世界の主要大学の研究室を探索 — 研究分野と主要論文を一目で確認できます。
Professor János Szebeni's research lab focuses on the immunological and physiological mechanisms underlying hypersensitivity reactions triggered by nanomedicines, particularly those involving polyethylene glycol (PEG)-coated nanoparticles and liposomal formulations. The lab investigates complement activation as a central driver of acute, pseudoallergic reactions—termed CARPA (complement activation-related pseudoallergy)—and explores the role of anti-PEG antibodies in accelerating drug clearance and causing severe adverse events. Using large animal models such as pigs, dogs, and rats, the lab develops and validates preclinical models to study and predict cardiopulmonary and systemic side effects of nanotherapeutics.
Professor Hyung-Mun Yun's research lab focuses on neuropharmacology and molecular mechanisms underlying neurological and neuroinflammatory diseases, with a central emphasis on serotonin receptors—particularly the 5-HT6 receptor—as therapeutic targets for Alzheimer’s disease and depression. The lab investigates cell signaling pathways, glial cell modulation, and the role of endogenous antioxidants such as peroxiredoxin 6 in neurodegenerative and autoimmune disorders like multiple sclerosis. Additionally, the lab explores the use of functional biomaterials, including magnetic nanocomposite scaffolds, for tissue engineering and regenerative medicine. Their work bridges molecular neuroscience, neuroimmunology, and translational therapeutics.
小野田健史教授の研究室では、強相関電子系の電子状態を高分解能角度別光電子分光法（ARPES）を用いて精密に解明しています。主に銅酸化物高温超伝導体と鉄pn好物質の超伝導ギャップ構造やペアリングメカニズムの解明を進め、特にペシューガップと超伝導ギャップの二重エネルギースケール、フェルミアークの形成機構、および非摂動的対称性に起因する電子状態の特異性に注目しています。これらの研究を通じて、超伝導の発現機構が電子相関と対称性の複雑な相互作用によって支配されることを明らかにしています。
Ichiro Hisaki教授の研究室では、水素結合を主軸としたポーラスな有機フレームワーク（HOF）の設計と機能制御を柱として、結晶性と可逆性を兼ね備えた新規機能材料の創出を進めています。特に、熱的・化学的安定性を高めつつ、高い比表面積と永久的な多孔性を実現するための分子設計戦略に注力しており、単結晶X線構造解析を活用した精確な構造解明も特色です。また、CO₂吸着や光化学的反応性といった応用指向の性能向上にも取り組んでいます。
佐井博明教授の研究室は、希土類元素を用いた多機能性金属錯体を基盤とする新しい不斉触媒の開発を主眼としています。特に、レアアース金属とアルカリ金属を組み合わせたヘテロビメタリック錯体が、酸・塩基両性の性質を示し、酵素に類似した高効率で高エナンチオ選択的な反応を実現しています。代表的な応用として、ノイトロアルドール反応における高 optical purity の生成が達成されており、有機合成分野における革新的な手法の確立に貢献しています。
Professor Youngbin Yoon's research lab specializes in combustion science and fluid dynamics, with a focus on turbulent non-premixed jet flames, particularly those involving hydrogen and syngas (H₂/CO) fuels. The lab investigates fundamental combustion phenomena such as flame blowout limits, flame stabilization, and NOx emissions under various flow and injection conditions. Key research directions include the effects of orifice internal flow on liquid jet breakup, flame dynamics in supersonic crossflows, and the scaling of NOx emissions based on residence time and fuel composition. The work has strong applications in gas turbine and combustor design, aiming to improve efficiency and reduce emissions.
Professor Kwanjung Yee's research lab specializes in aerospace and aeronautical systems, with a focus on advanced aerodynamic design, flight vehicle performance optimization, and uncertainty quantification in unmanned aerial vehicles and hypersonic vehicles. The lab conducts computational and numerical studies on rotorcraft aerodynamics, multirotor UAV design for mission-specific performance, snow accumulation in high-speed train environments, and wake vortex dynamics. It also pioneers innovative design methodologies for waverider configurations using direct optimization frameworks based on shockwave physics.
