김윤정 교수

Quorum sensing has been implicated as an important global regulatory system controlling the expression of numerous virulence factors in bacterial pathogens. SmcR, a homologue of Vibrio harveyi LuxR, has been proposed as a quorum-sensing master regulator of Vibrio vulnificus, an opportunistic human pathogen. Previous studies demonstrated that SmcR is essential for the survival and pathogenesis of V. vulnificus, indicating that inhibiting SmcR is an attractive approach to combat infections by the

BACKGROUND: Asthma is a common respiratory disease that is characterized by bronchial hyperresponsiveness and airway obstruction due to chronic airway inflammation. Atopic asthma is a typical IgE-mediated disease in which the enhanced production of IgE is driven by the activation of Th2 cells, which release a distinct pattern of cytokines, including interleukin 4 (IL4) and IL3, in response to specific antigen presentation. To evaluate the methylation status of the whole genomes of bronchial muco

This study investigated growth and ginsenosides content of ginseng sprouts under various light spectra. One-year-old ginseng seedlings were cultivated under various light treatments including: monochromatic (red (R), green (G), and blue (B)), various RB and RGB combinations, white (fluorescent lamps (FL) and natural white (NW)), and supplemental far red (FR). R and high R ratio increased growth characteristics of ginseng sprouts (excepted for root dry weight). The replacement of G for B in RGB g

A readily synthesizable fluorescent probe DMAT-π-CAP was evaluated for sensitive and selective detection of human serum albumin (HSA). DMAT-π-CAP showed selective turn-on fluorescence at 730 nm in the presence of HSA with more than 720-fold enhancement in emission intensity ([DMAT-π-CAP] = 10 μM), and rapid detection of HSA was accomplished in 3 s. The fluorescence intensity of DMAT-π-CAP was shown to increase in HSA concentration-dependent manner (Kd = 15.4 ± 3.3 μM), and the limit of detection

A new D-glucose-6-phosphate phosphohydrolase (G6Pase) inhibitor, CJ-21,164 (1) was isolated from the fermentation broth of the fungus Chloridium sp. CL48903. The structure was elucidated to be a novel tetramer of the salicylic acid derivatives by spectroscopic analyses. Compound I inhibited G6Pase in rat liver microsomes with an IC50 of 1.6 microM. Glucose output from hepatocytes isolated from rat liver was inhibited when I was present in the incubation medium, consistent with the role of I as a

Privacy-aware Role-based Access Control (P-RBAC) model is one of Role-Based Access Control (RBAC) model extensions that has been proposed to help the enforcement of privacy policies. Despite the enhanced privacy protection mechanism by P-RBAC, its pair-wise policy conflict detection algorithm has been pointed out as one of its limitations because conflicts within more than two policies are not detected. In this paper, we review and extend P-RBAC's existing conflict detection algorithm so that it

Currently, white light-emitting diode (LED)-based light sources are widely used in vertical farms to improve energy efficient and price competitiveness, and white LED with various light spectra have been produced with the development of phosphor technology. In this study, we discussed the radiation effects of white LED with three different light spectra on the growth and the content of saponin and ginsenosides in ginseng sprouts grown in a vertical farm, specifically assessing the ratios of red,

During the last decade in Korea, non-profit organizations (NPO) have shown incredible growth in both their number and size due to the development of civil society and government-subsidizing policies. Most registered NPOs are subsidized by the government but their learning capacities and financial performance in meeting new social needs in an innovative manner is somewhat limited and even less sustainable. In this article, the authors assume that the learning organization characteristics of NPOs

嫁母･出母는 아버지와의 의리가 끊어진 어머니라는 점에서 은혜와 의리가 상충되는 대상이었고 그만큼 예의 실천을 둘러싸고 많은 논의들이 진행되었다. 성종대 再嫁女 자손의 관직 진출이 규제되면서 양반층에게 여성의 재가는 매우 부정적으로 받아들여졌다. 출모 논의는 왕실의 廢妃를 중심으로 이루어졌는데, 폐비 신씨를 통해 죄 없이 쫓겨나는 출모에 대한 인식이 나타나고 있었다. 조선전기 양반 여성의 改嫁가 금지되고 이혼이 억제되는 상황에서 가모･출모에 대한 논의는 제한적으로 이루어지고 있었다. 17세기 이후 병자호란으로 인한 被擄婦女를 失節･改嫁한 것으로 간주하면서, 그녀들과의 이혼이나 그 자손들의 관직 진출과 관련하여 여러 논의들이 이루어졌다. 양반층에서는 자체적으로 피로부녀를 出妻함으로써, 특권 집단의 도덕과 의리를 재확인하고 자신들의 신분적 지위를 유지하고자 하였다. 따라서 수많은 피로부녀들은 실절로 인해 남편과 의리가 끊어진 가모나 출모로 간주되었다. 또한 전쟁 이후 조선 사회 내부에서는

Lignans are phytoestrogens found in various forms such as glycosides, ester-linked oligomers, and aglycones in a variety of foods, including soy products, legumes, grains, nuts, vegetables, and fruits. This study aimed to optimize the extraction of lignans from cereal grains using response surface methodology (RSM). Lignans, including secoisolariciresinol (Seco), matairesinol (Mat), pinoresinol (Pin), lariciresinol (Lar), and syringaresinol (Syr), were quantified using high-performance liquid ch

Fingerprint encryption in embedded environments should satisfy both lightweightedness and secureness. Normally, the encryption scheme divides the 8‐bit pixel images into bit planes and then performs full encryption for one bit plane, e.g. least significant bit plane, and simple operations for the remaining bit planes. Thus, the scheme performs better compared with the 8‐bit full encryption, while the security is decreased since only one bit plane is fully encrypted. An innovative fingerprint enc

이 논문은 주자학적 의례의 핵심인 가묘제를 중심으로 여성과 관련된 제사의례의 변화를 고찰하였다. 종법적인 가묘제의 실천은 양측적 친족질서에 기반한 여성의 사회적 지위와 충돌을 일으켰고 이러한 갈등을 해소하기 위해 다양한 예학적 논의가 이루어졌다. 유교화 이전 조선사회에서 딸과 총부에 의한 제사는 관행적으로 이루어졌다. 그러나 여성은 가묘를 세우고 신주에 방제할 수 없다는 점에서 이러한 관행은 예학적인 비판을 받았다. 이에 입후를 통한 제사와 가묘의 승계가 중시되면서 여성의 봉사권은 입후를 기다리는 동안의 임시적인 것으로 제한되었다. 가묘제에서 여성의 제향자로서의 위치는 의제적 관계에 의해 결정되었다. 아버지 생존 시에는 가묘의 주인인 아버지가 망처의 상제를 담당하였다. 무후로 사망한 전모와 계모도 아버지의 적처로 인정되어 가묘의 주인인 승중의자에게 어머니로서 제사를 받게 되었다. 혼인한 여성은 남편과 함께 부계의 가묘에 제향되어야 했으므로 본종의 동성부녀에 대한 제사권은 제한되었다.

Relationships between mothers-in-law and daughters-in-law in Korea have been identified as relationships of conflict. This kind of conflict was exacerbated by sijibsali (living in the husband’s house) of daughters-in-law in the system of clan rules (宗法) in the later Joseon dynasty period. Then what was it like in the earlier Joseon dynasty period, which is known for such strong clan rules, were these relations not settled firmly? The scholar-officials (士大夫) of the earlier Joseon dynasty tried to