ソウル大学、KAIST、延世大学など韓国QSトップ10大学の研究室情報です。
Professor Hyun Sil Kim's research lab focuses on the molecular mechanisms underlying cancer metabolism, particularly the role of metabolic reprogramming in tumor progression and therapeutic resistance. The lab investigates key regulators such as Snail (SNAI1) in modulating catabolic pathways like fatty acid oxidation and glycolysis, with a strong emphasis on how these processes support cancer cell survival under stress. Additionally, the lab explores the pathophysiology of fibrotic diseases, especially in salivary glands, by examining the TGF-β signaling pathway and its potential as a therapeutic target. The integration of immunology, cancer metabolism, and fibrosis mechanisms defines the lab’s interdisciplinary approach to understanding disease mechanisms and identifying novel therapeutic strategies.
Professor Zhixiong Li's research lab specializes in hydrological modeling and water resources management, with a focus on advanced data-driven techniques for accurate water level and flow forecasting. The lab emphasizes the development and application of machine learning models—particularly improved support vector machines and other intelligent algorithms—for short-term and long-term hydrological predictions. Research directions include model optimization, parameter tuning via cross-validation, and performance evaluation using metrics like RMSE, MAPE, and the index of agreement. The lab's work supports sustainable water resource management, flood control, and reservoir operation in major river basins such as the Yangtze River.
Professor Sung-Han Kim's research lab focuses on infectious disease pathogenesis, particularly viral and bacterial infections such as SARS-CoV-2, MERS-CoV, and *Staphylococcus aureus* bacteremia. The lab employs single-cell genomics and clinical cohort studies to dissect immune responses and identify host factors driving severe disease outcomes. It also develops innovative photothermal antibacterial coatings using functional polymers for biomedical applications. The integration of clinical microbiology, immunology, and materials science defines the lab’s translational research approach.
Professor Jongmin Kim's research lab specializes in synthetic biology and systems biology, focusing on the design and engineering of artificial biochemical circuits inspired by natural regulatory networks. The lab develops in vitro transcriptional systems using minimal enzymatic components to construct programmable genetic circuits, including oscillators and logic gates, with applications in biocomputing and synthetic therapeutics. A key focus is on understanding and replicating fundamental biological principles such as fold-change detection and exact adaptation in synthetic systems, enabling robust and scalable molecular computation. The lab also explores CRISPR-based tools for sequence-specific nucleic acid sensing and genome editing, emphasizing modular, programmable, and sequence-independent control for precision biotechnology.
Professor Seung Soo Yoon's research lab specializes in the design and synthesis of advanced organic semiconductors for optoelectronic applications, with a primary focus on thermally activated delayed fluorescence (TADF) emitters and blue-light-emitting materials for organic light-emitting diodes (OLEDs). The lab explores molecular engineering strategies—such as asymmetric molecular architecture, donor-acceptor engineering, and end-capping with silane or fluorene units—to achieve high-efficiency, stable blue emission. Their work also extends into the development of synthetic receptors and peptide-binding molecules, demonstrating interdisciplinary expertise in molecular recognition and functional materials.
Professor Dae Jin Kim's research lab specializes in computational mechanics and structural engineering, with a focus on advanced numerical methods for fracture mechanics and structural performance evaluation. The lab develops and applies generalized finite element methods (GFEM) to accurately model complex three-dimensional crack problems and global-local interactions in structural systems. Research also extends to structural behavior of steel modular systems, reinforced concrete slabs with openings, and the mechanical performance of connections under various loading conditions. The lab integrates experimental testing with advanced analytical and computational modeling to address real-world engineering challenges.
Professor Jeong-Eun Lee's research lab specializes in astrochemistry and star formation, focusing on the chemical and physical evolution of star-forming cores from pre- to protostellar stages. The lab combines multi-phase modeling of gas dynamics, dust radiative transfer, molecular chemistry, and radiative transfer to interpret submillimeter and infrared observations. Key research directions include molecular line variability, chemical depletion in dense cores, and the role of protostellar feedback in shaping molecular chemistry. The lab also explores advanced materials for oxide semiconductor devices, particularly graphene-embedded oxide TFTs for stable high-temperature operation.
