世界の主要大学の研究室を探索 — 研究分野と主要論文を一目で確認できます。
Hideaki Kakeya教授の研究室は、微生物から産生される天然物質の同定と構造決定を柱とし、特に抗がん、抗炎症、神経栄養作用を示す新規化合物の探索を進めています。主にストレプトマイセスやマイコスイノムなどから新奇構造の代謝産物を発見し、その生物学的活性機構を分子レベルで解明しています。特に、サイトカイン調節やアポトーシス誘導、神経芽細胞腫瘍細胞への神経芽細胞形成促進作用といった、疾患治療に応用可能な機能性天然物の開発が中心です。
石光教授の研究室では、分子の自己集合を利用した機能性ハイドロゲルやナノスケールのスーパーモレキュラー構造を設計・開発しています。特に、生体分子（タンパク質や酵素）に応答する動的で可逆的な材料を基盤とし、ドラッグデリバリー、医療診断、再生医療への応用を目指しています。また、円偏光発光や光誘導反応を示す新規有機分子系材料の創出にも注力しており、光機能性と生体適合性を両立する次世代バイオ材料の開発を推進しています。
UCHIHASHI教授の研究室では、高時間分解能原子間力顕微鏡（HS-AFM）を用いて、膜タンパク質や酵素の動的構造変化をリアルタイムで可視化する研究を行っています。特に、セルロラーゼの結晶性セルロース分解機構やF1-ATPアーゼの回転メカニズム、膜タンパク質のオリゴマー形成状態の直接観察が特色です。これらの研究を通じて、バイオ燃料効率化や人工タンパク質アセンブリの開発に貢献する基盤技術の確立を目指しています。
Yoshifumi Saisho教授の研究室は、膵臓の構造・機能と代謝疾患、特に2型糖尿病の病態解明を主眼としています。特に、膵臓の体積（実質と脂肪組織）の生涯にわたる変化をCTを用いて定量化し、肥満や2型糖尿病が膵臓に与える影響を臨床的・病理的根拠とともにも解明しています。また、β細胞の質量と機能の維持、および糖尿病治療における患者中心の評価（PROs）の重要性についても包括的な研究を展開しています。
Professor Seung Mi Lee's research lab focuses on maternal-fetal medicine and oral health, with a particular emphasis on the clinical implications of biomarkers in pregnancy and the impact of dental appliances on periodontal health. The lab investigates the role of amniotic fluid markers such as Amnisure and fetal fibronectin in predicting preterm birth and perinatal outcomes, while also exploring the association between periodontopathogens and orthodontic treatment. Additionally, the lab examines the potential of functional food ingredients, such as β-glucan from mushrooms, in developing nutritious, health-promoting food alternatives. These interdisciplinary efforts bridge obstetrics, microbiology, and nutritional science to improve maternal and neonatal health outcomes.
Professor Hak-Jin Kim's research lab specializes in precision agriculture and smart farming technologies, focusing on the development of advanced sensing, imaging, and signal processing techniques for real-time monitoring of crop growth and soil conditions. The lab integrates unmanned aerial vehicles (UAVs), RGB-D cameras, ion-selective electrodes (ISEs), and multisensor fusion systems to enable non-destructive, high-resolution assessment of biophysical and nutritional parameters in crops. Key research directions include automated plant phenotyping, hydroponic nutrient monitoring, and robust positioning for agricultural robots, with an emphasis on data-driven models such as convolutional neural networks and artificial neural networks for improved accuracy and efficiency.
Professor Eunjoon Kim's research lab focuses on the molecular mechanisms underlying synaptic organization, with a central emphasis on the roles of scaffolding proteins and cell adhesion molecules in synapse formation, function, and plasticity. The lab investigates how postsynaptic proteins such as PSD-95, Shank3, and stargazin regulate the clustering and trafficking of neurotransmitter receptors, and how trans-synaptic adhesion systems like NGL-3–LAR and PTPsigma–NGL-3 coordinate bidirectional synapse development. Using genetic, biochemical, and imaging approaches in mouse models and neuronal cultures, the lab explores the functional significance of alternative splicing and post-translational modifications in synaptic proteins linked to neurodevelopmental disorders such as autism spectrum disorders.
