世界の主要大学の研究室を探索 — 研究分野と主要論文を一目で確認できます。
ヤナヒラロ教授の研究室は、特発性肺線維症や間質性肺炎をはじめとする進行性肺線維化疾患の病態メカニズムを解明することを目的としています。特に肺上皮細胞のサルコーシスやプロファイブロティックなシグナル伝達経路、免疫細胞の異常活性化に注目し、個別化医療に応用可能な標的治療戦略の確立を目指しています。高スループットな薬剤スクリーニングや生体外モデル（精密切断肺スライス）を用いた新薬開発の基盤構築も重要な研究分野です。
Professor Ju-Hoon Lee's research lab specializes in microbial genomics and biotechnology, with a focus on bifidobacteria and bacteriophages. The lab investigates the genetic and molecular mechanisms underlying probiotic functions of bifidobacteria, including their adaptation to the gut environment and host-microbe interactions. A key research direction involves the development of bacteriophages as novel biocontrol agents and natural food preservatives to combat foodborne pathogens such as *E. coli*, *Salmonella*, and *Listeria*. The lab also explores plasmid biology and phage-host interactions to advance applications in food safety and probiotic therapeutics.
Professor Eun-Jung Yang's research lab specializes in advancing the safety and efficacy of soft tissue filler injections and facial rejuvenation procedures. Her work focuses on vascular anatomy mapping using Doppler ultrasound to prevent life-threatening complications such as skin necrosis and blindness during cosmetic interventions. The lab emphasizes real-time vascular visualization and safe injection techniques—particularly using cannulas in the preperiosteal layer and around high-risk areas like the nose and glabella. Her research also extends to thread lifting, where vascular structures are identified to minimize procedural risks.
Professor SeongMin Kim's research lab specializes in advanced energy conversion and functional materials, focusing on triboelectric nanogenerators (TENGs) for biomedical and environmental applications. The lab develops bioadhesive and highly tribopositive materials to enhance energy harvesting and tissue repair, while also exploring ferroelectric and piezoelectric effects in hybrid heterostructures for next-generation optoelectronic and photovoltaic devices. Innovative approaches in first-principles calculations and dielectric engineering are employed to optimize material performance at the nanoscale.
Professor Sun-Mi Lee's research lab specializes in metabolic engineering and synthetic biology, focusing on enhancing microbial platforms for sustainable biofuel and biochemical production. The lab develops advanced strain engineering strategies—particularly involving xylose utilization pathways and stress tolerance mechanisms—to improve the efficiency of yeast and bacterial systems in converting lignocellulosic biomass into ethanol, lipids, and solvents like butanol. Key research directions include optimizing metabolic pathways (e.g., xylose isomerase), overcoming inhibitor challenges in biomass hydrolysates, and engineering transporters for improved cellular fitness and productivity. The lab's work bridges synthetic biology, systems microbiology, and industrial biotechnology to advance renewable energy and bioproduct solutions.
Professor Ho Gyu Yoon's research lab specializes in the design and development of advanced functional materials, with a focus on conductive polymer composites, dielectric phantoms for electromagnetic simulation, epoxy resin curing kinetics, and dynamic polymer networks. The lab investigates the structure-property relationships of nanomaterials such as carbon nanotubes, graphene, and metal nanoparticles to enhance electrical, thermal, and electromagnetic shielding performance. A key research direction involves creating stimuli-responsive and self-healing materials through dynamic covalent chemistry, particularly using polysulfide-based networks. The lab also develops predictive kinetic models for polymer curing systems to optimize processing and performance in high-performance applications.
Professor Jin-Woo Bae's research lab focuses on the host-microbiota interactions in human health and disease, with a particular emphasis on the gut microbiome's role in metabolic disorders such as type 2 diabetes and neurodegenerative conditions like Alzheimer’s disease. The lab employs high-throughput sequencing technologies, including 454 pyrosequencing and viral metagenomics, to explore microbial community composition, diversity, and functional dynamics in human fecal and environmental samples. A key research direction involves deciphering how microbial modulation—especially through beneficial taxa like *Akkermansia*—can influence host physiology and offer novel therapeutic strategies. The lab also investigates the impact of medical interventions, such as radiotherapy, on gut microbial homeostasis and associated complications.