Professor Je-Yeon Yun's research lab specializes in computational and translational neuroscience, focusing on the neural underpinnings of internalizing disorders such as major depressive disorder, obsessive-compulsive disorder, and psychosis. Using advanced neuroimaging techniques—including structural and functional MRI, graph theory, and machine learning—her lab investigates brain network organization, structural covariance, and their relationships with psychopathology, well-being, and behavioral factors. A central theme is identifying neurobiological signatures and potential biomarkers for early detection and personalized intervention in mental health conditions.
Professor Taeho Lim's research lab specializes in the development of advanced nanomaterials for clean energy applications, with a primary focus on fuel cell technologies. The lab investigates ultra-low platinum catalysts and carbon-encapsulated nanostructures to enhance catalytic stability and reduce costs in proton exchange membrane and direct methanol fuel cells. Their work addresses critical challenges such as methanol crossover and catalyst poisoning by designing functional materials that simultaneously promote oxygen reduction while suppressing methanol oxidation. Additionally, the lab explores astrophysical phenomena, including far-ultraviolet emissions in interstellar clouds, linking materials science with astronomical observations.
Professor Seung-Eun Lee's research lab focuses on interdisciplinary studies at the intersection of neuroscience, materials science, and biomedical engineering. The lab investigates the molecular mechanisms underlying neurodegenerative diseases such as Alzheimer’s disease and Niemann-Pick disease type C using advanced 3D brain organoid models, with a particular emphasis on mitochondrial dysfunction, proteinopathies (e.g., Aβ and p-Tau), and lysosomal storage defects. In parallel, the lab develops next-generation spintronic devices, including perpendicular magnetic tunnel junctions (p-MTJs), for high-performance memory and sensing applications, while also exploring scintillator materials for improved medical imaging in brain-dedicated PET systems. These diverse research directions are united by a common goal: advancing fundamental understanding and developing innovative technologies for neurological disease diagnosis and treatment.
Professor Shinhyun Choi's research lab specializes in advanced resistive switching devices, particularly memristors and RRAM (resistive random access memory), with a focus on their applications in neuromorphic computing and artificial intelligence. The lab investigates fundamental resistance switching mechanisms, including oxygen vacancy dynamics and filament formation, using advanced characterization techniques such as noise analysis and in-situ microscopy. Key research directions include improving device reliability and uniformity through novel material engineering—such as amorphous TiO₂-based structures and halide doping—while enabling scalable, high-performance crossbar architectures for non-von Neumann computing systems. The lab also explores online, unsupervised learning implementations using memristor arrays, demonstrating practical applications in principal component analysis and feature extraction.
Professor Dongsup Kim's research lab specializes in computational biology and bioinformatics, focusing on understanding the three-dimensional organization of the genome and its role in gene regulation. The lab develops advanced computational tools and machine learning models to analyze chromatin interactions, topologically associated domains (TADs), and protein-ligand interactions. Key research directions include the integration of multi-omics data, the prediction of binding affinities using graph neural networks, and the construction of coevolutionary residue networks to uncover functional protein residues. The lab also pioneers databases like 3DIV to enable accessible, genome-wide exploration of 3D chromatin architecture.
Professor Hong Joo Lee's research lab specializes in advanced computational methods and materials science with a focus on medical image analysis, deep learning for biomedical applications, and functional micro/nanofabrication. The lab develops innovative AI-driven segmentation and facial landmark detection techniques that integrate geometric priors and uncertainty estimation to enhance accuracy and robustness in complex medical and visual data. Additionally, the lab explores the fabrication of microfluidic devices using ceramic-polymer materials for applications in lab-on-a-chip systems and MEMS, emphasizing thermal and mechanical stability. The research bridges artificial intelligence, biomedical engineering, and advanced materials for next-generation diagnostic and sensing technologies.
Professor Sung Soo Ahn's research lab focuses on autoimmune and systemic inflammatory diseases, with a particular emphasis on understanding disease mechanisms, identifying predictive biomarkers, and improving clinical outcomes in conditions such as adult-onset Still’s disease (AOSD), IgG4-related disease (IgG4-RD), antineutrophil cytoplasmic antibody-associated vasculitis (AAV), and lupus nephritis. The lab integrates clinical immunology with advanced imaging techniques like 18F-FDG PET/CT to assess disease activity and organ involvement, while also investigating the risks of complications such as macrophage activation syndrome (MAS) and hepatitis B virus reactivation in patients receiving targeted biologic therapies. A central theme is the translation of laboratory findings into practical clinical tools for early diagnosis, risk stratification, and personalized treatment strategies.
