东京大学、京都大学、大阪大学等日本QS前10名大学的研究室信息。
Professor Tomoki Hiraoka's research lab specializes in terahertz science and nanophotonics, focusing on the generation, manipulation, and application of terahertz radiation using novel semiconductor devices and nanostructured materials. Key research directions include terahertz frequency combs, ultrafast optical control in 2D materials, and the interaction of structured light—such as vortex beams with orbital angular momentum—with metamaterials and plasmonic systems. The lab develops compact, low-power, and room-temperature-compatible terahertz sources for applications in high-speed communications, molecular spectroscopy, and ultrafast electronics.
Professor Akio Ishii's research lab specializes in computational materials science, focusing on the atomistic and continuum-scale modeling of phase transformations, defect dynamics, and elastic interactions in metallic materials. The lab investigates phenomena such as diffusion in dislocations, hydride precipitation, shape memory effects, and fracture mechanisms in zirconium and iron-based alloys, with an emphasis on linking atomic-scale simulations to macroscopic material behavior. Using advanced simulation techniques—including molecular dynamics, accelerated dynamics, and phase-field modeling—combined with Eshelby’s inclusion theory, the lab develops predictive models for microstructure evolution and mechanical degradation.
Professor Eiichi Tamiya's research lab specializes in the development of advanced label-free optical biosensors for rapid, sensitive, and real-time detection of biomolecules, with a focus on medical diagnostics and environmental monitoring. The lab pioneers innovative platforms based on localized surface plasmon resonance (LSPR) using gold-capped nanoparticle substrates functionalized with biomolecular probes such as peptide nucleic acids (PNAs) and antibodies. Key research directions include the integration of these biosensors with microfluidic systems for point-of-care diagnostics, particularly for viral pathogens and food allergens. The lab emphasizes practical, low-cost, and high-throughput sensing solutions compatible with standard laboratory equipment like UV–Vis spectrophotometers or flatbed scanners.
Professor Yuya Sasaki's research lab specializes in nanoscale materials physics and advanced data analytics, with a focus on the optical and phononic properties of semiconductor nanomaterials such as SiC and Ge nanoparticles. The lab investigates size-dependent phonon behaviors using spectroscopic techniques like Raman scattering and infrared absorption, employing theoretical models such as Mie scattering and Maxwell-Garnett effective medium approximations. In parallel, the lab explores emerging technologies in terahertz photonics and IoT-driven big data systems, including efficient query processing in mobile ad hoc networks and the application of large language models in software engineering.
Professor Mikako Hayashi's research lab specializes in operative dentistry and dental biomaterials, with a strong focus on the clinical performance, longevity, and biocompatibility of dental restorations. Her work centers on evaluating the long-term outcomes of ceramic inlays, composite restorations, and resin cements, particularly in relation to marginal integrity, wear, post-operative sensitivity, and bond strength. The lab also investigates clinical teaching methodologies in dentistry, especially the education of posterior composite restorations in undergraduate dental programs in Japan.
Professor Toshiyuki Yoneda's research lab focuses on the molecular mechanisms underlying cancer metastasis, particularly the bone-seeking behavior of breast cancer cells and the role of the tumor microenvironment in promoting metastatic progression. The lab investigates key biological processes such as tumor cell invasion, osteoclastic bone resorption, and the influence of acidic extracellular microenvironments driven by V-ATPase activity. Using in vivo models and in vitro systems, the lab explores therapeutic strategies targeting metastasis, including bisphosphonates and MMP inhibitors, with an emphasis on optimizing combination therapies for bone and visceral metastases. Their work bridges basic cancer biology with translational applications to improve treatment outcomes.
Professor Kouki Wakita's research lab specializes in maritime autonomous systems, with a focus on intelligent control and dynamic modeling for autonomous ship navigation, particularly in complex harbor maneuvers such as berthing and unberthing. The lab develops advanced system identification techniques using machine learning—especially neural networks and reinforcement learning—to create accurate, robust, and generalizable ship maneuvering models from limited real-world data. Key research directions include data augmentation for improved model generalization, uncertainty-aware prediction in non-parametric system identification, and optimization of celestial navigation systems for surface ships.
