ソウル大学、KAIST、延世大学など韓国QSトップ10大学の研究室情報です。
Professor Dae Sung Yoon's research lab specializes in the development of advanced micro- and nanoscale devices for biomedical diagnostics and regenerative medicine. The lab focuses on innovative point-of-care diagnostics using isothermal amplification techniques like RT-LAMP combined with lateral flow assays, as well as the design of functionalized biomaterials for controlled drug delivery. Key research directions include microfluidic chip fabrication for rapid thermal cycling, impedance sensing in lab-on-a-chip systems, and the integration of 2D materials like graphene with biocompatible platforms for wearable biosensors. The lab also explores the electrical characterization of nanomaterials using techniques such as Kelvin probe force microscopy to understand surface potential and work function at the nanoscale.
Professor Jin Hee Lee's research lab focuses on molecular oncology and metabolic disease mechanisms, with a strong emphasis on tumor suppressor genes such as PRKCDBP in colorectal cancer and the role of insulin resistance in vascular dysfunction associated with Type 2 diabetes. The lab investigates epigenetic regulation, including promoter hypermethylation, and signaling pathways like NF-κB and Akt in cancer and metabolic disorders. Additionally, the lab explores bioactive natural products, particularly phosphonate compounds, and their potential as enzyme inhibitors or therapeutic agents. The integration of molecular pathology, translational research, and clinical implications defines the lab’s interdisciplinary approach.
Professor Jooyoung Kim's research lab focuses on cellular signaling mechanisms, particularly the regulation of ion channels such as TRPC and CFTR, and their roles in neuronal and glial cell function. The lab investigates protein-protein interactions, scaffolding proteins (e.g., Homer, Shank2), and intracellular signaling pathways involving calcium, reactive oxygen species, and kinases in neurodegenerative and developmental disorders. A key focus is on understanding how dysregulation of these pathways contributes to diseases such as Parkinson’s disease, endometriosis, and demyelinating conditions.
Professor Soo-Jeong Cho's research lab specializes in gastrointestinal oncology and molecular gastroenterology, with a focus on the pathogenesis, risk stratification, and therapeutic strategies for gastric and colorectal cancers. The lab investigates molecular mechanisms underlying carcinogenesis, particularly the roles of epigenetic regulators like KMT2C and signaling pathways such as NF-κB in gastric and colon cancer progression. It also explores the impact of medical therapies—such as statins and antiplatelets—on cancer risk and treatment outcomes, integrating translational research with clinical endoscopy and pathology. The lab emphasizes precision medicine through biomarker discovery and validation of staging systems like OLGA and OLGIM for early gastric cancer risk prediction.
Professor Suk-Won Kim's research lab focuses on translational oncology, with a primary emphasis on breast cancer and anaplastic thyroid carcinoma. The lab investigates molecular mechanisms underlying cancer progression, including inflammation-driven metastasis, EGFR signaling, and tumor microenvironment interactions. Key research directions include identifying therapeutic targets such as IL-1β and MMPs, evaluating diagnostic and staging strategies (e.g., bone scans and hypercalcitoninemia), and developing innovative techniques for non-palpable breast lesion localization using ICG-HA. The lab integrates molecular biology, clinical oncology, and diagnostic imaging to improve patient outcomes through precision medicine approaches.
Professor Woo In Lee's research lab specializes in pharmacogenomics and membrane transport biology, focusing on the molecular mechanisms and clinical implications of solute carrier (SLC) transporters—particularly OATP and OAT family members—in drug disposition, tissue penetration, and cancer biology. The lab investigates how genetic variations in transporter genes (e.g., *SLCO1A2*, *SLCO1B3*) influence interindividual variability in drug response, toxicity, and efficacy, with translational applications in personalized medicine. A key research direction involves the aberrant expression of drug transporters in cancer, such as OATP1B3 overexpression in colorectal adenocarcinoma, and its functional impact on chemotherapy response. The lab also explores the role of transporters in organ-specific drug delivery and renal handling of xenobiotics.
