정영철 교수
Young‐Chul Jung
연세대학교 정신과 · 의학
연구실 소개
정영철 교수의 연구실은 정신질환, 특히 식이장애, 인터넷게임장애, 알코올 의존성 등에서 나타나는 인지조절 및 정서조절 기전에 초점을 맞추고 있습니다. 뇌의 중추적 기능인 전두엽 피질과 배측전두부피질(dACC)의 기능적 연결성과 회색질량 변화를 분석함으로써, 행동조절과 감정조절의 신경기반 메커니즘을 규명하고자 합니다. 특히 자율신경계 반응, 뇌 영상 데이터, 행동 측정을 융합한 다차원적 접근을 통해 정신질환의 발달 및 유지 메커니즘을 밝히는 데 기여하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15Cortical areas supporting cognitive control and salience demonstrate different neural responses to visual food cues in patients with eating disorders. This top-down cognitive control, which interacts with bottom-up appetitive responses, is tightly integrated not only in task conditions but also in the resting-state. The dorsal anterior cingulate cortex (dACC) is a key node of a large-scale network that is involved in self-referential processing and cognitive control. We investigated resting-stat
Reduced executive control is one of the central components of model on the development and maintenance of Internet gaming disorder (IGD). Among the various executive control problems, high impulsivity has consistently been associated with IGD. We performed voxel-based morphometric analysis with diffeomorphic anatomical registration by using an exponentiated Lie algebra algorithm (DARTEL) to investigate the relationship of gray matter abnormalities to impulsivity in IGD. Thirty-one young male adu
Increased reports of impulsivity and aggression in male adolescents with Internet gaming might reflect their dysfunction in emotion regulation, particularly in suppression of negative emotions, which should affect the various stages of Internet gaming disorder. This study tested the hypothesis that adolescents with Internet gaming disorder would be more disturbed by the emotional interference and demonstrate compromised dorsal anterior cingulate cortex (dACC) activation during a Stroop Match-to-
Alcohol dependence is a chronic disorder that results from a variety of genetic, psychosocial, and environmental factors. Relapse prevention for alcohol dependence has traditionally involved psychosocial and psychotherapeutic interventions. Pharmacotherapy, however, in conjunction with behavioral therapy, is generating interest as another modality to prevent relapse and enhance abstinence. Naltrexone and acamprosate are at the forefront of the currently available pharmacological options. Naltrex
Internet gaming disorder (IGD) is characterized by a loss of control over gaming and a decline in psychosocial functioning derived from excessive gameplay. We hypothesized that individuals with IGD would show different autonomic nervous system (ANS) responses to the games than those without IGD. In this study, heart rate variability (HRV) was assessed in 21 young males with IGD and 27 healthy controls while playing their favorite Internet game. The subjects could examine the game logs to identif
OBJECTIVE: Although suicide is a major cause of mortality for individuals with eating disorders (EDs), researches about potential factors predicting suicide attempts in ED are insufficient. We sought to identify factors associated with suicide attempts in ED. METHOD: A total of 899 patients with ED were assessed via structured interviews. To compare demographic and clinical characteristics of those who had attempted suicide with those who had not, we used chi-square tests and independent t tests
Internet gaming disorder (IGD) is a behavioral addiction involving excessive online game use despite negative psychosocial consequences. Unrestricted online gaming may lead to changes in striatal activity and the relationship between the striatum and other cortical regions. This study investigated structural and functional abnormalities involving the striatum through longitudinal follow-up magnetic resonance imaging (MRI) assessments. Eighteen young males with IGD (mean age: 23.8 ± 2.0 years) an
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