Professor Mitsuru Itoh's research lab specializes in condensed matter physics and bioactive peptide science, focusing on the emergence of ferroelectricity in complex oxide perovskites like SrTiO₃ through isotope engineering, and the investigation of α-cluster states in light nuclei using inelastic α-scattering. The lab also explores the biological functions of protein-derived peptides, particularly antihypertensive activities from porcine muscle proteins. These diverse research directions span from fundamental quantum phenomena in oxides to translational applications in health and nutrition.
Professor Takeshi Kuroda's research lab specializes in computational and atmospheric science, focusing on the dynamics of planetary atmospheres—particularly Mars—using high-resolution general circulation models (GCMs). The lab investigates gravity waves, baroclinic planetary waves, and their roles in atmospheric circulation, weather systems, and cloud formation, especially in relation to seasonal and dust storm impacts. Additionally, the lab explores spin dynamics in wide-bandgap semiconductors, such as GaN, through ultrafast optical measurements, contributing to the understanding of spin relaxation in materials for next-generation optoelectronics. These diverse research directions reflect a strong integration of planetary science and condensed matter physics.
Professor Hiroshi Kunikata's research lab specializes in retinal and anterior segment diseases, with a strong focus on the pathophysiology of glaucoma, diabetic retinopathy, and retinal detachment. The lab investigates molecular and metabolic mechanisms underlying retinal degeneration, including inflammatory cytokines, oxidative stress, and reactive sulfur species in ocular fluids. Using advanced techniques such as metabolomics and clinical imaging, the lab aims to identify non-invasive biomarkers and novel therapeutic targets for early diagnosis and intervention in blinding eye diseases.
Professor Hiroshi Naganuma's research lab specializes in the development and characterization of multiferroic thin films, with a primary focus on bismuth ferrite (BiFeO3) systems. The lab investigates the enhancement of ferroelectric and magnetic properties through elemental doping—particularly cobalt and copper—aiming to achieve room-temperature multiferroicity with low leakage current and high coercivity. Key research directions include optimizing film deposition techniques such as chemical solution deposition, understanding conduction mechanisms in leaky ferroelectrics, and exploring spintronic applications such as spin oscillators and magnetic tunnel junctions. The lab also addresses challenges in achieving low-power, high-frequency spin dynamics for next-generation nanoscale electronic devices.
Professor Anna Suzuki's research lab specializes in fluid flow and mass transport in fractured geological systems, with a focus on integrating advanced imaging, topological data analysis, and machine learning to improve the modeling and prediction of subsurface processes. The lab investigates complex flow mechanisms in fractured media, particularly in geothermal reservoirs and deep geological repositories for nuclear waste, using innovative techniques such as 3D-printed fracture networks and persistent homology to extract physical insights from geometric and topological features. A central theme is the development of physics-informed, data-driven models that bridge the gap between complex geological heterogeneities and predictive simulation. The lab also explores non-Fickian transport behaviors and anomalous diffusion in faulted and fractured rock systems.
Professor Masako Toda's research lab specializes in microbial pathogenesis and host defense mechanisms, with a primary focus on the antibacterial and protective properties of tea components against foodborne and diarrheal pathogens. Her work explores the bioactive compounds in green and black tea—particularly catechins and theaflavins—against antibiotic-resistant bacteria such as methicillin-resistant *Staphylococcus aureus* (MRSA) and *Vibrio cholerae*. The lab also investigates the immunomodulatory effects of advanced glycation end products (AGEs) on allergenic proteins, aiming to understand their impact on immune responses and potential allergenicity. These studies bridge traditional dietary components with modern microbiological and immunological applications.
