东京大学、京都大学、大阪大学等日本QS前10名大学的研究室信息。
Professor Chengshuo Xia's research lab specializes in intelligent human-computer interaction and wearable sensing systems, focusing on energy-efficient and user-adaptive solutions for human activity recognition, gesture recognition, and motion learning. The lab develops innovative methods using virtual sensor data, simulated IMU signals, and optimization algorithms to reduce reliance on physical hardware and costly data collection. Key research directions include sensor placement optimization, low-power energy harvesting from body heat, and cross-modal systems that enable personalized motion training using everyday devices.
Professor Masayuki Akashi's research lab specializes in pediatric allergy and immunology, with a primary focus on non-IgE-mediated food allergies, particularly Food Protein-Induced Enterocolitis Syndrome (FPIES). The lab investigates the clinical phenotypes, epidemiology, and immunological mechanisms of FPIES, with a special emphasis on the rising incidence of egg-induced FPIES in Japan. They also explore diagnostic criteria, oral food challenges, and desensitization therapies, contributing to international consensus guidelines and improving patient management.
Professor Yukinobu Toda's research focuses on algebraic geometry and categorically structured invariants in algebraic geometry, particularly on derived categories, stability conditions, and Donaldson–Thomas invariants on Calabi–Yau 3-folds. His work centers on the interplay between birational geometry, wall-crossing phenomena, and autoequivalences in derived categories, especially through the lens of Fourier-Mukai transforms and spherical/non-spherical objects. He has made significant contributions to the DT/PT correspondence, non-commutative Donaldson–Thomas theory, and the categorical study of flops and crepant resolutions.
Professor Shonosuke Sugasawa's research lab specializes in statistical methodology with a focus on robust and model-based inference for complex data structures. The lab develops advanced Bayesian and frequentist methods for small area estimation, high-dimensional data analysis, and clustered or heterogeneous data, emphasizing robustness against model misspecification and outliers. Key research directions include shrinkage estimation, machine learning integration (e.g., gradient boosting) for individualized treatment effects, and information-theoretic criteria for model selection using robust divergences such as density power divergence and γ-divergence. The lab also pioneers novel computational algorithms, such as generalized EM procedures and objective tuning criteria, to enhance the reliability and interpretability of statistical models in real-world applications.
Professor Tomoko Nakanishi's research lab specializes in reproductive biology and genetic engineering, focusing on sperm cell function, acrosome reaction dynamics, and male fertility mechanisms using transgenic mouse models. The lab employs advanced imaging techniques, such as live fluorescent microscopy, to visualize subcellular events in sperm, particularly the acrosome reaction, and investigates the roles of specific proteins like calmegin in sperm migration and fertilization. Additionally, the lab contributes to human health research by studying genetic disorders such as alpha-1 antitrypsin deficiency through population-scale genomics, including polygenic risk scores and phenome-wide association studies. The lab also extends its expertise to environmental health, examining the long-term impacts of radioactive contamination from the Fukushima nuclear accident on ecosystems and agricultural systems.
Professor Masahiro Sato's research lab specializes in theoretical and computational materials science, focusing on charge transport mechanisms in organic and polymer-based semiconductors. The lab investigates quantum phenomena such as Kondo and Fano effects in low-dimensional nanostructures, as well as the dynamics of charge carriers and streamers in dielectric materials like polyethylene and silicone gel. Using multi-scale simulation techniques—combining first-principles calculations, molecular dynamics, and kinetic Monte Carlo methods—the lab aims to predict macroscopic electrical behavior from microscopic electronic and structural properties without relying on empirical models. Their work bridges fundamental physics with practical applications in power electronics and organic electronics.
Professor L. Oláh's research lab specializes in cosmic muon-based imaging and geophysical exploration, focusing on the development of advanced muon detection technologies for non-invasive subsurface imaging. The lab pioneers the application of muography to study the internal structures of active volcanoes, underground cavities, and geological inhomogeneities with high precision. Key research directions include the design of portable, robust muon telescopes using closed cathode chamber (CCC) technology for field applications in extreme environments. The lab also advances muon tomography systems for real-time monitoring of volcanic activity and subsurface density variations.
