世界の主要大学の研究室を探索 — 研究分野と主要論文を一目で確認できます。
Professor Baik Lin Seong's research lab focuses on the molecular mechanisms of protein synthesis, particularly the structural and functional specialization of initiator tRNAs in prokaryotes. The lab investigates how specific tRNA features—such as the absence of a Watson-Crick base pair at the acceptor stem and unique anticodon sequences—determine their role in translation initiation versus elongation. A key research direction involves engineering tRNAs and antigens for improved vaccine design, leveraging RNA chaperone functions and nanoparticle self-assembly to enhance solubility, folding, and immunogenicity of recombinant vaccine antigens. The lab also explores structural determinants of tRNA function and their implications for synthetic biology and therapeutic protein production.
Professor Fabian Jintae Froese's research lab focuses on human resource management, international mobility, and entrepreneurial behavior, with a particular emphasis on expatriate experiences, AI adoption in HR, and the unique dynamics of female entrepreneurs in Asia. The lab explores how individual motivations, organizational support, and cultural contexts shape work adjustment, job satisfaction, and career outcomes in global and cross-cultural settings. It also investigates the role of psychological resources such as resilience and organizational climate in enhancing employee well-being and retention. The research integrates theoretical frameworks from organizational behavior, information systems, and cross-cultural psychology to address contemporary challenges in global talent management and innovation.
Professor Nuri Yun's research lab specializes in nanomedicine and cellular therapeutics, with a primary focus on extracellular vesicles (EVs) as natural delivery vehicles for treating cardiovascular and neurodegenerative diseases. The lab investigates the engineering of small extracellular vesicles (sEVs) and exosomes to enhance targeted delivery of therapeutic molecules such as siRNA, miRNA, and proteins, particularly in myocarditis and myocardial infarction. A key direction involves modifying EV surface proteins—such as cardiac-targeting peptides and LAMP2b—to improve tissue specificity and reduce off-target effects. Additionally, the lab explores the role of cell signaling pathways, including Cdk5/Fbxw7 in neurodegeneration, to identify novel therapeutic targets.
Professor Jae-Heung Ko's research lab focuses on the molecular and genetic regulation of secondary cell wall biosynthesis and xylem development in vascular plants, particularly in Arabidopsis and poplar. The lab investigates key transcription factors such as MYB46, ANAC012, and PtaHB1, along with their regulatory networks, to understand how these factors control the formation of wood and vascular tissues. Using integrative approaches including transcriptomics, gene expression analysis, and functional genomics, the lab aims to decipher the signaling and transcriptional programs underlying secondary growth and stress responses in plants. Their work also explores the role of plant hormones and mechanical signals in cambium differentiation and xylem development.
Professor Sang Soo Han's research lab specializes in computational materials science, focusing on the design and simulation of advanced porous materials for energy applications. The lab employs advanced theoretical and simulation methods—such as grand canonical Monte Carlo, density functional theory (DFT), molecular dynamics, and reactive force fields (ReaxFF)—to investigate hydrogen storage, water stability, and thermal expansion behavior in metal-organic frameworks (MOFs) and covalent organic frameworks (COFs). Key research directions include optimizing material structures for high gravimetric and volumetric hydrogen uptake, enhancing stability under environmental conditions, and engineering novel frameworks with unique properties like negative thermal expansion. The lab bridges computational prediction with practical targets, such as meeting U.S. Department of Energy hydrogen storage goals.
Professor Ju-Young Moon's research lab focuses on the molecular mechanisms underlying renal inflammation and fibrosis in metabolic and diabetic kidney diseases. The lab investigates the roles of innate immune sensors such as the NLRP3 inflammasome and NLRP3-independent pathways in tubular and immune cells, with an emphasis on how metabolic stressors like hyperuricemia and angiotensin II drive kidney injury through oxidative stress and inflammatory signaling. Key research directions include the crosstalk between immune and renal epithelial cells, the contribution of T cell infiltration to interstitial damage, and the therapeutic potential of targeting NLRP3 and ROS pathways in acute and chronic kidney injury. The lab integrates in vitro models, primary cell cultures, and in vivo disease models to identify novel targets for intervention in diabetic nephropathy and other kidney diseases.