Professor Do-kyung Kim's research lab specializes in the design and development of advanced fluorescent probes for biomedical imaging, with a strong focus on two-photon excitation technologies. The lab pioneers novel fluorophores and sensing systems that enable high-contrast, background-free imaging in live tissues and organisms, particularly for monitoring biologically relevant analytes such as fluoride, hydrazine, and enzyme activities like monoamine oxidases (MAOs). Their work integrates molecular design, photophysics, and in vivo imaging to address critical challenges in disease diagnostics, including Alzheimer’s disease pathology. The lab emphasizes the creation of responsive, selective, and ratiometric probes for real-time, non-invasive biological monitoring in complex environments.
Professor U Kang's research lab specializes in large-scale data analytics, with a focus on scalable graph and tensor mining for billion-node graphs and massive multi-dimensional data. The lab develops high-performance, distributed algorithms and systems—such as PEGASUS and HADI—designed to efficiently compute graph properties like diameter, radius, and centrality on Hadoop/MapReduce platforms. A key research direction involves rethinking traditional graph abstractions, proposing novel models like the hub-and-spoke structure and the Slash Burn method to improve layout, compression, and analysis of real-world networks. The lab also explores efficient tensor decomposition techniques for knowledge graphs, social networks, and streaming data, emphasizing scalability and real-world applicability.
Professor Kyoungmi Kim's research lab focuses on cellular communication mechanisms, particularly through extracellular vesicles (EVs) and mitochondrial noncoding RNA, with a strong emphasis on their roles in aging, neurodegenerative diseases like Alzheimer’s, and cellular senescence. The lab investigates the molecular mechanisms of mRNA surveillance and translation regulation, especially involving CBP80/20 and Nonsense-Mediated Decay (NMD), as well as the identification of senescence-specific surface markers like DPP4 for targeted clearance. A central theme is the discovery of novel biomarkers and therapeutic targets in liquid biopsies using EVs and mitochondrial RNA dynamics.
Professor Jeong Eun Lee's research lab focuses on neuroinflammatory mechanisms in neurodegenerative diseases, particularly the dynamic role of microglia in retinal tissue homeostasis and injury response. The lab also investigates the neuroanatomical underpinnings of cognitive impairment in Parkinson’s disease and the impact of systemic conditions such as end-stage renal disease on cancer incidence and patient outcomes. Additionally, the lab explores psychosocial and organizational factors affecting mental health and professional well-being in vulnerable populations, including adolescents and social service workers.
Professor Jaeseung Jeong's research lab specializes in nonlinear dynamics and complex systems analysis applied to neurological and physiological data. The lab focuses on understanding brain network organization, particularly in neurodegenerative diseases such as Alzheimer’s and Parkinson’s, using advanced signal processing techniques like wavelet analysis, correlation dimension estimation, and community detection in neural connectomes. A key research direction involves distinguishing neurological disorders through subtle changes in EEG dynamics, emphasizing the detection of determinism and complexity in short, noisy time series. The lab also investigates the functional role of spontaneous behaviors like eyeblinking in cognitive processing, linking them to underlying brain dynamics.
Professor Yong-Jae Moon's research lab specializes in solar physics, with a primary focus on the magnetic dynamics of the Sun, particularly the generation, transport, and evolution of magnetic helicity in active regions. The lab investigates the physical mechanisms behind solar flares, coronal mass ejections (CMEs), and sympathetic flare events using high-cadence magnetograms and multi-wavelength observations from SOHO and SDO. A key research direction involves applying machine learning techniques, such as Convolutional Neural Networks (CNNs), to predict solar flare occurrences based on magnetic field data. The lab also explores the force-free nature of solar magnetic fields and the role of photospheric motions in driving eruptive space weather phenomena.
Professor Jong-Sung Lee's research lab specializes in dermatological and cosmetic biotechnology, focusing on the molecular mechanisms of natural compounds in skin health, aging, and inflammation. The lab investigates bioactive phytochemicals—such as ginsenosides, magnolol, honokiol, asiaticoside, rosmarinic acid, and flavonoids—through in vitro and ex vivo models to elucidate their anti-aging, antioxidant, anti-inflammatory, and immunomodulatory effects. Key research directions include collagen synthesis regulation, UV protection, and skin barrier function enhancement using natural and probiotic-derived compounds.