Professor Myeong Hee Moon's research lab specializes in advanced analytical methodologies for the separation, characterization, and proteomic analysis of biological nanoparticles and lipid species. The lab focuses on developing and applying innovative hyphenated techniques—such as field-flow fractionation (FlFFF), nanoflow liquid chromatography, ion mobility spectrometry, and tandem mass spectrometry—to study subcellular organelles, extracellular vesicles, and phospholipids with high resolution and sensitivity. Key research directions include the size-based separation of mitochondria and starch granules, the proteomic profiling of extracellular vesicles, and the structural characterization of phospholipids and lysophospholipids in complex biological matrices.
Professor Dong-Sik Kim's research lab specializes in nanomaterials synthesis and characterization, with a focus on carbon-based nanomaterials such as single-walled carbon nanotubes and zinc oxide nanowires. The lab explores advanced fabrication techniques like laser-interference lithography and chemical vapor transport to create highly ordered nanostructures with tailored optical and electronic properties. Additionally, the lab investigates functional hybrid nanomaterials, including gold nanoparticle-decorated carbon nanotubes, for potential applications in biomedicine and sensing. A parallel research direction involves the behavioral and psychological impacts of adolescent risk behaviors, particularly their links to mental health outcomes.
Professor Hyung Joon Yim's research lab focuses on viral hepatitis, particularly chronic hepatitis B (HBV) and its complications such as hepatocellular carcinoma (HCC). The lab investigates the molecular mechanisms of HBV persistence, drug resistance, and host immune responses, with an emphasis on optimizing antiviral therapy and clinical management. It also explores gut-liver axis alterations in acute-on-chronic liver failure and the role of microbiota in liver disease progression. The lab contributes to evidence-based clinical guidelines and translational research to improve outcomes in liver disease.
Professor Klaus Heese's research lab focuses on neuroinflammation and neurotrophin biology in the context of neurodegenerative diseases, particularly Alzheimer’s disease. The lab investigates microglial activation, neurotrophin signaling (especially NGF), and the molecular mechanisms underlying neuronal survival and degeneration. In parallel, the lab explores sustainable biotechnological applications, including the discovery of novel enzymes from marine microorganisms and the green synthesis of silver nanoparticles using seaweed-derived biomolecules. These interdisciplinary efforts bridge neuroscience, molecular immunology, and environmental biotechnology.
Professor Byungmin Kim's research lab specializes in earthquake engineering and geotechnical earthquake engineering, with a focus on site response analysis, soil-structure interaction, and seismic hazard assessment. The lab investigates dynamic soil behavior using downhole array recordings, particularly from long-duration subduction zone earthquakes, and develops advanced methods for estimating site parameters such as VS30 using seismic wave characteristics. A key emphasis is placed on understanding the effects of basin geometry, liquefaction potential, and local site conditions on structural damage and ground motion amplification.
Professor Myong-In Lee's research lab specializes in atmospheric and climate dynamics, with a focus on tropical and mid-latitude weather systems, including the Madden-Julian Oscillation, intraseasonal variability, heat waves, and the diurnal cycle of precipitation. The lab investigates the roles of moisture advection, cloud-radiation interactions, and land-atmosphere feedbacks in shaping regional and global climate patterns, using advanced general circulation models and data assimilation techniques. A key emphasis is placed on improving the simulation of atmospheric processes through high-resolution modeling and satellite soil moisture assimilation. The lab also explores the impacts of climate variability on extreme weather events in East Asia and North America.
