김윤중 교수

Accumulation of alpha-synuclein (αSyn) protein in neurons is a renowned pathological hallmark of Parkinson’s disease (PD). In addition, accumulating evidence indicates that activated inflammatory responses are involved in the pathogenesis of PD. Thus, achieving a better understanding of the interaction between inflammation and synucleinopathy in relation to the PD process will facilitate the development of promising disease-modifying therapies. In this review, the evidence of inflammation in PD

External ear reconstruction using 3D printed PCL implant showed durable, safe results reflected by excellent volume restoration and patient satisfaction at 1 year postoperatively. Further clinical follow-up with more cases and refinement of scaffold with advancing bioprinting technique is anticipated. The study's plan and results have been registered with the Clinical Research Information Service (CRIS No. 3-2019-0306) and the Ministry of Food and Drug Safety (MFDS No. 1182).

The Montreal Cognitive Assessment (MoCA) is recommended for assessing general cognition in Parkinson’s disease (PD). Several cutoffs of MoCA scores for diagnosing PD with cognitive impairment (PD-CI) have been proposed, with varying sensitivity and specificity. This study investigated the utility of machine learning algorithms using MoCA cognitive domain scores for improving diagnostic performance for PD-CI.

화본과(Gramineae family)의 Zoysia속(Zoysia genus)에 속하는 한국잔디류는 동북아시아와 필리핀, 태국을 비롯한동남아시아의 열대지역부터 온대지역에 걸쳐 비교적 폭넓게 분포하는 대표적인 잔디종의 하나이다. 세계적으로 방대한 잔디분야의 ‘The Turfgrass Information Center’의database에 zoysia와 연관된 정보는 전문학술지 논문 638편과 학위논문 및 전문보고서 1,307편을 포함하여 총 5,340건으로 조사 되었다. Zoysiagrass에 관한 연구는 골프코스와 lawn care 관련산업에서의 이용과 그에 따르는 잡초,병충해 등 방제에 따르는 농약에 관한 연구와 종자에 관한 database가 주를 이루고 있다. 본 연구는 한국잔디류에대한 세계적 연구 추세와 지금까지 우리나라에서 연구된한국잔디에 관한 연구내용을 정리·분석 하였다. 통계적으로 우리나라의 주요 학술지에 발표된 한국잔디에 관한논문은 274편이었는데, 식물학적 연구가 10

Purpose: Hereditary parkinsonism genes consist of causative genes of familial Parkinson’s disease (PD) with a locus symbol prefix(PARK genes) and hereditary atypical parkinsonian disorders that present atypical features and limited responsiveness to levodopa(non-PARK genes). Although studies have shown that hereditary parkinsonism genes are related to idiopathic PD at the phenotyp ic, gene expression, and genomic levels, no study has systematically investigated connectivity among the proteins en

BACKGROUND: Auricle reconstruction is among the most challenging procedures in plastic and reconstructive surgery, and the choice of framework material is a critical decision for both surgeons and patients. This meta-analysis compared the outcomes of autologous auricle reconstruction using costal cartilage with those of alloplastic reconstruction using porous polyethylene implants. METHODS: A literature review was conducted using the PubMed and Embase databases to retrieve articles published bet

This study was conducted to investigate the effect of cattle manure application on productivity, feed value, and stock carrying capacity of forage crops in upland and paddy fields at Gang-Wondo area. In the result, dry matter yield of sorghum x sudangrass hybrids obtained was 15.12 ton/ha at the level of 150kg N/ha of composted cattle manure. Significantly highest values of crude protein and total digestible nutrients (TDN) yields obtained were 0.59 and 5.35 ton/ha at the level of 150kg N/ha of

BACKGROUND: This study analyzed the demographic characteristics of patients with facial palsy who were treated using either dynamic or static procedures. This study aimed to compare the frequency of procedure implementation and age distribution between the two groups. METHODS: This study retrospectively analyzed the medical records of patients treated for facial palsy at a single institution from 2014 to 2022. Among cases included in our study, dynamic procedures involved cross-facial nerve graf

Background Many people with a longer second toe or lesser toes experience symptoms such as corns, hammertoe, and numerous others, especially when wearing open-toe shoes. Proximal interphalangeal joint arthrodesis using intraosseous loop wiring performed through a hidden side incision is a useful method to shorten the lesser toes aesthetically.Methods Aesthetic toe-shortening procedures were performed in 30 patients. All patients were evaluated by a physical examination and X-rays, and they under

유전자원으로서의 화본과(Gramineae) 관상용 그래스 식물의 번식을 위한 대량생산체계 확립 및 향후 농가소득 작물로의 개발을 목표로 3가지 화본과 관상용 그래스 (ornamental grass)의 종자 발아촉진과 플러그 묘 생산에 대한 연구를 수행하였다. 종자처리에 의한 새(Arundinella hirta var. ciliate Kodiz)의 최종 발아율은 NaOCl 4% 농도 로 60분 처리구가 52.6%로 나타났으며, NaOH 4% 농도로 30분 처리구가 49.4%로 가장 높았다. Switchgrass(Panicum virgatum)는 NaOCl 4% 농도로 10분 처리구가 20.3%의 발아율을 보였고, NaOH 2% 농도로 60분 처리구가 22.4%로 가장 높았다. 수크령(Pennisetum alpecuroides)은 NaOCl 4% 농도로 60% 처리구가 98.4%의 발아율을 보였고, NaOH는 4% 농도로 30분 처리구가 98.5%로 가장 높았다. 플러그 묘 생산 분석결

For women with extremely ptotic breasts, achieving optimal aesthetic outcomes with implant-based breast reconstruction following nipple-sparing mastectomy presents significant challenges. Traditional mastopexy designs may be considered; however, they often lead to nipple-areola complex necrosis due to inadequate blood supply. We propose a novel approach to breast reconstruction that involves skin de-epithelialization to minimize excess mastectomy skin flap, combined with simultaneous contralater

This experiments was conducted to investigate the influence on organic rice cultivation by continuous use of cow manure in the central region of Korea and investigated productivity of organic rice and feed value, stock carrying capacity of organic rice straw. In the results, application of chemical fertilizer showed higher one of 1st and 2nd year in fresh matter yield (15.77, 30.30ton/ha), dry matter yield (9.90, 13.89 ton/ha), dry matter yield of rice straw (4.88, 7.15ton/ha), dry matter weight

Patients with preserved posterior cortical perfusion were younger than those in the other PD groups. Compared with the other groups, the parieto-temporo-occipital hypoperfusion group tended to have lower Cross-Cultural Smell Identification Test scores, a higher prevalence of rapid eye movement sleep behavior disorder, higher Unified PD Rating Scale motor scores, and more severe reductions in striatal dopamine transporter availability. The risk of dementia conversion was lower in patients with pr