteristics of VZV infection remains unclear. Objective: We evaluated quantitative changes in serum VZV IgM and IgG in accordance with the clinical features of varicella, herpes zoster, and disseminated herpes zoster compared with a nor
Poroid hidradenoma is a benign tumor with eccrine differentiation. It is a recently described variant of a group of neoplasms known as poromas. This neoplasm shows architectural characteristics of hidradenoma (tumor cells confined within the dermis in both solid and cystic components) and cytologic characteristics of poroid neoplasm (poroid and cuticular cells). We herein report a case of poroid hidradenoma in a 51-year-old woman who presented with a solitary, bluish, tender nodule on the latera
A digital mucous cyst (DMC) is clinically characterized by a round to oval, translucent, smooth nodule localized to the dorsal aspect of the distal digits near the distal interphalangeal joint. It usually presents as a solitary lesion, and multiple lesions are uncommon. An 88-year-old man presented with herpetiform translucent papules on the right thumb. We first diagnosed the lesion as molluscum contagiosum or herpetic whitlow. Histopathology showed a cystic space containing mucinous material a
Congenital leukemia is a rare condition diagnosed at birth to 6 weeks of life with an estimated incidence of 4.7 per million live births. In a review, about 25∼30% of cases were well documented as leukemia cutis. We report a case of a 3-month-old infant presented with asymptomatic multiple erythematous to bluish patches and nodules, which had developed about two months ago. Biopsy of the cutaneous lesions revealed immature cells which are overall monotonous with large kidney shaped nucleus, prom
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