김연희 교수

BACKGROUND AND PURPOSE: Although there is some early evidence showing the value of repetitive transcranial magnetic stimulation (rTMS) in stroke rehabilitation, the therapeutic effect of high-frequency rTMS, along with the physiology of rTMS-induced corticomotor excitability supporting motor learning in stroke, has not been established. This study investigated high-frequency rTMS-induced cortical excitability and the associated motor skill acquisition in chronic stroke patients. METHODS: Fifteen

The time-dependent effect of transcranial direct current stimulation (tDCS) on working memory was investigated by applying anodal stimulation over the left prefrontal cortex. This single-blind, sham-controlled crossover study recruited 15 healthy participants. A three-back verbal working-memory task was performed before, during, and 30 min after 1 mA anodal or sham tDCS. Anodal tDCS, compared with sham stimulation, significantly improved working-memory performance. Accuracy of response was signi

Our results demonstrated that anodal transcranial direct current stimulation over the left dorsolateral prefrontal cortex was associated with enhanced working memory performance as indexed by the recognition accuracy in patients after a stroke.

BACKGROUND: This study aimed to delineate the cerebral attentional network in patients with traumatic brain injury (TBI) and assess for adaptations in this network in response to a rehabilitation intervention. METHODS: Seventeen patients with TBI and 15 healthy subjects underwent functional magnetic resonance imaging (fMRI) using a visuospatial attention task. Ten TBI patients who successfully completed attentional training had a follow-up fMRI. RESULTS: In the TBI patients, fMRI analysis showed

We propose an enhanced three-dimensional integral imaging system using a curved lens array. Incorporation of a curved lens array instead of a conventional flat lens array expands the viewing angle remarkably. The flipped images are eliminated effectively by adopting barriers. The principle of the proposed system is explained and the experimental results are also presented.

A wide-viewing-angle integral three-dimensional imaging system made by curving a screen and a lens array is described. A flexible screen and a curved lens array are incorporated into an integral imaging system in place of a conventional flat display panel and a flat lens array. One can effectively eliminate flipped images by adopting barriers. As a result, the implemented system permits the limitation of viewing angle to be overcome and the viewing angle to be expanded remarkably. Using the prop

Hippotherapy positively affects gross motor function and balance in children with CP of various functional levels.

A resolution and viewing-angle enhanced integral imaging system using electrically movable pinhole array is proposed. A pinhole array on liquid crystal is adopted as dynamic pinhole array in integral imaging. The location of the pinhole array is controlled electrically. The pinhole array is expected to be moved fast enough to make an after-image effect, and the corresponding elemental images are displayed synchronously without reducing the 3D viewing aspect of the reconstructed image. With the p

We synthesized stable Au−Cu 2 S core−shell-type hybrid nanocrystals, in which the spherical Au core encapsulates in the disk-type Cu 2 S nanocrystals (avg. size = 7 ± 1 nm), using the simple in situ solvothermal growth of Cu 2 S on Au nanoparticle seeds. Binding energy and band gap measurement provides evidence for the electron withdrawal of the Au core from the Cu 2 S shell. The Au encapsulation enhances the visible-light-driven photocatalytic degradation yield of methylene blue and rhodamine B

Autoreactive T lymphocytes probably cause pancreatic beta-cell death by inducing apoptosis. To visualize apoptotic beta-cells in vivo, we accelerated diabetes of NOD mice with cyclophosphamide (CY) or adoptive transfer. We also studied whether Fas-mediated apoptosis is involved in the development of diabetes by administrating anti-Fas ligand (FasL) Ab and by grafting Fas-deficient neonatal pancreas from NOD-lpr/lpr mice. Apoptotic cells were clearly shown 8 days after CY treatment. Beta-cell apo

This fMRI study was undertaken to test whether the pathophysiological mechanism of mirror movements in hemiparetic stroke patients involves activation of the unaffected motor cortex. We studied 16 control subjects and 51 stroke patients. fMRI was performed at 1.5 T using a finger flexion-extension movement paradigm. The incidence of bilateral primary sensorimotor cortex activation was significantly increased during movements of the affected hand of stroke patients who showed mirror movements. Mo