Professor Masaki Nio's research lab specializes in pediatric surgical oncology and hepatobiliary surgery, with a primary focus on biliary atresia and rare pediatric abdominal tumors. The lab investigates surgical outcomes, optimal timing for Kasai portoenterostomy, and long-term survival in children with biliary atresia, drawing on extensive clinical data from national registries. They also explore minimally invasive surgical techniques, such as thoracoscopic surgery, for pediatric neoplasms. The lab's work emphasizes improving surgical strategies and long-term outcomes in pediatric patients with complex hepatobiliary conditions.
Professor Takuro Kobashi's research lab specializes in paleoclimatology and ice core science, focusing on reconstructing past climate variability using noble gas isotopes—particularly argon and nitrogen—in trapped air bubbles from polar ice cores. The lab develops innovative isotope-based thermometric techniques to derive high-resolution, physically constrained surface temperature reconstructions over the Holocene and the last millennium, with a primary focus on Greenland. Their work bridges climate dynamics, atmospheric circulation, and long-term climate forcings such as solar variability, volcanic eruptions, and greenhouse gas changes.
Professor Shuji Asai's research lab focuses on the cellular and molecular mechanisms underlying tendon repair and regeneration, with a particular emphasis on connective tissue progenitor cells and their potential for tissue engineering and regenerative medicine. The lab investigates the role of these progenitor cells in tendon healing, including their differentiation into tenogenic and chondrogenic lineages, and explores their therapeutic applications in degenerative joint conditions. Additionally, the lab contributes to clinical rheumatology research, examining the impact of disease-modifying antirheumatic drugs—particularly methotrexate and biologics—on disease progression, joint replacement rates, and patient outcomes in rheumatoid arthritis.
Professor Yuji Ando's research lab specializes in wide-bandgap semiconductor devices, with a primary focus on AlGaN/GaN high-electron-mobility transistors (HEMTs) and heterojunction field-effect transistors (HFETs). The lab investigates advanced device structures such as field-plated HEMTs, Al2O3/AlGaN MOS-HEMTs, and GaN-on-thin-sapphire HJFETs to achieve high power density, excellent linearity, and superior thermal and electrical stability. Key research directions include quantum-well engineering, charge control modeling, interface passivation, and post-metallization annealing for enhanced device performance and reliability.
Professor Ana Davila's research lab specializes in advancing machine learning and robotics for medical applications, with a focus on surgical robotics, medical image analysis, and intelligent surgical systems. The lab develops innovative solutions for real-time control, adaptive learning, and human-robot collaboration in minimally invasive surgery, emphasizing robustness under domain shift and limited data. Key research directions include efficient fine-tuning of pre-trained models for surgical imaging, voice-controlled robotic assistants, and inverse kinematics solvers for instrument motion constraints. The lab integrates deep learning, evolutionary optimization, and real-time control to improve surgical precision, safety, and surgeon workflow.
Professor Bisei Ohkawara's research lab focuses on signaling mechanisms underlying embryonic development and neuromuscular synapse formation, with a central emphasis on Wnt signaling pathways—particularly non-canonical Wnt/PCP and Wnt/beta-catenin—during vertebrate gastrulation and neural patterning. The lab investigates the roles of key signaling modulators such as the prorenin receptor (PRR), V-ATPase, and HSPGs in regulating cell polarity and morphogenesis. Additionally, the lab explores the molecular basis of congenital myasthenic syndromes, identifying disease-causing mutations in synaptic receptors like LRP4 and dissecting their impact on neuromuscular junction stability and function. These studies integrate zebrafish and Xenopus models with molecular genetics and biochemical assays to uncover conserved signaling mechanisms in development and disease.
Professor Mitsuru Esaki's research lab specializes in advanced endoscopic therapies for early gastrointestinal cancers, with a focus on optimizing endoscopic submucosal dissection (ESD) techniques for gastric and esophageal neoplasms. The lab investigates technical innovations, such as novel endoscopic knives (e.g., Clutch Cutter) and procedural strategies (e.g., ESD-M, ESD-P), to improve resection efficacy, reduce complications, and lower treatment costs. Research also emphasizes patient-specific treatment selection, particularly in elderly populations, to enhance curative outcomes and quality of life.