Professor Jeong Ho Lee's research lab focuses on understanding the genetic and molecular mechanisms underlying brain development, neurological disorders, and somatic mosaicism. The lab specializes in identifying somatic mutations in the brain—particularly in genes like MTOR, PI3K-AKT, and ciliary pathway genes—that contribute to epilepsy, Alzheimer’s disease, and ciliopathies. Using advanced genomics, computational methods (such as RePlow for low-VAF mutation detection), and innovative neural interface technologies (e.g., Au nanonetwork-based ECoG systems), the lab bridges genomics, neuroscience, and biomedical engineering to uncover disease mechanisms and develop precision diagnostics. A central theme is the role of somatic mosaicism and cellular signaling pathways in neurodevelopmental and neurodegenerative diseases.
Professor Ji Hoon Kang's research lab specializes in biomedical and materials science, with a strong focus on translational cardiovascular research and advanced functional materials. The lab investigates optimal antiplatelet therapy strategies in percutaneous coronary intervention (PCI), particularly examining racial differences in treatment outcomes and long-term antithrombotic management in East Asian populations. In parallel, the lab explores solution-processed organic semiconductor materials, such as TIPS-pentacene/PαMS blends, for next-generation organic thin-film transistors, combining advanced structural and electrical characterization techniques. These dual research directions reflect a commitment to both clinical cardiology innovation and materials engineering for next-generation medical devices.
Professor M. James Jee's research lab specializes in observational cosmology and strong/weak gravitational lensing using high-resolution Hubble Space Telescope data, with a focus on mapping dark matter distributions in galaxy clusters. The lab develops advanced image analysis techniques—particularly point spread function (PSF) modeling and principal component analysis—to correct for instrumental and optical distortions in ACS/WFC data, enabling precise weak-lensing measurements. Key research directions include studying the mass structure of high-redshift clusters, probing the nature of dark matter through anomalies like 'dark cores,' and constructing accurate PSF libraries for improved photometric and morphological analysis. The lab also contributes to digital scholarly infrastructure, such as virtual libraries for Latin American studies, reflecting a broader commitment to open science and data accessibility.
Professor Jin Chul Paeng's research lab specializes in molecular imaging and nuclear medicine, focusing on the clinical application of PET and SPECT tracers for accurate diagnosis, treatment planning, and prognosis prediction in oncology and neurological disorders. The lab investigates tumor heterogeneity using radiomic features from FDG-PET/CT to predict treatment response in lung cancer, evaluates advanced internal radiation therapy dosimetry using ⁹⁰Y-microsphere PET/CT, and explores novel tracers like ¹¹C-methionine for improved epilepsy surgery evaluation. The lab also advances multimodal imaging techniques to enhance diagnostic accuracy in musculoskeletal and oncologic conditions.
Professor Jinhee Lee's research lab focuses on translational cancer biology and metabolic disease mechanisms, with a strong emphasis on tumor suppressor genes like PRKCDBP in colorectal carcinogenesis and the molecular pathways underlying insulin resistance in type 2 diabetes. The lab investigates epigenetic regulation, such as promoter hypermethylation, in cancer progression and explores the pathophysiology of vascular dysfunction in diabetic models. Additionally, the lab contributes to clinical research on early detection of pancreatic cancer in high-risk diabetic populations and evaluates anesthetic strategies in pediatric sedation.
Professor Soo-Yeon Cho's research lab specializes in the development of advanced two-dimensional (2D) materials and nanostructured heterostructures for next-generation electronic and sensing applications. The lab focuses on enhancing gas sensing performance through controlled doping, surface functionalization, and nanoarchitecture engineering—particularly using MoS₂, black phosphorus, and p-type metal oxide semiconductors. Key research directions include improving sensitivity, selectivity, and response kinetics in volatile organic compound (VOC) and toxic gas sensors, with an emphasis on scalable, wearable, and flexible sensing platforms. The lab also explores fundamental charge transfer mechanisms at 2D material interfaces to enable high-performance, low-power devices for real-world applications.
Professor Woong Kim's research lab specializes in advanced energy storage systems, with a focus on nanomaterial-based supercapacitors and bio-integrated nanodevices. The lab explores high-performance, flexible, and solid-state supercapacitors using carbon nanotubes, ionic liquids, and water-in-salt electrolytes to achieve exceptional energy and power densities. A key research direction involves the integration of nanomaterials with biological systems, demonstrated by the successful direct interfacing of silicon nanowires with living cells for long-term cell culture and gene delivery. The lab also investigates ion transport dynamics in concentrated electrolytes and novel electrode architectures to enable ultrafast, stable, and scalable energy storage solutions.