Professor Sang Youl Rhee's research lab focuses on metabolic and vascular complications associated with diabetes mellitus, particularly the role of advanced glycation end-products (AGEs) in disease progression. The lab investigates biomarkers such as glutamine and glutamic acid for early detection of diabetic retinopathy, explores the link between diabetes and neurodegenerative conditions like Parkinson’s disease, and examines the impact of environmental factors—such as blood lead levels—on metabolic syndrome. The research integrates clinical epidemiology with molecular mechanisms to identify novel risk factors and early diagnostic indicators in type 2 diabetes and its complications.
Hirabayashi教授の研究室は、神経発達と細胞内シグナル伝達の分子機構に焦点を当てており、特に神経幹細胞の自己複元とニューロンへの分化のバランスを制御するWnt/β-カテニン経路や、細胞小器官間の接触部位（特にエンドプラズミックリトゥーリュームとミトコンドリアの接触）が神経機能に果たす役割を解明しています。また、神経可塑性に不可欠なシナプス後シグナル伝達の基盤としてのカルシウム動態や、高解像度画像解析技術を用いたミトコンドリアの三次元構造解析にも取り組んでいます。
Terauchi教授の研究室は、次世代シーケンシング（NGS）を活用した植物遺伝学・育種ゲノミクスを柱としており、特に稲の病害抵抗性遺伝子の同定や、突然変異マッピング技術の開発を通じて、農業的重要な特性の遺伝的基盤を解明することを目的としています。MutMapやMutMap-Gapといった革新的な遺伝子同定手法の開発により、迅速かつ高効率な品種改良を実現する仕組みを構築しています。また、病原菌と宿主の相互作用メカニズムの解明にも注力し、進化的な「軍拡争争い」の分子的メカニズムを解き明かしています。
Naoto Katakami教授の研究室は、糖尿病に合併する動脈硬化性疾患、特に大動脈障害に注目し、血管内皮機能障害や血管平滑筋細胞の機能異常を解明しています。特に、糖尿病関連血管障害の予防・管理に向けたバイオマーカー（例：esRAGE）や画像診断（頸動脈IMT、baPWV）の有用性を臨床的・疫学的に評価しています。また、SGLT2阻害薬やシロスタゾールなどの治療法の心血管保護効果についても、臨床試験を基盤にした革新的な研究を推進しています。
Inaba教授の研究室は、タンパク質のジスルフィド結合形成と還元のメカニズムに注目し、特に細菌の膜タンパク質DsbBやERp44といったシャペロン・システイン代謝系の構造的・機能的メカニズムを解明しています。特に、ジスルフィド結合の新生や金属イオン（亜鉛）の調節機能が細胞内シグナル伝達に与える影響を、構造生物学的手法と生化学的解析を融合して研究しています。また、インスリンアナログの安定化や酵素の電子移動機構についても、タンパク質工学的・生化学的視点から革新的な知見を提供しています。
Kimura教授の研究室は、エプスタイン・バーウイルス（EBV）関連疾患の病態解明を柱としており、特に慢性活性型EBV感染症（CAEBV）やT/NK細胞リンパ増殖症の発症機構、ウイルス負荷の定量的解析、ならびに予後因子の解明を進めています。リアルタイムPCRを用いたウイルスDNA定量法の確立や、アジア特有のEBV関連疾患の臨床的・分子的特徴の解明が進んでいます。特に、T細胞やナチュラルキラー（NK）細胞に感染したEBVのクローン増殖が疾患の中心的要因であるという仮説を、臨床的・遺伝的アプローチで裏付けている点が特徴です。
Fumina Tanaka教授の研究室は、農産物の乾燥・保存技術に焦点を当てた物性・熱伝達・機能性コーティングの研究を進めています。特に、玄米やイネ科作物の熱的乾燥挙動や、ナノセルロース・キトサンを用いた機能性フィルムの開発を通じて、食品の品質保持と資源効率の向上を目的としています。X線CTを用いた内部構造解析や、精油含有コーティングの抗真菌性評価も実施しており、食品の鮮度保持と持続可能性に貢献する研究が特徴です。
