임유진 교수
Yujin Lim
경희대학교 방사선종양학과 · 의학
연구실 소개
임유진 교수의 연구실은 종양의 방사선 치료 및 치료 반응 예측에 초점을 맞춘 임상 연구를 중심으로 전개되고 있습니다. 특히 초기 인두암, 직장암, 유방암 등에서 방사선 치료의 장기적 결과와 생존 예후를 분석하며, 병변의 분자적 특성과 치료 반응 간의 연관성을 규명하고자 합니다. 또한, 항암 효과를 유도하는 외재성 단백질(예:EGF)의 방사선 감수성 유도 기전에 대한 동물 모델 연구를 통해 치료 전략의 개선을 도모하고 있습니다.
연구 현황
연구 성과 추이
표시된 성과는 수집된 데이터 기준으로 산출되며, 일부 차이가 있을 수 있습니다.
주요 논문
15PURPOSE: This study evaluates the long-term results of definitive radiotherapy (RT) for early glottic cancer. Clinical and treatment factors related to local control and patterns of failure are analyzed. MATERIALS AND METHODS: We retrospectively reviewed 222 patients with T1-2N0 squamous cell carcinoma of the glottic larynx treated with definitive RT from 1981 to 2010. None of the patients received elective nodal RT or combined chemotherapy. The median total RT dose was 66 Gy. The daily fraction
Five domestic kiwifruit varieties, Bidan (BD),Chiak (CA), Haegeum (HG), Haehyang (HH), and Mansoo(MS), in Korea and two imported varieties, Hayward (HW)and Hort16A (HT), from New Zealand were evaluated mainactive component groups in the fruit extracts involved inantioxidant and anti-dementia activities. HW, HT, and HHexhibited higher soluble solid content. BD, HG, and HHcontained high total phenolics (TP), whereas two importedkiwifruits and green kiwifruits (MS and CA) had low TPcontent. BD show
BACKGROUND: Despite the widespread use of neoadjuvant chemoradiotherapy, there is no prognostic surrogate marker established in locally advanced rectal cancer. OBJECTIVE: This study evaluated the role of neoadjuvant rectal score as a prognostic factor to stratify individual-level risks of survival and tumor recurrence. DESIGN: This is a retrospective study. SETTINGS: This study was conducted at the Seoul National University Hospital. PATIENTS: A total of 397 patients who underwent chemoradiother
This study evaluated the prognostic impact of ACT in patients who achieved a pathological complete response (pCR). Articles published from January 1990 to September 2018 were searched in EMBASE, PubMed, Ovid, Web of Science, and Cochrane Library. Hazard ratios (HRs) and 95% confidence intervals (CIs) of overall survival (OS) were extracted. Thirteen observational studies were included. There were four National Cancer Database studies with overlapping study periods, thus individual pooled analyse
PURPOSE: This study aimed to identify predictors for distant metastatic behavior and build a related prognostic nomogram in breast cancer. MATERIALS AND METHODS: A total of 1,181 patients with non-metastatic breast cancer between 2003 and 2011 were analyzed. To predict the probability of distant metastasis, a nomogram was constructed based on prognostic factors identified using a Cox proportional hazards model. RESULTS: The 7-year overall survival and 5-year post-progression survival of locoregi
PURPOSE: The purpose of this study was to evaluate whether an exogenous epidermal growth factor (EGF) could induce anti-tumor and radiosensitizing effects in vivo. MATERIALS AND METHODS: BALB/c-nu mice that were inoculated with A431 (human squamous cell carcinoma) cells in the right hind legs were divided into five groups: I (no treatment), II (EGF for 6 days), III (EGF for 20 days), IV (radiotherapy [RT]), and V (RT plus concomitant EGF). EGF was administered intraperitoneally (5 mg/kg) once a
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