ノザキ教授の研究室は、寄生性原虫、特にアメーバの病原体であるイントラマトゥス・エントロコアの細胞内小器官と代謝機構に焦点を当てた研究を行っています。特に、酸素を必要としない環境下でも機能するミトコンドリア由来小器官（MROs）の構造・機能の解明や、Fe-Sクラスター形成機構、システイン合成経路、および食細胞の成熟メカニズムの分子機構を解析しています。これらの研究は、病原性のメカニズム解明と、寄生虫特異的標的の同定に貢献しています。
Koichiro Yasaka教授の研究室では、画像診断における深層学習（CNN）の応用に注力しており、動脈期・遅延期強化CTを用いた肝腫瘍の分類や、Gd-EOB-DTPA強化MRIを用いた肝線維化のステージングに向けたAI支援診断技術の開発を進めています。画像ノイズ低減技術やテクスチャ解析を応用したレーマンスティクス解析の最適化も行い、臨床的応用に向けた高精度で信頼性の高い画像診断支援システムの構築を目指しています。
Fan-Yan Wei教授の研究室は、RNA修飾と翻訳調節の分子機構に焦点を当てた基礎研究を推進しています。特にtRNAの化学修飾（ms²t⁶Aや2'-Oメチル化）がタンパク質合成の正確性に与える影響を解明しており、その異常と代謝疾患・神経疾患の関連を明らかにしています。また、m⁶A修飾やCdk5の制御機構を通じて、細胞周期や神経可塑性の調節にも寄与していることが示されています。
Yoshikawa教授の研究室は、がん治療の新しいアプローチとして、常温大気圧プラズマを用いた治療法の開発を主眼としています。特に、プラズマ活性化培地（PAM）が卵巣がんや子宮体がんの転移や増殖を抑制するメカニズムの解明を進めています。また、TP53変異を有するがんに対して効果を示す薬剤（PRIMA-1MET）の臨床的応用可能性についても研究を展開しており、がんの再発予防や栄養状態のバイオマーカーとしてのPNIの意義解明も行っています。
Masato Nagino教授の研究室は、胆道癌をはじめとする肝・胆道・膵疾患の治療における手術的アプローチの最適化を目的としています。特に高位胆管癌における積極的切除戦略や、門脈・肝動脈の同時再建を伴う大規模肝切除の技術的・予後的検討が中心です。また、術後の腸管バリア機能の回復や胆汁代替療法の有効性についても臨床的・実験的根拠を積み重ねています。
Toshiro Matsui教授の研究室は、食事誘因の血糖上昇を抑える働きを示す天然由来化合物のスクリーニングとそのメカニズム解明を柱としています。特にアントシアニンやカテキン、テアフラビン、プロポリスに含まれるフェノール化合物のαグルコシダーゼ阻害作用に注目し、小腸に存在する膜貫通型酵素を模倣した阻害実験を実施しています。その結果、マルターゼに対して特異的な阻害作用を示す化合物の同定や、構造と活性の相関関係の解明が進んでいます。
Terakawa教授の研究室では、レーザーを用いた新規材料加工技術を開発し、生体適合性・生分解性を備えた次世代エレクトロニクスの実現を目指しています。特に、フェムト秒レーザーを用いた生分解性ポリマーのナノ構造制御や、セルロースナノファイバーからの高導電性カーボンの作製、さらには生分解性のTriboelectricナノジェネレータの開発が主な研究テーマです。環境に配慮したスマートデバイスの創出を目的としています。
Professor Sejin Kwon's research lab specializes in advanced materials and systems for sustainable energy conversion and storage, with a primary focus on hydrogen generation and fuel cell technologies. The lab develops compact, efficient, and safe hydrogen production systems using chemical hydrides like sodium borohydride and methanol, employing tailored heterogeneous catalysts to enable controlled and continuous hydrogen release. Key research directions include catalytic methanolysis and steam reforming of methanol, as well as the integration of hydrogen generation units with proton exchange membrane fuel cells (PEMFCs) for portable and distributed energy applications. The lab also explores innovative thermal management strategies, such as using hydrogen peroxide decomposition for in-situ heat supply in micro-reformers.
Professor Jong-Gwan Yook's research lab specializes in microwave and millimeter-wave engineering with a focus on non-invasive sensing, advanced antenna design, and electromagnetic compatibility. The lab develops innovative radar-based vital sign monitoring systems, fluidic sensors for biomedical applications, and compact, high-frequency packaging solutions for integrated circuits. Research also extends to anti-drone technologies using intentional electromagnetic interference and bio-inspired pressure sensing systems for wearable and smart sensing applications.
Professor Yong Min Lee's research lab specializes in advanced energy storage systems, with a primary focus on solid-state batteries and lithium-metal batteries. The lab investigates critical interfacial phenomena, such as solid electrolyte interphase (SEI) formation and stabilization, to enhance electrochemical performance and longevity. Key research directions include the development of novel electrolyte additives, innovative electrode architectures with optimized component distribution, and the integration of digital twin technologies for real-time monitoring and prediction of battery behavior. The lab also explores conductive additive synergies and scalable fabrication methods to enable high-energy-density, safe, and durable all-solid-state batteries.
Professor Seul Ki Han's research lab specializes in advanced signal processing, intelligent monitoring systems, and biomedical engineering applications. The lab focuses on developing data-driven methodologies for real-time condition monitoring and predictive maintenance in precision manufacturing, as well as enhancing navigation accuracy through advanced filtering techniques like Kalman filtering. Additionally, the lab explores rehabilitation technologies and human physiological responses to environmental stimuli, particularly in stroke recovery and therapeutic environments. These interdisciplinary efforts integrate sensor fusion, signal analysis, and control systems to improve health outcomes and industrial efficiency.
Professor Myung-Shik Lee's research lab focuses on molecular mechanisms underlying metabolic regulation, insulin resistance, and cellular stress responses, with a particular emphasis on fibroblast growth factor 21 (FGF21), mitochondrial dysfunction, and the interplay between inflammatory cytokines and apoptosis. The lab investigates how metabolic stressors such as free fatty acids and mitochondrial DNA depletion affect cellular signaling pathways, including JNK/IRS-1 and NF-κB, and explores their roles in insulin resistance and metabolic diseases. Additionally, the lab examines the role of growth factors like TGF-β1 in fibrotic processes and the regulation of extracellular matrix remodeling in disease models. Their work integrates molecular biology, cell signaling, and translational metabolism to identify therapeutic targets for diabetes, liver disease, and cancer.
Professor Jiashun Mao's research lab specializes in the integration of machine learning, molecular simulation, and chemical informatics to advance computational drug discovery and materials science. The lab focuses on developing data-driven models that bridge molecular representation (such as IUPAC nomenclature and SMILES) with deep generative models, particularly diffusion models, for intelligent molecular design. A key research direction involves leveraging natural language processing techniques for chemical language to enable interpretable and editable molecular generation, while also improving the accuracy of property prediction—such as dielectric constants—for functional materials. The lab emphasizes the synergy between wet-lab experiments, molecular dynamics simulations, and AI-driven modeling to ensure physical realism and practical applicability.