Professor Ji Eun Oh's research lab focuses on mucosal immunity, particularly the role of B cells and innate immune responses in protecting against viral infections at barrier surfaces such as the respiratory and genital tracts. The lab investigates how commensal microbiota, pattern recognition receptors, and autophagy influence antiviral immunity, with a strong emphasis on tissue-resident immune cells and host-microbe interactions. Additionally, the lab explores the genetic and molecular mechanisms underlying glioblastoma subtypes, linking tumor heterogeneity to clinical outcomes. Their work integrates immunology, virology, and cancer biology to uncover novel therapeutic targets for infectious and malignant diseases.
Professor Dahl-Young Khang's research lab specializes in the mechanics and fabrication of stretchable and flexible nanomaterials, with a focus on integrating high-performance semiconductors like silicon and carbon nanotubes into elastomeric platforms. The lab pioneers innovative approaches in nanoimprint lithography using flexible, low-surface-energy fluoropolymer molds to enable low-pressure, high-resolution patterning of sub-100 nm features without surface treatment. Central to their work is the controlled use of mechanical buckling at micro- and nanoscales to create wavy, strain-tolerant electronic structures, enabling high-performance stretchable electronics. They also apply continuum mechanics theory to quantitatively analyze nanoscale buckling behavior, particularly in single-wall carbon nanotubes, to extract intrinsic material properties such as Young’s modulus.
Professor Won-Young Lee's research lab focuses on advanced materials for energy conversion and biomedical applications, with a strong emphasis on understanding and engineering surface and interfacial phenomena in oxides for solid oxide fuel cells and ion conductors. The lab investigates cation segregation, grain boundary effects, and defect chemistry in perovskite and ceria-based materials to enhance oxygen reduction and ion transport properties. In parallel, the lab explores metabolic disease mechanisms, particularly non-alcoholic fatty liver disease (NAFLD) and insulin resistance, using preclinical models and clinical biomarkers. The integration of advanced characterization techniques—such as STEM-EDS, XPS, and Kelvin probe microscopy—with computational modeling and translational biomedical research defines the lab’s interdisciplinary approach.
Professor Ki-Young Lee's research lab focuses on signal transduction pathways in innate and adaptive immunity, with a particular emphasis on redox regulation, oxidative stress, and the molecular mechanisms underlying inflammatory and immune responses. The lab investigates key signaling hubs such as NF-κB, ASK1, and TLR4, exploring their regulation by redox-sensitive proteins like peroxiredoxin-1 and multifunctional adaptors such as ECSIT. Using advanced biochemical, structural, and cell biological approaches—including NMR spectroscopy and nanodisc systems—the lab uncovers the structural and functional basis of protein interactions in immune activation and disease pathogenesis.
Professor Fakhar ud Din's research lab specializes in advanced drug delivery systems, with a primary focus on nanotechnology-based formulations for targeted cancer therapy. The lab develops innovative nanocarriers such as niosomes, solid lipid nanoparticles (SLNs), and nanogels to enhance drug solubility, bioavailability, and site-specific delivery while minimizing systemic toxicity. Key research directions include thermosensitive and stimuli-responsive nanocarrier systems for rectal and intravenous administration, aiming to improve therapeutic efficacy and reduce side effects in oncology. The lab also explores novel polymeric and surfactant-based systems for effective delivery of both hydrophilic and hydrophobic anticancer agents.
Professor Jae-il Jang's research lab specializes in the nanomechanical characterization of advanced materials, with a focus on understanding the structure-property relationships in nanoscale systems. The lab employs advanced techniques such as nanoindentation and atomic force microscopy to investigate mechanical behavior, phase transformations, and deformation mechanisms in semiconductors like silicon and germanium, as well as in nanowires and single crystals. Their work bridges materials science, solid mechanics, and surface characterization, aiming to provide precise, reliable mechanical property measurements at the nanoscale. The lab also emphasizes the correlation between mechanical responses and underlying atomic-level structures and intermolecular interactions.
