박영선 교수
Youngseon Park
한양대학교 수학과 · 의학
연구실 소개
박영선 교수의 연구실은 주로 청소년기 체류 중인 스마트폰 중독 및 정서적·사회적 특성, 고령 산모의 산전·산후 합병증 위험 요인 분석, 그리고 생물학적 활성 펩타이드의 합성 및 기능성 구조 설계에 초점을 맞춘 연구를 수행하고 있습니다. 특히 스마트폰 사용의 심리사회적 영향과 고령 산모의 건강 위험 요인을 분석함으로써 예방적 의학적 접근을 모색하고 있으며, 자연물에서 유래한 고유한 구조적 펩타이드의 효능 기반 합성 기법 개발도 함께 진행하고 있습니다. 이는 임상적 응용과 신약 개발에 기여할 잠재력을 지닌 분야입니다.
연구 현황
연구 성과 추이
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주요 논문
15This study investigated firstly the cellular phone addiction tendency according to the classification of addiction, dependency, non-addiction and predicting factors of cellular phone use and secondly the psycho-social characteristics of cellular phone use by adolescents?. Participants were 368 students of academic and occupational high schools in Seoul. A prediction model of cellular phone addiction tendency was developed and showed that there were significant effects of cellular phone use-time,
Macrocyclization of peptides is often employed to generate novel structures and biological activities in the biosynthesis of natural products and drug discovery. The enzymatic cross-linking of two side chains in a peptide via an ester or amide has a high potential for making topologically diverse cyclic peptides but is found with only a single consensus sequence in the microviridin class of natural products. Here, we report that a peptide with a new sequence pattern can be enzymatically cross-li
PURPOSE: )-induced thrombosis model is widely used for thrombosis research. However, it lacks standardization with uncertainty in the exact mechanism of thrombosis. This study aimed to characterize thrombus formation in a mouse model. MATERIALS AND METHODS: -induced thrombosis model. We also investigated thrombus histopathology using immunohistochemistry and electron microscopy. RESULTS: treatment area. Transmission electron microscopy showed that RBCs attached to and were surrounded by aggregat
Purpose: The purpose of the study was to examine the predictive relationships between predictors [(difficulty on daily activities due to arthritis, falls, and pain, grip strength, and activities of daily living (ADLs)], and perceived health in community-living older adults in Korea. Method: A descriptive, cross‐sectional survey design was used. Data were obtained from Korean Longitudinal Study of Ageing conducted in 2006. A stratified sample was selected of 5,545 older adults who were over 60 ye
=목적: 35세 또는 40세 이상의 고령 산모에서 연령 및 연령과 관련된 산전 및 산후 합병증의 위험정도를 알아보고자 하였다.연구 방법: 1996년 이후 국내에서 발표된 35세 또는 40세 이상의 고령 산모에 대한 7편의 연구문헌에 대해 메타 분석을 실시하였다.결과: 35세 또는 40세 이상의 고령 산모에 있어서 출산 후 산모 및 신생아 상태는 전반적으로 양호하였다. 그러나, 연구군에서 대조군에 비해 임신 중에 임신 합병증 (조기분만, 태위, 임신성 고혈압, 임신성 당뇨병, 전치 태반, 조기 양막파수)과 자궁 근종, 출산 후 저체중아에 있어서 통계적으로 의의있게 높은 빈도를 보였다.
In this work, we develop novel disk characterization suite, DIG (disk geometry analyzer), which allows us to rapidly extract and to characterize the key performance metric of modern hard disk drive. Development of this tool is accompanied by thorough examination of four off-the-shelf hard disk drives. DIG consists of three key ingredients: O(1) track boundary detection algorithm,O (log n) zone boundary detection algorithm, and hybrid sampling based seek time profiling. We particularly focus on a
With moving of the main of industrial structure from primary industry to secondary and tertiary industries, population concentration to large metropolitans is being accelerated. Korean government executes a plan to rearrange industries at undeveloped regions. This industry rearrange plan will change the structure of industry in each region, and therefore, age structure in each region will also be changed. Accordingly, it is needed to expect the age structure of population which is changed with c
1980년대 초반부터 계속적으로 미국의 측정학계에 소개되어 온 규칙장 모형(Rule Space Model: RSM)은 앞으로 학생들의 인지과정을 진단하기 위한 측정이론이다. 그 진단은 후속적으로 교정학습을 위한 직접적인 지침이 될 수 있다. 이에 본 연구에서는 규칙장 모형의 논리에 근거하여 인지과정의 진단을 가능하게 하는 알고리즘을 개발하고, 모의실험을 통해 이를 적용하여 보았다.
Purpose: Interleukin (IL)-17A has been suggested to play a role in the growth and organization of thrombi. We examined whether IL-17A plays a role in the early stages of thrombosis and whether there are sex differences in the effects of IL-17A. Materials and Methods: We performed a blinded, randomized, placebo-controlled study to compare time to thrombotic occlusion and sex differences therein between mice treated with IL-17A and those treated with saline using a ferric chloride-induced model. W
Clot perviousness on computerized tomography (CT) is predictive of response to reperfusion therapy. This study aimed to determine the association of clot perviousness with ultrastructural features of clot in stroke patients undergoing endovascular thrombectomy. We quantitatively analyzed the ultrastructural components identified using scanning electron microscopy. The clot components were determined in the inner portions of the clots. Clot perviousness was assessed as thrombus attenuation increa
This study analyzed the design elements and fashion images of women's knitwear in collections of Paris, Milan, London and New York between 2003 and 2008, and examined knitwear trends in an effort to verify whether knitwear trends are repeated in certain cycles, whether they show complicated patterns in cycles and yet occur in quasi cycles, or whether they occur non-periodically in complicated forms of chaotic cycles. Trend cycle analysis results are deemed to identify the time series attribute o
In this work, we develop a novel audio and video (A/V) disk which is not only stronger for fragmentation but also getting higher bandwidth for multimedia home appliances. For our work, multimedia workload characteristics and disk overheads in multimedia home appliance are analyzed and then the concept of extent is redefined. If track size is only multiple size of extents, every I/O operation do not have track switch overhead. We suggest three ways of implementing our model in a real disk drive a
The purpose of this study was to investigate the feasibility of different fetal heart rate (FHR)ranges in the nonstress test (NST) and to better understand the meaning of mild bradycardia and/or tachycardia without non-reassuring patterns. We employed the heredity to show that mild bradycardia (100-119 beats per minute, bpm) and mild tachycardia (161-180 bpm) regressed to the normal FHR range (120-160 bpm). We used linear regression to analyze FHR data from FHR tracings recorded 10 min before (N
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