Professor Junko Kiriya's research lab focuses on public health and health equity, with a strong emphasis on health literacy, reproductive health, women's empowerment, and maternal health outcomes in low- and middle-income countries. The lab investigates social determinants of health, including parental communication on sexual and reproductive health, social support, and socioeconomic factors influencing health behaviors and service utilization. Key research directions include improving adolescent and maternal health through community-based interventions and policy-relevant research.
Professor Atsushi Taruya's research lab specializes in theoretical cosmology, focusing on the nonlinear evolution of large-scale structure in the universe. The lab develops advanced perturbation theories and statistical methods to model matter power spectra, redshift-space distortions, and baryon acoustic oscillations with high precision. Key research directions include renormalized perturbation theory, non-perturbative resummation techniques, and the application of nonextensive statistical mechanics to self-gravitating systems. The lab combines analytical frameworks with $N$-body simulations to achieve robust predictions for cosmological observables at the percent level accuracy.
Professor Joshua Eby's research lab focuses on theoretical particle physics and cosmology, with a central emphasis on axion-like particles and their astrophysical implications. The lab investigates the formation, stability, and dynamics of axion stars—compact, self-gravitating condensates of axions—using effective field theory, relativistic field equations, and nonrelativistic approximations. Key research directions include the role of self-interactions in stabilizing or collapsing axion stars, the decay of axion condensates, and the capture of dark matter by gravitational potentials such as those of stars. The work bridges fundamental particle physics with observational cosmology, aiming to connect quantum field theory with astrophysical phenomena.
Professor Shunsuke Chiba's research lab specializes in the development of innovative transition-metal-catalyzed transformations for the selective synthesis of nitrogen-containing heterocycles and functionalized organic molecules. The lab focuses on mechanistic studies of C–H functionalization, particularly copper-catalyzed oxidative reactions involving organic azides and sp³ C–H bonds, with an emphasis on novel reactivity patterns such as concerted S<sub>N</sub> Ar substitutions and radical-mediated H-atom abstraction. Recent work highlights the use of molecular oxygen as a green oxidant and the incorporation of O₂ into complex molecular frameworks, underscoring a commitment to atom-economical and sustainable methods.
Professor Osamu Toyoshima's research lab specializes in endoscopic diagnosis and the long-term management of *Helicobacter pylori*-related gastritis, with a focus on the Kyoto classification system as a tool for assessing gastric atrophy, intestinal metaplasia, and gastric cancer risk. The lab investigates the impact of *H. pylori* eradication on endoscopic and serological markers, aiming to improve early detection and prognosis of gastric cancer. Key research directions include the longitudinal evaluation of endoscopic changes post-eradication and the use of serum antibody titers as non-invasive indicators of mucosal inflammation and cancer risk. The lab's work bridges clinical endoscopy, biomarker research, and preventive gastroenterology.
Professor Makoto Yamagishi's research lab focuses on the epigenetic and genetic mechanisms underlying hematological malignancies, particularly adult T-cell leukemia-lymphoma (ATL) caused by HTLV-1 infection. The lab investigates clonal evolution, epigenomic reprogramming—especially EZH2/PRC2-mediated H3K27me3 accumulation—and the interplay between somatic mutations, viral integration, and transcriptional dysregulation in cancer progression. Using integrated multi-omics approaches, including deep sequencing, single-cell RNA-seq, and RISC-capture assays, the lab aims to decode the molecular basis of cellular identity loss and therapeutic resistance in ATL and other lymphoid malignancies.
Professor Daniel Janowski's research lab specializes in fungal ecology, with a primary focus on the ecology, biogeography, and molecular identification of ectomycorrhizal fungi in forest ecosystems. The lab investigates the complex interactions between soil fungi and their plant hosts, particularly in the context of forest biodiversity, conservation, and ecosystem functioning. Using advanced molecular techniques such as next-generation sequencing and GIS-based spatial analysis, the lab aims to map fungal distributions and understand the environmental and biological drivers shaping these patterns. A significant emphasis is placed on understudied regions and host species, including Japanese *Tilia* trees, to uncover novel symbiotic relationships and inform sustainable forest management.