本研究室は、がんの発症・進行に関与するエピジェネティクスのメカニズムを解明することを主眼としています。特に、ヒストン修飾(メチル化・リン酸化)とDNA損傷修復の関連、およびがん細胞におけるエピジェネティックな制御機構の解明を進めています。また、人工知能を活用したがん画像診断の開発や、子宮体がん・卵巣がんなどの婦人科がんにおけるバイオマーカーの同定も重要な研究テーマです。
本研究室では、バイオ燃料電池の高効率化を目的として、直接電子移動(DET)型のバイオセンサーおよびバイオ電池の開発を進めています。主にフルクトースを燃料とする一次セル構造の開発や、酵素の表面配置制御による電極反応性能の向上を研究しています。特に、フルクトースデヒドロゲナーゼ(FDH)とラクカーゼ(LAC)を用いたセル設計や、酵素の三次元的配置制御技術の確立が特徴です。
Mahdi Khosravy教授の研究室は、サイバーセキュリティと画像認識の分野で、特にモデルインバージョン攻撃に対する耐性の向上をめざしたプライバシー保護技術の研究を推進しています。また、太陽光発電の効率的制御や、産業5.0に向けた人間とロボットの協働を実現する知能型システムの開発にも注力しており、AIを活用したスマートな制御技術や画像処理技術の実用化を目指しています。特に、人間の視覚特性を模倣した画像品質向上技術や、非定常な太陽光条件下でも最大出力を追跡する最適化アルゴリズムの開発が特徴です。
中川清隆教授の研究室は、植物由来の生理活性成分、特にポリフェノールやフラワノイド、グルコシダーゼ阻害剤などの代謝・吸収機構を解明することを主眼としています。特に、緑茶に含まれるエピガロカテキンガレート(EGCg)やアスタキサントシン、ルテオリン、1-デオキシノジリミシンなどの成分の体内動態とその抗酸化・抗糖尿病作用を、動物モデルおよび臨床試験を用いて解析しています。HPLCを用いた高感度分析法の開発も併行し、成分の正確な測定とその生理的意義の解明を目指しています。
Kimura教授の研究室では、膜汚染のメカニズム解明とその制御に焦点を当てた水処理技術の高度化を研究しています。特に膜バイオリアクター(MBR)における膜汚染の原因物質や操作条件(F/M比、泥齢など)の影響を実規模実験で解明しており、化学洗浄による再生可能性や、有機物の性質と膜の親和性の関係にも注力しています。持続可能な水処理プロセスの実現に向け、膜技術の信頼性と経済性を高める基盤技術の確立を目指しています。
Taguchi教授の研究室は、アルブミンやヘモグロビンを用いた新規医療材料の開発を柱としており、特にがん治療や炎症疾患の治療を目的としたドラッグデリバリー・システム(DDS)の構築に注力しています。血清アルブミンを核とするナノ粒子や、ヘモグロビンを基盤とする酸素キャリアの開発を通じて、薬物の長時間循環、高効率な標的送達、生体適合性の向上を実現しています。また、遺伝子治療用キャリアの開発や、一氧化炭素によるマクロファージのプロフェノタイプ制御といった、疾患メカニズムに直接働きかける革新的な戦略も展開しています。
Professor Kyoungphile Nam's research lab specializes in environmental microbiology and biogeochemistry, focusing on the fate, bioavailability, and bioremediation of environmental pollutants such as polycyclic aromatic hydrocarbons (PAHs) and heavy metals. The lab investigates microbial degradation mechanisms, sorption-desorption dynamics of contaminants in soils and engineered materials, and the role of soil properties—particularly organic matter and cation exchange capacity—in controlling contaminant mobility and ecological risk. Additionally, the lab explores biomineralization processes for sustainable applications, including self-healing concrete and metal toxicity prediction using biotic ligand models.