Professor Jin-Gyun Kim's research lab specializes in advanced structural dynamics and mechanical reliability, focusing on component mode synthesis methods for efficient and accurate model reduction in finite element analysis. The lab develops innovative techniques to enhance traditional methods like Craig–Bampton and flexibility-based component mode synthesis, with an emphasis on improving accuracy while minimizing computational cost. Research also extends to materials science, particularly the electrochemical behavior and corrosion properties of magnesium-based sacrificial anodes for marine and aerospace applications. The lab integrates computational mechanics with experimental validation to support the design of high-performance engineering systems.
Professor Wook Park's research lab specializes in developing advanced anti-counterfeiting technologies and secure authentication systems using novel nanomaterials and physical unclonable functions (PUFs). The lab focuses on creating highly unique, irreproducible micro- and nanostructures—such as wrinkle-based codes, QR-coded microtaggants, and chaotic phosphorescent patterns—enabling robust product authentication in pharmaceuticals, IoT devices, and high-security labeling. By integrating optical decoding, DNA-based data storage, and self-organized 3D microstructures, the lab pioneers smart, scalable, and tamper-resistant security solutions for real-world applications.
Kondo教授の研究室は、大気中の微小粒子状物質、特に有機 aerosol と黒炭（BC）の化学的・物理的特性とその環境・気候への影響を、地上観測、航空機搭載計測、およびモデルシミュレーションを統合して解明しています。特に、都市部や森林火災由来のエアロゾルの生成機構、酸化度、揮発性、および大気中での変化を高精度な計測技術を用いて定量的に分析しています。研究は、大気質改善と気候変動緩和に向けた科学的根拠の構築を目的としています。
Motoyuki Otsuka教授の研究室は、マイクロルナ酸（miRNA）の機能とその細胞内制御機構に注目し、特に発生・生殖・がん関連の生理的・病理的プロセスにおけるmiRNAの役割を解明しています。特にDicer1というmiRNA処理酵素の機能解析を通じて、卵巣の黄体形成や新生血管形成の制御にmiRNAが関与することを明らかにしてきました。また、ウイルス感染（HCV）におけるmiR122の機能や、小分子化合物によるmiRNA機能制御の可能性についても研究を展開しています。
Nishimasu教授の研究室は、RNAガイドを用いた核酸酵素Cas9の構造機能解明とその応用技術開発を柱としています。特に、PAM配列の制限を克服する新しいCas9変異体の設計や、リアルタイムでのDNA認識・切断メカニズムの可視化に成功しています。高分解能結晶構造解析と高速原子間力顕微鏡を組み合わせた独自のアプローチにより、ゲノム編集のメカニズムを分子レベルで解明しています。
Seijiro Matsubara教授の研究室は、有機合成化学を基盤とし、特に金属触媒を用いた新規反応の開発と、天然物や医薬候材料の効率的合成を主眼としています。Pd/C触媒を用いた水熱的脱カルボキシル化や、ランタニド塩触媒を用いたアミンのコンジュゲート付加反応、およびジメタル化剤や過酸化シリル化剤を用いた酸化・メチレン化反応の開発が特徴です。これらの反応は、反応条件の穏やかさと選択性の高さが特徴で、複雑な天然物の合成に応用可能です。
本研究室は、気候変動緩和に向けたエネルギーシステムの脱炭素化を柱に、水素・アンモニアを含む水素ベースエネルギーキャリアの国際的役割とその技術的・経済的実現可能性を、詳細なエネルギーシステムモデルを用いて分析しています。特に、日本を含む国際的な脱炭素化シナリオ、エネルギー安全保障と気候政策の両立、および2050年カーボンニュートラルの実現に向けた技術・政策の最適な組み合わせを解明しています。