Professor Kensaku Maejima's research lab specializes in plant-microbe interactions, with a focus on phytopathogenic bacteria such as phytoplasmas and their molecular mechanisms of pathogenicity. The lab investigates bacterial effectors—particularly phyllogens and SAP54-like proteins—that manipulate host plant development by targeting key transcription factors like SEPALLATA (SEP) MADS-domain proteins, leading to floral malformations such as phyllody. Using molecular, genetic, and evolutionary approaches, the lab uncovers how these pathogens subvert plant developmental pathways and explores the broader implications for disease control and plant immunity. The work also extends to viral molecular epidemiology, as seen in studies on Plum pox virus diversity and transmission patterns in Japan.
Professor Soichiro Masuda's research lab specializes in spinal surgery and orthopedic surgery, with a focus on improving outcomes in spinal infections, postoperative complications, and osteoporotic vertebral fractures. The lab investigates innovative treatments such as antibiotic-loaded bone cement for spinal surgical site infections and develops predictive models using machine learning to anticipate functional outcomes in elderly patients with osteoporotic fractures. A key emphasis is on early diagnosis and intervention, particularly for complications like postoperative hematoma and drop foot, to optimize patient recovery. The lab integrates clinical data with advanced analytics to enhance personalized treatment strategies in spinal and orthopedic care.
Professor Masanori Sakamoto's research lab specializes in the design and characterization of advanced nanomaterials for sustainable energy conversion, with a strong focus on plasmonics, photocatalysis, and carrier dynamics in semiconductor heterostructures. The lab explores mechanisms of hot-carrier generation and transfer—particularly in plasmonic nanocrystals such as CdS/CuS and CdS/Cu₇S₄—enabling efficient utilization of visible and infrared light for artificial photosynthesis and hydrogen evolution. Using advanced spectroscopic techniques like time-resolved infrared spectroscopy and flash photolysis, the group investigates ultrafast charge transfer processes and interfacial phenomena in complex nanostructures. Their work also extends to functional nanocomposites, including bimetallic nanoparticle-polymer films, for tunable optical and electronic applications.
Professor Hiroki Tanaka's research lab specializes in advanced plasma-based light sources, particularly focusing on extreme ultraviolet (EUV) generation using laser-produced plasmas for next-generation optical lithography. The lab investigates the emission characteristics and conversion efficiency of EUV radiation from CO₂ and Nd:YAG laser-produced plasmas with tin and xenon targets, aiming to optimize source performance for industrial scalability. Additionally, the lab explores biofilm reactor systems for wastewater treatment, specifically analyzing nitrification kinetics under varying environmental conditions. The research spans both high-energy physics applications and environmental engineering, with a strong emphasis on experimental characterization and process optimization.
Professor Yu Uneno's research lab specializes in oncology and supportive care for elderly cancer patients, focusing on improving quality of life through personalized prognosis prediction, management of chemotherapy-related complications, and early detection of rare paraneoplastic syndromes. The lab leverages real-world big data and time-series analysis to develop adaptive clinical prediction models, aiming to optimize treatment strategies in geriatric oncology. Their work also explores the impact of targeted therapies on neurological outcomes in cancer patients with autoimmune paraneoplastic syndromes.
Professor Hirofumi Yamada's research lab specializes in advanced nanoscale imaging and characterization of biological molecules using frequency modulation atomic force microscopy (FM-AFM) in liquid environments. The lab focuses on achieving molecular-level resolution to study the structure and dynamics of membrane proteins, such as bacteriorhodopsin and chaperonins like GroEL. A key research direction involves minimizing instrumental noise—particularly in the optical beam deflection system—to enhance imaging sensitivity and stability. The lab also explores the fundamental limits of AFM resolution and noise control for biological applications.