Professor Dong Hoe Kim's research lab specializes in advanced materials for renewable energy applications, with a primary focus on perovskite-based optoelectronic devices and nanostructured materials for energy conversion and storage. The lab pioneers the development of high-efficiency, stable perovskite solar cells—particularly wide-bandgap and all-perovskite tandem architectures—through innovative defect passivation, anion engineering, and novel film growth techniques. Additionally, the lab explores functional oxide and heterostructured nanomaterials, such as SnO₂-In₂O₃ and TiO₂-CoO₂ systems, for applications in lithium-ion batteries and spintronic devices. Their work emphasizes the correlation between nanostructure control, defect engineering, and device performance.
Professor Hae Sun Jung's research lab specializes in the intersection of artificial intelligence, financial technology, and sustainability, with a strong focus on leveraging natural language processing and machine learning to extract actionable insights from unstructured text data. The lab investigates ESG (Environmental, Social, and Governance) factors in financial markets using advanced NLP models like BERT, RoBERTa, and ALBERT to automate ESG scoring and predict market trends. It also explores cryptocurrency price dynamics by analyzing multi-source textual data from social media (Reddit), news archives (LexisNexis), and academic databases (Web of Science), applying topic modeling and deep learning techniques. A key research direction involves enhancing predictive modeling through sentiment analysis and technical indicators, particularly in volatile financial and crypto markets.
Professor Jiyun Lee's research lab specializes in translational oncology, focusing on targeted therapy and immunotherapy for advanced non-small cell lung cancer (NSCLC) and breast cancer. The lab investigates novel molecular mechanisms of resistance to targeted agents such as EGFR and ALK/ROS1 tyrosine kinase inhibitors, with particular emphasis on overcoming central nervous system metastases and drug resistance. It also explores ethnic differences in treatment response and immune-related adverse events, especially in Asian populations, to optimize personalized therapy. The lab is actively involved in evaluating next-generation targeted therapies like lorlatinib and trastuzumab deruxtecan in biomarker-selected patients.
Professor Sanghee Lee's research lab specializes in developing novel therapeutic strategies for cancer immunotherapy and neurodegenerative disorders by targeting key cellular pathways such as STING signaling, epigenetic regulation (HDACs), and mitochondrial function. The lab focuses on designing small-molecule modulators—particularly STING agonists and ENPP1 inhibitors—to enhance anti-tumor immunity and overcome resistance to immune checkpoint inhibitors. Additionally, the lab explores advanced upconversion nanomaterials for improved photodynamic therapy, emphasizing biocompatibility and efficiency. Their interdisciplinary approach integrates medicinal chemistry, chemical biology, and fluorescence imaging to advance precision therapeutics.
Professor Sung Hoon Choi's research lab specializes in spinal cord disorders, with a primary focus on degenerative cervical myelopathy (DCM) and osteoporotic vertebral compression fractures (OVCF). The lab investigates the pathophysiology, diagnostic imaging, and surgical outcomes of cervical spine diseases, emphasizing patient-specific factors such as cervical disc height and facet joint space in implant selection. Research also addresses the epidemiology and economic burden of OVCF in the Korean population, highlighting trends in treatment utilization and cost. The lab integrates clinical data with radiological and biomechanical analysis to improve surgical decision-making and patient outcomes.
Professor Woonggyu Jung's research lab specializes in developing advanced optical imaging and sensing technologies for biomedical applications. The lab focuses on miniaturized, portable, and endoscopic optical coherence tomography (OCT) systems, as well as novel fiber-optic and MEMS-based probes for high-resolution, real-time tissue diagnostics. Key research directions include point-of-care diagnostics, multiphoton microscopy integration, and noninvasive 3D optical biopsy using endoscopic OCT. The lab also explores sensitive optical sensors based on thermooptic effects in polymer waveguides for biomedical monitoring.