Professor Young Min Cho's research lab focuses on metabolic diseases, particularly type 2 diabetes and its complications, with a strong emphasis on molecular mechanisms underlying insulin resistance, mitochondrial dysfunction, and metabolic regulation. The lab investigates therapeutic targets such as GLP-1 signaling, SGLT2 inhibition, and mitochondrial transfer in stem cell therapy, aiming to translate basic findings into clinical applications. Recent work also explores the genetic architecture of complex traits, including carcass weight in Hanwoo cattle, reflecting a translational approach spanning human metabolism and agricultural genetics. The lab integrates molecular biology, genomics, and translational medicine to advance precision strategies for metabolic and kidney diseases.
Professor Kwang Seob Jeong's research lab specializes in colloidal quantum dots and nanocrystal-based optoelectronic materials, with a focus on manipulating electronic and optical properties through quantum confinement, ligand engineering, and defect passivation. The lab explores steady-state intraband transitions in mid-infrared regions, particularly in non-toxic and mercury-free systems like Ag₂Se and CdChalcogenide quantum dots, enabling applications in infrared photodetectors and solar cells. A key direction involves tuning carrier density and electronic transitions—from intraband to localized surface plasmon resonances—under ambient conditions, advancing practical optoelectronic devices with enhanced stability and performance.
Professor Byung-Ok Choi's research lab specializes in the genetic and molecular dissection of inherited neuromuscular disorders, with a primary focus on Charcot-Marie-Tooth (CMT) disease and distal myopathies. The lab employs advanced genomic technologies such as whole-exome sequencing and linkage analysis to identify novel disease-causing mutations and expand the genetic landscape of these conditions. Their work emphasizes genotype-phenotype correlations and the functional characterization of pathogenic variants in genes like PMP2, DGAT2, MYH14, and ADSSL1, contributing to precision diagnostics and potential therapeutic strategies. The lab also investigates the pathophysiological mechanisms underlying peripheral neuropathies and myopathies, particularly those with complex or overlapping clinical features.
Professor Jae-Joong Lee's research lab specializes in neuroscience and neuroimaging, focusing on the neural mechanisms underlying pain and emotion. The lab investigates how the brain constructs affective experiences—particularly pain and pleasure—through dynamic functional brain networks and personalized brain decoding. Using advanced fMRI techniques and computational modeling, the lab explores the representation of affective valence and intensity in key brain regions such as the prefrontal cortex, insula, and cingulate cortex. A central theme is the development of individualized brain decoding methods for chronic pain, aiming to improve diagnosis and treatment through neuroscientific insights.
中庵文夫教授の研究室では、リチウムイオン電池や固体電池の高効率化を目的として、酸化物イオンやリチウムイオンの高速拡散機構を第一原理計算を用いて解明しています。特に、ドーピング効果が酸化物セラミックスにおける点欠陥形成やイオン移動メカニズムに与える影響を理論的に分析しており、燃料電池やセンサー応用にも応用可能な材料設計の基盤を構築しています。また、固体電解質界面の安定性や電極反応機構の解明にも注力し、次世代エネルギー変換・貯蔵デバイスの実現に貢献しています。
当研究室は、主に筋肉の筋線維型の構造的・機能的特徴と、鉄コンクリート複合構造の接合部の力学的挙動に注目した研究を進めています。特に、家畜の筋肉におけるミオフィラーマイオシンアーゼのpH感受性を組織化学的に解明することで、筋線維型の多様性と機能的分担を明らかにしてきました。一方で、地震時の反復荷重に耐える鋼コンクリート複合部材の性能評価を目的に、パフォーブンド接続部の耐久性や応力伝達挙動を実験的に解明しています。
Yuki Hattori教授の研究室では、神経発達におけるミクログリアの役割とその動態に注目し、脳内での分布変化、神経幹細胞への影響、および発生段階に応じた機能的シグナル伝達のメカニズムを解明しています。特に、CXCL12シグナルによるミクログリアの移動制御や、神経細胞のサブタイプ分化への影響が焦点です。また、マクロファージ由来のミクログリア前駆細胞の脳内定着や、細胞外マトリックスの影響についても、画像解析と遺伝子操作を組み合わせたアプローチで研究を進めています。